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V30953
|
4-Octyl Itaconate
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3133-16-2 |
4-Octyl Itaconate is a novel, potent and cell-permeable analog of itaconate, which is an emerging determinant of inflammation in activated macrophages and an anti-inflammatory metabolite that can activate Nrf2 (an anti-inflammatory transcription factorvia alkylation of KEAP1. |
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V13644
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Dimethyl Fumarate
|
624-49-7 |
Dimethyl Fumarate(DMF, trade namesTecfidera;Skilarence),the methyl ester of fumaric acid, is a potent,orally bioactive and brain-penetrant immunomodulator and Nrf2activator. |
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V10659
|
Sulforaphane (BroccoPhane; Detoxophane)
|
4478-93-7 |
Sulforaphane (BroccoPhane; Detoxophane) is a naturally-occurring isothiocyanatewidely found in consumed vegetables. |
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v5066
|
Brusatol (NSC 172924)
|
14907-98-3 |
Brusatol (also known as NSC 172924; BRN 1444847), a naturally-occuring product isolated from theBrucea javanicaplant, is a novel, potent and unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells and A549 xenografts to cisplatin and other chemotherapeutic drugs. |