yingweiwo
  1. Home
  2. Products
  3. Signaling Pathways
  4. Neuronal Signaling
  5. ChE

ChE

ChE

The central nervous system contains a family of enzymes known as cholinesterase (ChE), which catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid. This reaction is required for cholinergic neurons to return to their resting state after activation. It is one of many crucial enzymes required for the healthy operation of human nervous systems.
There are two: butyrylcholinesterase (BChE, acylcholine acylhydrolase), also referred to as nonspecific cholinesterase or pseudocholinesterase, and acetylcholinesterase (AChE, acetylcholine hydrolase). While BChE is made in the liver and is mainly found in plasma, AChE is mainly found in the blood on the membranes of red blood cells, at neuromuscular junctions, and in neural synapses. The relative substrate preferences of the two types of cholinesterase are different: AChE hydrolyzes acetylcholine more quickly while BChE hydrolyzes butyrylcholine more quickly.

ChE related products

Structure Cat No. Product Name CAS No. Product Description
(+)-Balanophonin V71637 (+)-Balanophonin 215319-47-4 (+)-Balanophonin is a natural phenolic compound extracted from Passiflora edulis and has antioxidant, anticholinesterase, anti~inflammatory, anticancer and anti-neurodegenerative activities.
(R)-Donepezil ((R)-Donepezil; (R)-E2020 free base) V71626 (R)-Donepezil ((R)-Donepezil; (R)-E2020 free base) 142698-19-9 (R)-Donepezil is the R-enantiomer of Donepezil .
(rac)-Rivastigmine-d6 (rivastigmine d6) V71649 (rac)-Rivastigmine-d6 (rivastigmine d6) 194930-04-6 (rac)-Rivastigmine-d6 is the deuterated racemate of Rivastigmine.
(Rac)-Sclerone V71697 (Rac)-Sclerone 19638-58-5 (Rac)-Sclerone is a naturally occurring compound that can be extracted from the green shell of pecans.
(Rac)-TZ3O V101850 (Rac)-TZ3O 2218754-19-7 (Rac)-TZ3O is the (Rac) isomer of TZ3O.
(S)-Donepezil ((S)-E2020 free base) V71614 (S)-Donepezil ((S)-E2020 free base) 142057-80-5 (S)-Donepezil is the R-enantiomer of Donepezil.
(S)-Ladostigil V97126 (S)-Ladostigil 209394-29-6 (S)-Ladostigil (TV-3279) is the S-enantiomer of TV 3326, a ChE inhibitor with weak inhibitory activity against MAO-B.
(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) V71615 (±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) 2504-11-2 (±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist/activator with cholinergic properties.
1,10-Bis(pyridinium)decane V106966 1,10-Bis(pyridinium)decane 6266-40-6 1,10-Bis(pyridine)decane is an acetylcholinesterase (AchE) inhibitor with IC50 of 25.8nM.
1,2-Didehydrotanshinone IIA V103718 1,2-Didehydrotanshinone IIA 119963-50-7 1,2-Didehydrotanshinone IIA is a moderate inhibitor of AChE and BChE with IC50 of 5.98 μM for BChE.
2'-O-Succinyl-cAMP V71645 2'-O-Succinyl-cAMP 36940-87-1 2'-O-Succinyl-cAMP, a cAMP analog, can be covalently coupled to acetylcholinesterase.
3β-Hydroxy-lup-20(29)-en-16-one V71631 3β-Hydroxy-lup-20(29)-en-16-one 65043-60-9 3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual (bifunctional) inhibitor of AChE and BChE, with selectivity for BChE (IC50= 28.9 μM).
4-Hydroxyisophthalic acid V105589 4-Hydroxyisophthalic acid 636-46-4 4-Hydroxyisophthalic acid can activate antioxidant enzymes (such as catalase CAT and superoxide dismutase SOD), scavenge free radicals and exert antioxidant effects.
4-Methylbenzylidene camphor-d4 V71651 4-Methylbenzylidene camphor-d4 1219806-41-3 4-Methylbenzylidene camphor-d4 is the deuterated form of 4-Methylbenzylidene camphor.
6,9-Dichloro-1,2,3,4-tetrahydroacridine V106754 6,9-Dichloro-1,2,3,4-tetrahydroacridine 5396-25-8 6,9-Dichloro-1,2,3,4-tetrahydroacridine (Compound 26) is an intermediate in the synthesis of acetylcholinesterase (AChE) inhibitors and can be used in the study of Alzheimer's disease.
7-Acetoxy-1-methylquinolinium iodide (AMQI) V71630 7-Acetoxy-1-methylquinolinium iodide (AMQI) 7270-83-9 7-Acetoxy-1-methylquinolinium iodide (AMQI) is a fluorescent substrate for cholinesterase (Ex = 320 nm, Em = 410 nm).
Acacetin-7-O-β-D-galactopyranoside V71679 Acacetin-7-O-β-D-galactopyranoside 80443-15-8 Acacetin-7-O-β-D-galactopyranoside is a flavonoid that can be extracted from the flower heads of Chrysanthemum morifolium.
Acephate (acephate; acephate) V71681 Acephate (acephate; acephate) 30560-19-1 Acephate is a broad-spectrum anticholinesterase insecticide.
Acetylcholinesterase (ACHE; EC 3.1.1.7) V71613 Acetylcholinesterase (ACHE; EC 3.1.1.7) 9000-81-1 Acetylcholinesterase (ACHE; EC 3.1.1.7), acetylcholinesterase, is a cholinergic enzyme that mainly exists in neuromuscular junctions and cholinergic type chemical synapses and is widely utilized in biochemical research.
Acetylcholinesterase, Electric eel V107941 Acetylcholinesterase, Electric eel 9000-81-1 Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research.
Contact Us
Tel: 1-708-310-1919 Fax: 1-708-557-7486 Email: sales@invivochem.com Frequently Asked Questions
Subscribe to our E-newsletter
Name
E-mail

Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved

linkedin facebook
Contact Us
Home Product Cart Member