The G-protein-coupled receptors are a subfamily of seven-transmembrane cell surface receptors called prostaglandin receptors. Currently, ten prostaglandin receptors on various cell types are known. G-protein-coupled receptors are a subfamily of seven-transmembrane cell surface receptors that prostaglandins bind to. They are designated as DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, and TP-TP receptors. The prostaglandins are a class of lipid compounds with hormone-like properties that are produced enzymatically from fatty acids and serve significant roles in animal bodies. Currently, ten prostaglandin receptors on various cell types are known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V11670 | Asapiprant (S-555739) | 932372-01-5 | Asapiprant (S555739) is a novel, potent and selective Prostaglandin D2receptor 1 (DP1) receptor antagonist (Ki= 0.44 nM) with the potential for treating allergic airway diseases. |
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V8461 | Selexipag | 475086-01-2 | Selexipag (NS-304; NS304; ACT-293987; ACT293987;Uptravi) is a novel and potent prodrug ofACT-333679 (MRE-269) acting asnon-prostanoid IP receptor agonist and has been approved as a medication for the treatment of pulmonary arterial hypertension. |
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