Na+K+ ATPase

Na+K+ ATPase

All higher eukaryotes contain a transmembrane protein complex called Na+/K+ ATPase, which serves as a vital energy-intensive pump that keeps ionic and osmotic balance in cells. Na+/K+ ATPase is a newly discovered cancer target that needs more research.

For re-establishing and maintaining this gradient, the Na+/K+-ATPase (NKA, or Na+ pump) must always be active. The main NKA isoforms in cardiac and vascular smooth muscle are isoforms 1 and 2, and their physiological roles are regulated by both their distinct subcellular distribution and their individual and independent signaling pathways.

Na+K+ ATPase related products

Structure Cat No. Product Name CAS No. Product Description
V1919 Chloroprocaine HCl 3858-89-7 Chloroprocaine HCl is a a potent, synthetic and local anesthetic used during surgical procedures.
V74209 Gitoxin 4562-36-1 Gitoxin is an inhibitor (blocker/antagonist) of Na+/K+-ATPase and a degradation metabolite of Digitoxin.
V84159 Oleandrigenin 465-15-6
V83410 Ouabagenin 508-52-1
V80318 Prilocaine acetate Prilocaine acetate is an aminoamide.
V4934 Rostafuroxin (PST 2238) 156722-18-8 Rostafuroxin (formerlyPST2238; PST-2238) is an ouabain andNa/K-ATPase antagonist with antihypertensive activities.
V50926 Sodium oleate (Oleic acid sodium) 143-19-1 Sodium oleate (sodium oleate) is the most common monounsaturated fertilizer sodium salt found in human fat cells and other tissues.
V74211 SPAI-1 131359-77-8 SPAI-1 is a specific inhibitor of monovalent cationic ATPase.
V74208 Stauntosaponin A (Stauntoside C) 1417887-91-2 Stauntosaponin A, a steroidal glycoside compound, is a potent Na(+)/K(+)-ATPase inhibitor (IC50=21 nM).
V74210 Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) 888486-23-5 Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a polypeptide consisting of 11 amino acid (AA)s, which can bind to Na+/K+-ATPase beta-subunit (ATP1B1) and mainly interacts with the C-terminus of ATP1B1.
V76399 Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a polypeptide consisting of 11 amino acid (AA)s that can bind to Na+/K+-ATPase beta-subunit (ATP1B1) and mainly interacts with the C-terminus of ATP1B1.
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