Interleukin Related

Interleukin Related

White blood cells (leukocytes), which are a subset of cytokines (secreted proteins and signaling molecules), were the first to be observed to express interleukins. Interleukins are crucial for the immune system's proper operation, and there have been rare cases of their deficiency that have all been associated with autoimmune disorders or immune deficiencies. Helper CD4 T lymphocytes, along with monocytes, macrophages, and endothelial cells, produce the majority of interleukins. They support the growth and differentiation of hematopoietic cells, including T and B lymphocytes. The development of spatial memories in mice has also been linked to interleukin receptors on astrocytes in the hippocampus.

Interleukin Related related products

Structure Cat No. Product Name CAS No. Product Description
V75015 (R)-TCB2 912342-36-0 (R)-TCB2 is the R-enantiomer of TCB2.
V75016 12-Dehydrogingerdione (12-DHGD) 99742-05-9 12-Dehydrogingerdione is an inhibitor (blocker/antagonist) of NO Synthase.
V74366 4-Methoxylonchocarpin 51589-67-4 4-Methoxylonchocarpin is an orally bioactive anti-inflammatory agent.
V75031 Abrezekimab (UCB4144; VR 942) 2043952-59-4 Abrezekimab (VR 942) contains CDP7766, a humanized, high-affinity, neutralizing, anti-human IL-13 antibody fragment that binds IL-13.
V77789 Ac-YVAD-CHO acetate (L-709049 acetate) Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1β converting enzyme (ICE) inhibitor (antagonist) with Kis of 3.0 and 0.76 nM in mice and humans, respectively.
V75033 Acetyl hexapeptide-49 1969409-70-8 Acetyl hexapeptide-49 is a biologically active peptide with anti-sensitivity effects that has been reported as an ingredient of cosmetics.
V77816 ADR58 sodium ADR58 sodium is a potent and specific human oncostatin M (OSM) antagonist that blocks the binding of OSM to gp130 receptors and specifically antagonizes OSM-mediated signaling.
V74934 AF12198 185413-30-3 AF12198 is a specific and specific peptide antagonist against the human type I interleukin-1 receptor (IL1R1) (IC50=8 nM), but not against the human type II receptor (IC50=6.7 µM) or murine type I receptor (IC50>200 µM).
V75023 Afasevikumab (RG 7624; RO 5553110; NI-1401) 1589503-30-9 Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody that neutralizes IL-17A and IL-17F.
V74980 Anrukinzumab (IMA-638) 910649-32-0 Anrukinzumab (IMA-638) is a humanized antibody that can inhibit human IL-13.
V74954 Anti-Human IL-17A 1229022-83-6 Anti-Human IL-17A is a fully human anti-interleukin 17A monoclonal antibody (mAb).
V75009 Anti-inflammatory agent 42 877468-30-9 Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent.
V78017 Anti-inflammatory agent 58 Anti-inflammatory agent 58 is an anti-inflammatory agent that inhibits IL-1β with IC50 of 1.08 μM.
V78018 Anti-inflammatory agent 59 Anti-inflammatory agent 59 is an anti-inflammatory agent that inhibits IL-1β with IC50 of 2.28 μM.
V79927 Anti-inflammatory agent 64 Anti-inflammatory agent 64 (compound 4b) can inhibit the secretion of IL-6 and TNF-α.
V83378 Anti-inflammatory agent 74
V78043 Anti-Mouse IL-10 Antibody Anti-Mouse IL-10 Antibody is an IgG1 antibody inhibitor against mouse IL-10.
V78048 Anti-neuroinflammation agent 1 Anti-neuroinflammation agent 1 is a potent anti-neuroinflammation agent that modulates the polarization of BV2 microglia from the M1 to M2 phenotype.
V74941 Astegolimab (atelizumab; MSTT 1041A; RG 6149) 2173054-79-8 Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody (mAb) that blocks IL-33 signaling by targeting the IL-33 receptor ST2.
V74963 Avizakimab (BOS161721) 2229685-51-0 Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody (mAb) targeting interleukin-21 (IL-21).
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