|
V2735
|
CCT245737 S-isomer
|
1489389-23-2 |
CCT245737S-enantiomer, the S-isomer ofCCT-245737, is an orally available and selective ATP-competitive inhibitor of CHK1 (checkpoint kinase 1) with an IC50 of 30-220 nM. |
|
V2870
|
Cyantraniliprole
|
736994-63-1 |
Cyantraniliprole (also known as HGW-86), an anthranilic diamide analog, is a novel and potent second-generation insecticide which is able to deter insect feeding and reduce disease transmission. |
|
V2754
|
JTE 013
|
547756-93-4 |
JTE 013 (JTE-013) is a novel potent and selective S1P2 (sphingosine-1-phosphate 2) antagonist with IC50 of 17.6 nM. |
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V2719
|
Lanabecestat camsylate
|
1522418-41-2 |
Lanabecestat camsylate (formerly known as AZD-3293; LY3314814), the camsylate salt ofLanabecestat, is a BACE inhibitor that inhibits beta-secretase 1 cleaving enzyme (BACE) with aKiof 0.4 nM. |
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V2736
|
Ocifisertib (CFI-400945) fumarate
|
1616420-30-4 |
CFI400945 (CFI-400945) fumarate is a potent, selective, and orally bioavailable PLK4 (polo-like kinase 4) inhibitor withIC50 value of 2.8 ±1.4 nM and potential antineoplastic activity. |
|
V1641
|
Prucalopride HCl (R-108512, R-93877)
|
179474-80-7 |
Prucalopride HCl (formerly known asR93877;R-108512; Resolor; Resotran;trade name: Motegrity),the hydrochloride salt of prucalopride which is a novel enterokinetic compound and is the first representative of the benzofuran class, is a novel selective, high affinity 5-HT (serotonin) receptor agonist for 5-HT4A and 5-HT4B receptor with anti-constipation effects. |
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V2838
|
SNG-1153
|
1446712-19-1 |
SNG1153 is a synthetic ER-α36 modulator which shows promising activities in various in vitro and in vivo models. |
|
V2717
|
STO-609 acetate
|
1173022-21-3 |
STO-609 acetate is a novel, potent, specific and cell-permeable inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms with Ki values of 80 and 15 ng/ml, respectively, it also inhibits their autophosphorylation activities. |
|
V2670
|
Vacquinol-1 2HCl
|
2309312-85-2 |
Vacquinol-1 dihydrochloride (also known as NSC-13316; NSC13316)is an MKK4 (mitogen-activated proteinkinasekinase4) activator with antitumor activity. |
|
V2793
|
Verubecestat TFA
|
2095432-65-6 |
Verubecestat TFA (also known as MK-8931; SCH-900931), the trifluoroacetic acid salt form of MK-8931, is a beta-secretase 1 and BACE1 inhibitor with anti-AD (Alzheimer's disease) activity. |
|
V2795
|
Voxelotor (GBT-440; Oxbryta)
|
1446321-46-5 |
Voxelotor (formerly known as GBT-440; trade name: Oxbryta) is a potent and orally bioactive allosteric effector of sickle cell hemoglobin. |