| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V5070 | ESI-05 (NSC 116966) | 5184-64-5 | ESI-05 (also known as NSC 116966) is a novel, potent and specific antagonist of EPAC2 (exchange protein directly activated by cAMP 2), with an IC50 of 0.4 µM. |
|
V1481 | Forskolin (Coleonol; Colforsin) | 66575-29-9 | Forskolin (HL-362; L-75-1362B; NSC-357088; NSC-375489; Coleonol; Colforsin), a naturally occurring and cell-permeable diterpene extracted from the Indian Coleus plant (C. forskohlii), is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types. |
|
V22213 | HJC0197 | 1383539-73-8 | HJC0197 (HJC-0197) is a novel and potent EPAC (erythromycin propionate-N-acetylcysteinate) inhibitor and an Epac2 antagonist (IC50=5.9 μM for Epac2) with anticancer activity. |
|
V1924 | HJC0350 | 885434-70-8 | HJC0350 is a potent and selective antagonist/inhibitor of EPAC2 with IC50 of 0.3 μM, it exhibited no inhibition on Epac1. |
|
V2075 | PACAP 1-27 | 127317-03-7 | PACAP 1-27 (HSDGIFTDSYSRYRKQMAVKKYLAAVL),the N-terminal fragment of PACAP-38, is a pituitary adenylate cyclase activating polypeptide that acts as a potent PACAP receptor antagonist with IC50s of 3 nM, 2 nM and 5 nM for rat PAC1, rat VPAC1 and human VPAC2, respectively. |
|
V2752 | PACAP 1-38 | 137061-48-4 | PACAP 1-38 is a highly potent agonist of the PACAP (Pituitary adenylate cyclase-activating polypeptide) receptor with Kd of 100 pM. |
|
V2753 | PACAP 6-38 | 143748-18-9 | PACAP 6-38 is a novel and potent PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist with an IC50 value of 2 nM. |
|
V15282 | ST034307 | 133406-29-8 | ST034307 is a potent and specific inhibitor of adenylyl cyclase 1 with IC50 of 2.3 μM. |
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