The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V111575 | (+)-Niguldipine | 113165-32-5 | (+)-Nicotilpine is a potent dual inhibitor that targets L-type Ca2+ channels (Ki=85 pM) and α₁-adrenergic receptors (Ki=52 pM). |
|
V102163 | (+)-Niguldipine hydrochloride | 113145-69-0 | (+)-Niguldipine hydrochloride is a calcium channel antagonist. |
|
V71512 | (-)-Denudatin B (Denudatin B) | 87402-88-8 | (-)-Denudatin B has antiplatelet effects and inhibits Ca2+ influx through voltage-gated and receptor-regulated Ca2+ channels, thereby relaxing vascular smooth muscle. |
|
V71500 | (-)-Praeruptorin A | 14017-71-1 | (-)-Praeruptorin A is a naturally occurring compound extracted from the roots of Peucedanum praeruptorum Dunn. |
|
V84162 | (17R,18S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EETeTr) | 725246-18-4 | |
|
V77432 | (R)-Clevidipine-13C,d3 (Clevidipine 13C,d3) | (R)-Clevidipine-13C,d3 is the deuterated form of 13C (carbon 13)-labeled Clevidipine. | |
|
V71521 | (R)-IDHP | 950665-05-1 | (R)-IDHP is an isomer of IDHP. |
|
V112054 | (R)-Niguldipine | 120054-86-6 | (R)-Nicotidipine is the R-epiderm of nicotidipine and is a calcium channel antagonist. |
|
V118627 | (R)-Nimodipine | 77940-92-2 | (R)-Nimodipine ((R)-BAY-e 9736) is the corresponding isomer of nimodipine. |
|
V77439 | (Rac)-Benidipine-d7 | (Rac)-Benidipine-d7 is the deuterated form of Benidipine. | |
|
V96761 | (rel)-Mirogabalin | 1138244-97-9 | (rel)-Mirogabalin ((rel)-DS5565) is a voltage-dependent calcium channel inhibitor targeting the α2δ-1 subunit. |
|
V111250 | (S)-(-)-Felodipine | 105618-03-9 | (S)-(-)-Felodipine is the S-enantiomer of felodipine. |
|
V113145 | (S)-Albuterol hydrochloride | 50293-91-9 | Salbutamol hydrochloride (S)-salbutamol is a muscarinic receptor and phospholipase C activator. |
|
V117241 | (S)-Nimodipine | 77940-93-3 | (S)-Nimodipine ((S)-BAY-e 9736) is the corresponding isomer of nimodipine. |
|
V71478 | 1,2,4-Trihydroxybenzene (1,2,4-Trihydroxybenzene) | 533-73-3 | 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is a by-product of coffee bean roasting and can increase Ca2+ concentration in rat thymus lymphocytes. |
|
V104603 | 1,4-Dihydropyridine | 1,4-Dihydropyridine is a calcium channel antagonist that can block L-type calcium channels and reduce the influx of calcium ions into the heart and vascular smooth muscle cells, thereby reducing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure. | |
|
V92210 | 2-Chloro-ATP sodium | 301334-89-4 | 2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP. |
|
V84034 | 5,6-DiHETE | 845673-97-4 | |
|
V101510 | 8-Br-7-CH-cADPR | 189876-06-0 | 8-Br-7-CH-cADPR (7-Deaza-8-bromo-cADPR) is a potent cADPR antagonist. |
|
V77298 | Acetylcholine-d13 bromide (ACh-d13 bromide) | Acetylcholine-d13 (bromide) is the deuterated form of Acetylcholine bromide. |
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