Tyrosinase is a copper-containing metalloprotein belonging to the type-3 copper protein family, together with haemocyanins and catechol oxidases.Tyrosinases are the mammalian enzymes that initiate the production of melanin, the pigment that gives skin and hair their color, as well as the browning of fruits and vegetables after cell damage.
Tyrosinases are involved in pigmentation, wound healing, radiation protection, and the initial immune response. They are present in a variety of prokaryotes in addition to plants, fungi, arthropods, and mammals. The hydroxylation of monophenols and the oxidation of diphenols by tyrosinases results in quinones, which spontaneously polymerize to form melanin. Tyrosinases are crucial for wound healing and basic immune responses in plants, sponges, and a variety of invertebrates; they also aid in sclerotization in arthropods; and they shield DNA from UV ray damage in bacteria.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71954 | (-)-Taxifolin ((-)-Dihydroquercetin; (-)-Dihydroquercetin) | 111003-33-9 | (-)-Taxifolin is the less active isomer of Taxifolin. |
|
V71939 | 2-Methoxycinnamic acid | 6099-03-2 | 2-Methoxycinnamic acid is a noncompetitive tyrosinase inhibitor. |
|
V71935 | 3-O-Ethyl-L-ascorbic acid (vitamin C ethyl ether) | 86404-04-8 | 3-O-Ethyl-L-ascorbic acid, a stable vitamin C analogue, is a cosmetic tyrosinase inhibitor (antagonist) with whitening ability. |
|
V71962 | 4-Ethylresorcinol | 2896-60-8 | 4-Ethylresorcinol is an analogue of resorcinol that serves as a substrate for tyrosinase. |
|
V51532 | 5-epi-Arvestonate A | 2767066-84-0 | 5-epi-Arvestonate A is a sesquiterpenoid extracted from Seriphidium transiliense. |
|
V71937 | 5-Feruloylquinic acid | 40242-06-6 | 5-Feruloylquinic acid (5-FQA) has antioxidant and tyrosinase inhibitory activities. |
|
V71945 | 6-Hydroxykaempferol | 4324-55-4 | 6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor (antagonist) with IC50 of 124 μM. |
|
V71946 | 7-Methoxy obtusifolin | 1820806-09-4 | 7-Methoxy obtusifolin (Compound 4) is a competitive tyrosinase inhibitor (antagonist) with IC50 of 7.0 μM. |
|
V71949 | Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 | 82188-67-8 | Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 is a melanogen, a hormone that stimulates melanocytes. |
|
V71963 | Allamadicin | 51838-83-6 | Allamadicin is an iridoid lactone. |
|
V71944 | Azo-resveratrol | 1393556-48-3 | Azo-resveratrol is an azo compound that can inhibit mushroom tyrosinase (IC50=36.28 μM). |
|
V71932 | Broussonin C | 76045-49-3 | Broussonin C is a competitive inhibitor of Tyrosinase and can be extracted from Broussonetia kazinoki. |
|
V71956 | Chlorogenic acid butyl ester | 132741-56-1 | Chlorogenic acid butyl ester is a caffeoylquinic acid, a potent melanogenesis inhibitor. |
|
V71941 | Cyclocommunol | 145643-96-5 | Cyclocommunol is an amyl flavonoid with antityrosinase and antiplatelet activity extracted from breadfruit. |
|
V71964 | Diaminopropionoyl tripeptide-33 | 1199495-15-2 | Diaminopropionoyl tripeptide-33 is a biologically active peptide that has the effect of protecting skin cells from UVA-induced DNA damage and has been reported for use as a cosmetic ingredient. |
|
V71952 | Dodoviscin A | 1372527-25-7 | Dodoviscin A is a pigmentation-altering agent extracted from the aerial parts of Dodonaea viscosa. |
|
V71965 | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid | 57719-81-0 | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is a tyrosinase inhibitor against melanin synthesis that can be extracted from Pteris fern. |
|
V71943 | Flanvotumab (IMC-20D7S) | 1188277-05-5 | Flanvotumab (IMC-20D7S) is a human monoclonal antibody (mAb) targeting tyrosinase-related protein (TYRP1), which is specifically expressed on melanocytes and melanoma cells. |
|
V71947 | hTYR/AbTYR-IN-1 | 1625821-37-5 | hTYR/AbTYR-IN-1 (Compound 7) is a hTYR/AbTYR dual (bifunctional) inhibitor (antagonist) with IC50 of 5.4 μM and 3.52 μM for hTYR and AbTYR, respectively. |
|
V71942 | Isolindleyin | 87075-18-1 | Isolindleyin is a butyrophenone and a tyrosinase inhibitor (antagonist) with a Kd of 54.8 μM for human tyrosinase. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
