The common herpesvirus family includes the double-stranded DNA virus known as cytomegalovirus (CMV). Cytomegaloviruses evade immune clearance and endure for the entirety of the infected host's life. However, the balance of this virus-host interaction is unstable and depends on the cellular immune response, which typically necessitates the activity of particular CD8 T lymphocytes.
The herpesvirus family, also known as the herpesviridae or human herpesvirus-5 (HHV-5), includes the human cytomegalovirus. Salivary glands and human cytomegalovirus infections are frequently linked. While CMV infection may not cause any symptoms in healthy individuals, it can be fatal in an immunocompromised patient. Congenital cytomegalovirus infection can be fatal or cause serious illness. CMV frequently remains dormant after infection, but it could reactivate at any time. It eventually results in mucoepidermoid carcinoma and is thought to be the cause of prostate cancer.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V88219 | BAY-43-9695 | 233255-39-5 | BAY-43-9695 is a non-nucleoside with anti-human cytomegalovirus (hCMV) activity with IC50 of 0.95 and 1.1 μM as measured by FACS and PRA, respectively. | |
V88220 | DNA polymerase-IN-5 | DNA polymerase-IN-5 (compound 42) is a broad-spectrum anti-herpes virus drug. | ||
V29193 | Ganciclovir | 82410-32-0 | Ganciclovir (2'-Nor-2'-deoxyguanosine, BW-759) is a novel and potent herpes simplex virus (HSV) inhibitor. | |
V21502 | Ganciclovir Sodium | 107910-75-8 | Ganciclovir sodium, an acyclovir analog,is a novel and potent antiviral drug used to treat or prevent cytomegalovirus (CMV) infections. | |
V14070 | Brivudine | 69304-47-8 | Brivudine (Brivox; Helpin ;Zerpex; BVDU; RP101;bromovinyl-deoxyuridine) is a novel and potent uridine analogue and nucleoside analoguewith pro-apoptotic and chemosensitizing activities. | |
V2459 | Valganciclovir HCl | 175865-59-5 | Valganciclovir HCl is the L-valyl ester prodrug of ganciclovir which is an antiviral drug used to treat cytomegalovirus infections. |