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CMV

CMV

The common herpesvirus family includes the double-stranded DNA virus known as cytomegalovirus (CMV). Cytomegaloviruses evade immune clearance and endure for the entirety of the infected host's life. However, the balance of this virus-host interaction is unstable and depends on the cellular immune response, which typically necessitates the activity of particular CD8 T lymphocytes.
The herpesvirus family, also known as the herpesviridae or human herpesvirus-5 (HHV-5), includes the human cytomegalovirus. Salivary glands and human cytomegalovirus infections are frequently linked. While CMV infection may not cause any symptoms in healthy individuals, it can be fatal in an immunocompromised patient. Congenital cytomegalovirus infection can be fatal or cause serious illness. CMV frequently remains dormant after infection, but it could reactivate at any time. It eventually results in mucoepidermoid carcinoma and is thought to be the cause of prostate cancer.

CMV related products

Structure Cat No. Product Name CAS No. Product Description
Antiviral agent 37 V111807 Antiviral agent 37 357163-03-2 Antiviral drug 37 (page 57) is a potent pUL97 inhibitor.
BAY-43-9695 V88219 BAY-43-9695 233255-39-5 BAY-43-9695 is a non-nucleoside with anti-human cytomegalovirus (hCMV) activity with IC50 of 0.95 and 1.1 μM as measured by FACS and PRA, respectively.
BDCRB V129957 BDCRB 142356-43-2 BDCRB is a selective human cytomegalovirus (HCMV) inhibitor that works by blocking the maturation and cleavage of high molecular weight DNA.
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) V35042 Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 207226-35-5 Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a chelating agent and a useful antidote (eg, acute cadmium poisoning).
CBMicro_010679 V118757 CBMicro_010679 349425-56-5 CBMicro_010679 (compound 5) is a non-nucleoside antiherpes virus drug.
CEF20 TFA V131336 CEF20 TFA CEF20 TFA is the HLA-A*0201 restriction epitope of cytomegalovirus pp65 (495-503).
CMV-423 V104233 CMV-423 186829-19-6 CMV-423 is an antiviral agent with potent in vitro activity against the betaherpesviruses human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6), and human herpesvirus 7 (HHV-7).
DNA polymerase-IN-5 V88220 DNA polymerase-IN-5 DNA polymerase-IN-5 (compound 42) is a broad-spectrum anti-herpes virus drug.
Fomivirsen (ISIS-2922 free base) V54158 Fomivirsen (ISIS-2922 free base) 144245-52-3 Fomivirsen (ISIS-2922 free base) is an antisense 21 mer phosphothio-oligonucleotide.
Fomivirsen sodium scrambled negative control V136301 Fomivirsen sodium scrambled negative control The Fomivirsen sodium scrambled negative control is a negative control with the Fomivirsen sodium sequence scrambled.
Ganciclovir triphosphate disodium V136520 Ganciclovir triphosphate disodium Ganciclovir triphosphate disodium is a synthetic 2'-deoxyguanosine analogue with activity that inhibits the replication of human cytomegalovirus (CMV).
GW 275175X V115319 GW 275175X 217950-62-4 GW 275175X is a terminal enzyme complex inhibitor that participates in the cleavage and packaging of DNA per unit length, ultimately leading to its entry into the capsid.
PMEG V142878 PMEG 114088-58-3 PMEG is an inhibitor of nuclear DNA polymerases α, δ, and ε that can cause DNA chain termination, inhibit DNA synthesis, and induce cytotoxicity in dividing cells.
SB-734117 V54160 SB-734117 607368-97-8 SB-734117 is an inhibitor (blocker/antagonist) of human cytomegalovirus (HCMV) replication that prevents CREB and histone H3 post-translational modifications.
T-0902611 benzenesulfonate V116313 T-0902611 benzenesulfonate 350595-61-8 T-0902611 benzenesulfonate is a specific HCMV inhibitor.
Tricin-d6 V81615 Tricin-d6 Tricin-d6 is the deuterated form of Tricin.
Valganciclovir-d5 TFA (缬更昔洛韦-d5) V52560 Valganciclovir-d5 TFA (Valganciclovir-d5) 1402924-31-5 Valganciclovir-d5 (TFA) is the deuterated form of Valganciclovir TFA.
Valganciclovir-d8 hydrochloride (Valganciclovir-d8 hydrochloride) V52550 Valganciclovir-d8 hydrochloride (Valganciclovir-d8 hydrochloride) 1132088-63-1 Valganciclovir-d8 ( HCl) is the deuterium labelled form of Valganciclovir HCl.
VTEHDTLLY V115281 VTEHDTLLY 481651-50-7 VTEHDTLLY is an HLA class I restricted CMV peptide epitope.
托美洛韦 V4218 Tomeglovir 233254-24-5 Tomeglovir (also known as BAY-38-4766) is a novel, potent andnon-nucleoside anti-CMV (cytomegalovirus) agent which inhibits processing of viral DNA-concatemers withIC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
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