The ion channel known as the calcium channel exhibits selective permeability to calcium ions. Although there are ligand-gated calcium channels as well, it is sometimes referred to as a voltage-dependent calcium channel. Even though the concentration of Na+ outside of cells is 70 times higher than that of Ca2+, voltage-gated calcium (CaV) channels catalyze a rapid, highly selective influx of Ca2+ into cells. A side effect of some calcium channel blockers is that they slow your heart rate, which helps to lower blood pressure, treat angina, and regulate irregular heartbeats.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71512 | (-)-Denudatin B (Denudatin B) | 87402-88-8 | (-)-Denudatin B has antiplatelet effects and inhibits Ca2+ influx through voltage-gated and receptor-regulated Ca2+ channels, thereby relaxing vascular smooth muscle. |
|
V71500 | (-)-Praeruptorin A | 14017-71-1 | (-)-Praeruptorin A is a naturally occurring compound extracted from the roots of Peucedanum praeruptorum Dunn. |
|
V84162 | (17R,18S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EETeTr) | 725246-18-4 | |
|
V77432 | (R)-Clevidipine-13C,d3 (Clevidipine 13C,d3) | (R)-Clevidipine-13C,d3 is the deuterated form of 13C (carbon 13)-labeled Clevidipine. | |
|
V71521 | (R)-IDHP | 950665-05-1 | (R)-IDHP is an isomer of IDHP. |
|
V77439 | (Rac)-Benidipine-d7 | (Rac)-Benidipine-d7 is the deuterated form of Benidipine. | |
|
V71478 | 1,2,4-Trihydroxybenzene (1,2,4-Trihydroxybenzene) | 533-73-3 | 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is a by-product of coffee bean roasting and can increase Ca2+ concentration in rat thymus lymphocytes. |
|
V84034 | 5,6-DiHETE | 845673-97-4 | |
|
V77298 | Acetylcholine-d13 bromide (ACh-d13 bromide) | Acetylcholine-d13 (bromide) is the deuterated form of Acetylcholine bromide. | |
|
V71528 | Agelenin | 142582-60-3 | Agelenin is a polypeptide consisting of 35 amino acid (AA)s. |
|
V77928 | Amlodipine-d4 besylate (Amlodipine benzenesulfonate-d4 besylate) | Amlodipine-d4 (besylate) is the deuterated form of Amlodipine besylate. | |
|
V87786 | ANO61 | 940476-20-0 | ANO61 is a dibenzylformamide derivative that exerts antiplatelet aggregation effects by modulating thrombin-induced Ca2+ responses with an IC50 of 47.7 μM. |
|
V77980 | Azelnidipine-d7 (Azelnidipine D7; CS-905-d7) | Azelnidipine-d7 is the deuterium labelled form of Azelnidipine. | |
|
V89927 | Azumolene sodium | 105336-14-9 | Azumolene sodium (EU4093) is a dantrolene analog that inhibits Halothane/Succinylcholine-induced malignant hyperthermia (MH) syndrome and intracellular Ca2+ homeostasis failure. |
|
V78345 | Barnidipine-d5 hydrochloride (Mepirodipine-d5 hydrochloride; YM-09730-5-d5 hydrochloride) | Barnidipine-d5 ( HCl) is the deuterated form of Barnidipine HCl. | |
|
V71473 | Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate; Org 5730 hydrochloride hydrate) | 74764-40-2 | Bepridil HCl hydrate ((±)-Bepridil HCl hydrate) is a non-selective, long-acting calcium ion channel (Ca+ channel) antagonist, sodium ion, potassium ion channel (Na+, K+ channel) inhibitor, with anti-angina and anti-anginal properties. |
|
V78576 | Butamben-d9 (Butyl 4-aminobenzoate-d9) | Butamben-d9 is the deuterated form of Butamben. | |
|
V71540 | Calciceptin | 178805-91-9 | Calciceptine, a natural neurotoxin extracted from the black mamba Dendroaspis p. polylepis. |
|
V71492 | Calcicludine | 178036-64-1 | Calcicludine is a protein toxin derived from the venom of the green mamba snake Dendroaspis angusticeps. |
|
V71541 | Calcium Channel antagonist 2 | 874370-15-7 | Calcium Channel antagonist 2 (Compound 154) is a calcium channel antagonist (IC50=5-20 μM), which can be used for Ca2+ channel-mediated diseases, such as pain and diabetes. |
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