| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V128000 | AAK1-IN-10 | 3083494-45-2 | AAK1-IN-10 is an AAK1 inhibitor. |
|
V120107 | AAK1-IN-11 | AAK1-IN-11 is an AAK1 (adaptor protein-associated kinase 1) inhibitor with an IC50 of 2 nM. | |
|
V128001 | AAK1-IN-12 | 2892117-23-4 | AAK1-IN-12 is a selective, orally effective AAK1 inhibitor that can cross the blood-brain barrier. |
|
V71234 | AAK1-IN-2 TFA | 2761587-28-2 | AAK1-IN-2 TFA (compound (S)-31) is a specific, and BBB (blood-brain barrier) permeable (penetrable) AAK1 inhibitor (antagonist) with IC50 of 5.8 nM. |
|
V71233 | AAK1-IN-3 TFA | 2761587-27-1 | AAK1-IN-3 TFA is a quinoline analogue and a BBB (blood-brain barrier) permeable (penetrable) adapter protein 2-associated kinase 1 (AAK1) inhibitor (antagonist) with IC50 of 11 nM. |
|
V103665 | AAK1-IN-6 | AAK1-IN-6 (Compound 23) is an inhibitor of AP-2-associated protein kinase 1 (AAK1, IC50 = 12 nM) with antiviral activity against dengue virus (DNEV2, EC50 = 0.24 μM) and Venezuelan equine encephalitis virus (VEEV, EC50 = 0.30 μM). | |
|
V128004 | AAK1-IN-9 | AAK1-IN-9 is an AAK1 (adaptor protein-associated kinase 1) inhibitor with an IC50 of 10.92 nM. | |
|
V71232 | BMS-911172 | 1644248-18-9 | BMS-911172 is an AAK1 kinase inhibitor (IC50 = 35 nM). |
|
V3494 | BMS-986176 | 1815613-42-3 | BMS-986176 (LX-9211) is a potent, selective, BBB (blood-brain barrier)-crossing AAK1 (adaptor associated kinase 1) inhibitor (antagonist) with IC50 of 2 nM. |
|
V130417 | BMT-124110 formic | BMT-124110 formic is a potent and selective AAK1 inhibitor with an IC50 of 0.9 nM. | |
|
V137644 | HW161023 | 2920698-73-1 | HW161023 is an orally effective inhibitor of AP2-associated protein kinase 1 (AAK1), with IC50 values of 5.4 nM and 11.9 μM for AAK1 and hERG, respectively. |
|
V76811 | LP-922761 hydrate | LP-922761 hydrate is a specific, orally bioactive AAK1 inhibitor (antagonist) with IC50 of 4.8 nM and 7.6 nM in enzymatic and cellular assays, respectively. | |
|
V143243 | PROTAC AAK1 degrader-1 | 3113123-63-7 | PROTAC AAK1 degrader-1 is a selective PROTAC AAK1 degrader with a DC50 value of less than 10 nM. |