The common herpesvirus family includes the double-stranded DNA virus known as cytomegalovirus (CMV). Cytomegaloviruses evade immune clearance and endure for the entirety of the infected host's life. However, the balance of this virus-host interaction is unstable and depends on the cellular immune response, which typically necessitates the activity of particular CD8 T lymphocytes.
The herpesvirus family, also known as the herpesviridae or human herpesvirus-5 (HHV-5), includes the human cytomegalovirus. Salivary glands and human cytomegalovirus infections are frequently linked. While CMV infection may not cause any symptoms in healthy individuals, it can be fatal in an immunocompromised patient. Congenital cytomegalovirus infection can be fatal or cause serious illness. CMV frequently remains dormant after infection, but it could reactivate at any time. It eventually results in mucoepidermoid carcinoma and is thought to be the cause of prostate cancer.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V111807 | Antiviral agent 37 | 357163-03-2 | Antiviral drug 37 (page 57) is a potent pUL97 inhibitor. |
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V88219 | BAY-43-9695 | 233255-39-5 | BAY-43-9695 is a non-nucleoside with anti-human cytomegalovirus (hCMV) activity with IC50 of 0.95 and 1.1 μM as measured by FACS and PRA, respectively. |
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V129957 | BDCRB | 142356-43-2 | BDCRB is a selective human cytomegalovirus (HCMV) inhibitor that works by blocking the maturation and cleavage of high molecular weight DNA. |
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V118757 | CBMicro_010679 | 349425-56-5 | CBMicro_010679 (compound 5) is a non-nucleoside antiherpes virus drug. |
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V131336 | CEF20 TFA | CEF20 TFA is the HLA-A*0201 restriction epitope of cytomegalovirus pp65 (495-503). | |
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V104233 | CMV-423 | 186829-19-6 | CMV-423 is an antiviral agent with potent in vitro activity against the betaherpesviruses human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6), and human herpesvirus 7 (HHV-7). |
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V88220 | DNA polymerase-IN-5 | DNA polymerase-IN-5 (compound 42) is a broad-spectrum anti-herpes virus drug. | |
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V136301 | Fomivirsen sodium scrambled negative control | The Fomivirsen sodium scrambled negative control is a negative control with the Fomivirsen sodium sequence scrambled. | |
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V136520 | Ganciclovir triphosphate disodium | Ganciclovir triphosphate disodium is a synthetic 2'-deoxyguanosine analogue with activity that inhibits the replication of human cytomegalovirus (CMV). | |
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V115319 | GW 275175X | 217950-62-4 | GW 275175X is a terminal enzyme complex inhibitor that participates in the cleavage and packaging of DNA per unit length, ultimately leading to its entry into the capsid. |
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V142878 | PMEG | 114088-58-3 | PMEG is an inhibitor of nuclear DNA polymerases α, δ, and ε that can cause DNA chain termination, inhibit DNA synthesis, and induce cytotoxicity in dividing cells. |
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V116313 | T-0902611 benzenesulfonate | 350595-61-8 | T-0902611 benzenesulfonate is a specific HCMV inhibitor. |
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V115281 | VTEHDTLLY | 481651-50-7 | VTEHDTLLY is an HLA class I restricted CMV peptide epitope. |
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V29193 | Ganciclovir | 82410-32-0 | Ganciclovir (2'-Nor-2'-deoxyguanosine, BW-759) is a novel and potent herpes simplex virus (HSV) inhibitor. |
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V21502 | Ganciclovir Sodium | 107910-75-8 | Ganciclovir sodium, an acyclovir analog,is a novel and potent antiviral drug used to treat or prevent cytomegalovirus (CMV) infections. |
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V14070 | Brivudine | 69304-47-8 | Brivudine (Brivox; Helpin ;Zerpex; BVDU; RP101;bromovinyl-deoxyuridine) is a novel and potent uridine analogue and nucleoside analoguewith pro-apoptotic and chemosensitizing activities. |
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V2459 | Valganciclovir HCl | 175865-59-5 | Valganciclovir HCl is the L-valyl ester prodrug of ganciclovir which is an antiviral drug used to treat cytomegalovirus infections. |