Progesterone receptor (PR) is a member of the steroid/thyroid hormone-retinoid receptor superfamily of ligand-activated nuclear transcription factors.
The development, differentiation, and maintenance of female reproductive tissue depends heavily on progesterone receptor.The ability of the progesterone receptor to bind to a wide range of ligands results in a wide range of transcriptional responses, including full agonism, full antagonism, and several mixed profiles in between. Progesterone receptors, such as progesterone, cause the PR ligand binding domain (LBD) to change its conformation, which in turn controls subsequent gene regulatory cascades.
Human PR-A and PR-B are two different types of progesterone receptors that mediate the biological response to progesterone in humans.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V67772 | 17α-Hydroxyprogesterone-13C3 (17-Hydroxyprogesterone-13C3; 17-OHP-13C3) | 1356154-92-1 | 17α-Hydroxyprogesterone-13C3 is a 13C (carbon 13)-labeled 17α-Hydroxyprogesterone. |
|
V67766 | 17α-Hydroxyprogesterone-d8 (17-Hydroxyprogesterone-d8; 17-OHP-d8) | 850023-80-2 | 17α-Hydroxyprogesterone-d8 is the deuterium labelled form of 17α-Hydroxyprogesterone. |
|
V77901 | Altrenogest-d5 (Allyltrenbolone-d5; Allyltrenbolone-d5; RU2267-d5) | Altrenogest-d5 is the deuterium labelled form of Altrenogest. | |
|
V67604 | ARD-61 | 2316837-08-6 | ARD-61 is a highly efficient and specific PROTAC androgen receptor (AR) degrader. |
|
V19639 | Desogestrel | 54024-22-5 | Desogestrel (Org-2969, Desogen; Org2969, Desogestrelum, Org 2969, Cerazette) is a synthetic progestin derivative approved as an oral contraceptive medication used in birth control pills for women. |
|
V20258 | Drospirenone | 67392-87-4 | Drospirenone (MSp; SH-470; ZK-30595; LF-111; Slynd; Yasminelle; Yaz; Nextstellis) is a synthetic progestogen approved for used as an oral contraceptive alone or in combination with other medicaitons (Trade name: Alone: Slynd; With estradiol: Angeliq; With ethinylestradiol: Yasmin, Yasminelle, Yaz, others With estetrol: Nextstellis). |
|
V67773 | Drospirenone-d4 | 2376035-94-6 | Drospirenone-d4 is the deuterium labelled form of Drospirenone. |
|
V79659 | Dydrogesterone-d6 (dydrogesterone d6) | Dydrogesterone-d6 is the deuterated form of Dydrogesterone. | |
|
V65080 | Gestodene-d6 (SHB 331-d6; WL 70-d6) | 1542211-40-4 | Gestodene-d6 is the deuterated form of Gestodene. |
|
V67771 | Medroxyprogesterone-d3 (17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3) | 162462-69-3 | Medroxyprogesterone-d3 is the deuterium labelled form of Medroxyprogesterone. |
|
V67765 | Melengestrol acetate | 2919-66-6 | Melengestrol acetate is a progesterone analogue that works as an orally bioactive corticosteroid that promotes endometrial proliferation, maintenance of pregnancy, and delayed menstrual activity. |
|
V78844 | Melengestrol acetate-d2 | Melengestrol acetate-d2 is the deuterium labelled form of Melengestrol acetate. | |
|
V76777 | Melengestrol acetate-d3 | Melengestrol acetate-d3 is the deuterium labelled form of Melengestrol acetate. | |
|
V79088 | Melengestrol acetate-d6 | Melengestrol acetate-d6 is the deuterium labelled form of Melengestrol acetate. | |
|
V26605 | Norethindrone | 68-22-4 | Norethindrone (Norethisterone; sold under many trade names) is a synthetic progestin used as an orally active contraceptive for birth controls. |
|
V15494 | Norethindrone enanthate | 3836-23-5 | Norethindrone enanthate (LG-202; NSC-9564; SH-393;LG202; NSC9564; SH393; Norigest) is the 17-O-enanthate ester of Norethindrone (Norethisterone), which is a synthetic progestin, anantigonadotropic agent and an orally activehormonal contraceptive used for birth control. |
|
V26611 | Norgestimate | 35189-28-7 | Norgestimate is a synthetic progestin analog, an orally bioactive progestin with selective progestogenic activity and minimal androgenic effects. |
|
V64134 | Norgestimate-d6 (Norgestimate-d6) | 1263194-12-2 | Norgestimate-d6 is the deuterium labelled form of Norgestimate. |
|
V63506 | Norgestrel-d6 (levonorgestrel d6) | 2376035-98-0 | Norgestrel-d6 is the deuterated form of Levonorgestrel. |
|
V67770 | Org OD 02-0 (10-Ethenyl-19-norprogesterone) | 13258-85-0 | Org OD 02-0 (10-Ethenyl-19-norprogesterone) is a membrane progesterone receptor alpha (mPRα) specific agonist (IC50= 33.9 nM). |
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