yingweiwo
  1. Home
  2. Products
  3. Signaling Pathways
  4. Cytoskeletal Signaling
  5. Dynamin

Dynamin

Dynamin

Dynamins are large superfamily GTPase proteins that are involved in various cellular processes including budding of transport vesicles, division of organelles, cytokinesis, and pathogen resistance. Eukaryotic cells use dynamins to scissor (cleave the vesicle from the parent membrane) developing vesicles from parent membranes. Dynamins sever and release coated vesicles by directly interacting with the lipid bilayer at the necks of clathrin-coated pits. While dynamin-related proteins (DRPs) lack one or more of these domains or have additional domains, dynamins have five domains, including the GTPase domain, middle domain, PH domain, GTPase effector domain (GED), and proline rich domain (PRD).Several different cellular processes, such as cytokinesis and membrane fission in plant cells (Arabidopsis thalianaDRP proteins), pathogen resistance, vacuolar fission in yeast (Saccharomyces cerevisiae Vps1), and interferon-induced antiviral protection (fish Mx proteins) are all regulated by dynamins and DRPs.

Dynamin related products

Structure Cat No. Product Name CAS No. Product Description
Clathrin-IN-2 V52244 Clathrin-IN-2 2650733-69-8 Clathrin-IN-2 is a potent inhibitor of clathrin-mediated endocytosis (CME) with IC50 of 2.3 μM.
Clathrin-IN-4 V56038 Clathrin-IN-4 762242-59-1 Clathrin-IN-4 (compound 8b) is an analogue of Wiskostatin , a potent clathrin-mediated endocytosis (endocytosis) inhibitor (antagonist) with IC50 of 2.1 μM.
DRP1 Allosteric-IN-1 V113199 DRP1 Allosteric-IN-1 1359386-11-0 DRP1 allosteric inhibitor-IN-1 (compound 1) is a DRP1 allosteric inhibitor with an IC50 value of 3.6 μM for the DRP1:MiD49 protein-protein interaction.
DRP1 Allosteric-IN-2 V113247 DRP1 Allosteric-IN-2 3056559-91-9 DRP1 allosteric inhibitor-IN-2 (compound 2a) is an allosteric inhibitor of DRP1 with an IC50 value of 4.3 μM for the DRP1:MiD49 protein-protein interaction.
DRP1 Allosteric-IN-3 V113173 DRP1 Allosteric-IN-3 3056559-92-0 DRP1 allosteric inhibitor-IN-3 (compound 2b) is a DRP1 allosteric inhibitor with an IC50 value of 11 μM for the DRP1:MiD49 protein-protein interaction.
Drp1 peptide inhibitor P110 V106367 Drp1 peptide inhibitor P110 2770267-63-3 Drp1 peptide inhibitor P110 (compound P110) is a selective Drp1 peptide inhibitor with neuroprotective effects.
Drp1 peptide inhibitor P110 TFA V112439 Drp1 peptide inhibitor P110 TFA Drp1 peptide inhibitor P110 (compound P110) TFA is a selective Drp1 peptide inhibitor with neuroprotective effects.
DRP1i27 V52158 DRP1i27 1453028-33-5 DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1).
DRP1i27 dihydrochloride V77065 DRP1i27 dihydrochloride DRP1i27 di-HCl is a potent inhibitor of human Drp1 (dynamin-related protein 1).
Dynamin IN-1 V56040 Dynamin IN-1 1345853-50-0 Dynamin IN-1 is a potent dynamin inhibitor (antagonist) with IC50 of 1.0 µM.
Dynamin IN-2 V56039 Dynamin IN-2 1345853-49-7 Dynamin IN-2 (compound 43), a Wiskostatin analogue, is a potent dynamin inhibitor against dynamin I GTPase The IC50 is 1.0 μM.
Dynamin inhibitory peptide V52149 Dynamin inhibitory peptide 251634-21-6 Dynamin inhibitory peptide competitively blocks the binding of dynamin to amphoteric fibrin, thereby preventing endocytosis.
Dynamin inhibitory peptide TFA V79228 Dynamin inhibitory peptide TFA Dynamin inhibitory peptide TFA competitively blocks the binding of dynamin to amphoteric fibrin, thereby preventing endocytosis.
DynaMin inhibitory peptide, myristoylated V56037 DynaMin inhibitory peptide, myristoylated 251634-22-7 DynaMin inhibitory peptide, myristoylated is a DynaMin inhibitor that interferes with the binding of amphotericin (amphiphysin) and dynamin (dynamin).
DynaMin inhibitory peptide, myristoylated TFA V79229 DynaMin inhibitory peptide, myristoylated TFA DynaMin inhibitory peptide, myristoylated TFA is a DynaMin inhibitor that interferes with the binding of amphotericin (amphiphysin) and dynamin (dynamin).
Dynapyrazole-A V52148 Dynapyrazole-A 2226517-75-3 Dynapyrazole A is a specific inhibitor of microtubule dynein that specifically inhibits the ATPase activity of microtubule-stimulated dynein but does not block the microtubule-independent basal activity.
Dyngo-4a V1592 Dyngo-4a 1256493-34-1 Dyngo-4a (Dyngo 4a; Hydroxy Dynasore) is a potent and novel dynamin inhibitor with the potential to treatbotulism.
Dynole 2−24 V53404 Dynole 2−24 1416313-72-8 Dynole 2-24 is an indole-based dynamin GTPase inhibitor (IC50 for dynamin I=0.56 μM).
Dynole 34-2 V51316 Dynole 34-2 1128165-88-7 Dynole 34-2 is a dynamin GTPase (IC50 for dynamin 1 and dynamin 2 GTPase activity of 6.9 and 14.2 µM, respectively) with antimitotic effects.
IIQLPEIVVV TFA V94367 IIQLPEIVVV TFA IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction.
Contact Us
Tel: 1-708-310-1919 Fax: 1-708-557-7486 Email: sales@invivochem.com Frequently Asked Questions
Subscribe to our E-newsletter
Name
E-mail

Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved

linkedin facebook
Contact Us
Home Product Cart Member