The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V2210 | SR33805 | 121345-64-0 | SR33805 is a novel and potent antagonist of Ca2+ channel with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively, and it blocks L-type but not T-type Ca2+ channels. |
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V3759 | Suvecaltamide (MK-8998) | 953778-58-0 | Suvecaltamide (MK8998; compound 33;MK-8998) is a novel potent and selective antagonist of the T-type calcium channel that is being investigated as a potential new therapeutic for the treatment of schizophrenia. |
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V0610 | Clevidipine Butyrate | 167221-71-8 | Clevidipine (Cleviprex) is a potent and short acting, dihydropyridine-based L-type calcium channel blocker used forreducingblood pressure when oral therapy is not feasible or not desirable. |
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V1702 | Fluticasone propionate | 80474-14-2 | Fluticasone Propionate (formerly CCI187881; CCI 187881;Cutivate, Flixonase, Flixotide, Flonase, Flovent) is a potent and synthetic glucocorticoid medication approved as a nasal spray for use in thetreatment ofnon-allergic and allergic rhinitis. |
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V1714 | Clobetasol propionate | 25122-46-7 | Clobetasol propionate (formerly CGP-9555, CCl-4725; CGP9555; CCl4725;Clobex Cosvate; Temovate; Olux Tenovate) is a topical corticosteroid used as an anti-inflammatoryfor treatment of various skin disorders including eczema and psoriasis. |
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V1705 | Betamethasone Dipropionate | 5593-20-4 | Betamethasone Dipropionate (Alphatrex; BetaVal; Diprolene;SCH-11460; SCH11460;Diprolene AF; Diprosone; Luxiq; Betamethasone 17,21-dipropionate) is a synthetic glucocorticoid steroid with anti-inflammatory and immunosuppressive activities. |
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V1429 | Isradipine (PN 200-110) | 75695-93-1 | Isradipine (formerly known as PN-200-110, PN-205-033, PN-205-034; DynaCirc, Prescal, Lomir)is a potent and selective L-type voltage-gated CBB/calcium channel blocker of the dihydropyridine class with antihypertensive effects. |
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V1689 | Ivacaftor (VX-770) | 873054-44-5 | Ivacaftor (formerly also known as VX-770; trade name:KALYDECO andSymdeko) is a potent and orally bioactive potentiator of CFTR (cystic fibrosis transmembrane conductance regulator) with potential anti-fibrotic activity. |
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V1700 | Loteprednol etabonate | 82034-46-6 | Loteprednol etabonate (Lotemax; Alrex; HGP-1; Loterox; Locort;P-5604; HGP1; Lenoxin, CDDD-5604), the esther form of Loteprednol, is a potent glucocorticoid receptor agonist approved as a medication used in treatment of inflammation of the eye due to allergies. |
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V1711 | Betamethasone Valerate (BV; BET) | 2152-44-5 | Betamethasone Valerate (BV; BET; Betoid; Valison; 9α-Fluo; Valisone; Bedermin; Betneval; Beta-Val; Bextasol; Dermosol; Stanoval) is a moderately potent andcommonly used glucocorticoid steroid with anti-inflammatory and immunosuppressive activities. |
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V13298 | Protopine | 130-86-9 | Protopine (Corydinine) is an isoquinoline alkaloid and a specific, reversible and competitive inhibitor of acetylcholinesterase. |
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V1713 | Cortisone acetate | 50-04-4 | Cortisone acetate (NSC49420;NSC-49420;Cortone acetate; Cortisyl; Incortin), a steroid hormone,is an acetate ester prodrug form of cortisone withglucocoriticoid and mineral corticoid activities. |
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V19955 | Diltiazem free base | 42399-41-7 | Diltiazem ((Tiazac; CRD-401;Dilticard;RG83606) is a nondihydropyridines (non-DHP) calcium channel blockerwith vasodilating activity. |
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V1706 | Desonide (Budesonide acetonide) | 638-94-8 | Desonide(Budesonide acetonide),a non-fluorinated corticosteroid approved as anti-inflammatory drug, is a low potency topically used corticosteroid with anti-inflammatory activities. |
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V1709 | Deflazacort (MDL 458) | 14484-47-0 | Deflazacort (ML-458; ML458;DL-458-IT, L-5458;Cortax; Decortil; Deflanil; Flezacor;trade name:Emflaza)is a potent glucocorticoid drug approved for use as an anti-inflammatory and immunosuppressant. |
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V0920 | Nisoldipine | 63675-72-9 | Nisoldipine (BAY-K-5552;Bay K-5552, Sular, Baymycard, Nisocor, Syscor) is a novel CCB-calcium channel blocker of the dihydropyridine (DHP)class with vasodilating and antihypertensive effects. |
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V1704 | Budesonide | 51333-22-3 | Budesonide (Rhinocort;Budicort; Entocort;Rhinosol; Pulmicort; Symbicort; Noex Entocort EC) is a synthetic glucocorticoid steroid approved for use in the treatment ofinflammatory conditions such as asthma, non-infectious rhinitis, and nasal polyposis. |
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V1885 | Isoxazole 9 (ISX-9) | 832115-62-5 | Isoxazole 9 (also known as Isx-9) is a synthetic promotor/inducer of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs). |
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V1199 | Lacidipine (GX-1048, GR-43659X, SN-305, Lacipil, Motens) | 103890-78-4 | Lacidipine (GX-1048, GR-43659X, SN-305; GX1048, GR43659X, SN305; Caldine, Lacimen, Lacipil, Midotens, Motens)is a potent and 3rd-generation L-type CCB (calcium channel blocker) that has been approved in 1990s for treating high blood pressure. |
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V1710 | Triamcinolone Acetonide | 76-25-5 | Triamcinolone acetonide (Acetospan; Adcortyl A; AllerNaze;Kenalone; Nasacort; Aristocort; Aristoderm. |
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