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V87536
|
Ebelactone A
|
76808-16-7 |
Ebelactone A is a mycolic acid β-lactone that has inhibitory activity against esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase with IC50 values of 56, 3, 8 and 7.5 μM, respectively. |
|
V1903
|
XEN445
|
1515856-92-4 |
XEN445 (XEN-445) is a novel, potent and selective endothelial lipase (EL) inhibitor (IC50 = 0.237 μM) with favorable ADME and PK properties, as well as in vivo efficacy in raising plasma HDLc concentrations in mice. |
|
V13134
|
Pristimerin
|
1258-84-0 |
Pristimerin (Celastrol-methylether; UNII-28ZK7PR57S) is a naturally occurringtriterpenoid, acting as areversible monoacylglycerol lipase (MGL) inhibitor (IC50 = 93 nM)with antitumor activity. |
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V3147
|
Cetilistat (ATL-962)
|
282526-98-1 |
Cetilistat (previously known as ATL-962) is a novel inhibitor of pancreatic and gastrointestinal lipases. |