| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V120107 | AAK1-IN-11 | AAK1-IN-11 is an AAK1 (adaptor protein-associated kinase 1) inhibitor with an IC50 of 2 nM. | |
|
V71234 | AAK1-IN-2 TFA | 2761587-28-2 | AAK1-IN-2 TFA (compound (S)-31) is a specific, and BBB (blood-brain barrier) permeable (penetrable) AAK1 inhibitor (antagonist) with IC50 of 5.8 nM. |
|
V71233 | AAK1-IN-3 TFA | 2761587-27-1 | AAK1-IN-3 TFA is a quinoline analogue and a BBB (blood-brain barrier) permeable (penetrable) adapter protein 2-associated kinase 1 (AAK1) inhibitor (antagonist) with IC50 of 11 nM. |
|
V103665 | AAK1-IN-6 | AAK1-IN-6 (Compound 23) is an inhibitor of AP-2-associated protein kinase 1 (AAK1, IC50 = 12 nM) with antiviral activity against dengue virus (DNEV2, EC50 = 0.24 μM) and Venezuelan equine encephalitis virus (VEEV, EC50 = 0.30 μM). | |
|
V71232 | BMS-911172 | 1644248-18-9 | BMS-911172 is an AAK1 kinase inhibitor (IC50 = 35 nM). |
|
V3494 | BMS-986176 | 1815613-42-3 | BMS-986176 (LX-9211) is a potent, selective, BBB (blood-brain barrier)-crossing AAK1 (adaptor associated kinase 1) inhibitor (antagonist) with IC50 of 2 nM. |
|
V76811 | LP-922761 hydrate | LP-922761 hydrate is a specific, orally bioactive AAK1 inhibitor (antagonist) with IC50 of 4.8 nM and 7.6 nM in enzymatic and cellular assays, respectively. |