Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptor superfamily ligand-activated transcription factors that include the following three subtypes: PPAR, PPAR, and PPAR/. Higher organisms' cellular differentiation, development, metabolism (carbohydrate, lipid, and protein), as well as tumorigenesis, are all crucially regulated by PPARs. All PPARs bind to particular regions of the target genes' DNA through heterodimerization with the retinoid X receptor (RXR). Triglyceride levels are reduced and energy homeostasis is regulated when PPAR- is activated. PPAR- activation improves the metabolism of glucose, whereas PPAR-/ activation improves the metabolism of fatty acids.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V104178 | (E/Z)-Elafibranor | 824932-88-9 | (E/Z)-Elafibranor ((E/Z)-GFT505) is a PPARα/δ agonist with EC50 of 45 and 175 nM, respectively. |
|
V90508 | (R)-Pioglitazone | 959687-65-1 | (R)-Pioglitazone ((+)-pioglitazone) is the R-isomer of pioglitazone. |
|
V51357 | (S)-Coriolic acid (13(S)-HODE) | 29623-28-7 | (S)-Coriolic acid (13(S)-HODE) is the endogenous ligand that activates PPARγ and is produced when linoleic acid is metabolized by 15-lipoxygenase (15-LOX). |
|
V103624 | (±)-CBCQ | 2415352-36-0 | (±)-CBCQ is an oxidative product of cannabidiol with an EC50 value of 14.7 μM for peroxisome proliferator-activated receptor γ (PPAR-γ). |
|
V107877 | 1,1'-(Azodicarbonyl)-dipiperidine | 10465-81-3 | 1,1'-Azodicarbonyldipiperidine (ADDP) can be used for the condensation reaction of alcohols and acidic compounds. It can also be used to synthesize GPR120 agonists with anti-diabetic activity, as well as to synthesize PPARα, PPARγ, and PPARδ triple agonists, which can be used in the study of metabolic diseases. |
|
V84017 | 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine (SDPC; DHA-PC; 18:0/22:6 PC) | 59403-52-0 | |
|
V51337 | 10-Nitrolinoleic acid | 774603-04-2 | 10-Nitrolinoleic acid is a novel agonist for the peroxisome proliferator-activated receptor γ (PPARγ). |
|
V51360 | 13-Oxo-9E,11E-octadecadienoic acid | 29623-29-8 | 13-Oxo-9E,11E-octadecadienoic acida an isomer of 9-oxo-ODA, is a novel and selective PPARα activator derived from tomato juice. |
|
V84085 | 17(S)-HDHA | 92693-03-3 | |
|
V101027 | 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid | 1233715-28-0 | 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid (17-Oxo-DHA) is an oxidative metabolite of DHA mediated by lipoxygenase. |
|
V101279 | 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid | 1233715-33-7 | 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-oxo-DPA; 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo derivative (EFOX) of docosahexaenoic acid (DHA). |
|
V83583 | 20-Carboxyarachidonic acid | 79551-84-1 | |
|
V52518 | 23-epi-26-Deoxyactein (27-Deoxyactein) | 501938-01-8 | 23-epi-26-Deoxyactein is a natural, orally biologically active compound with anti-obesity and anti-tumor effects. |
|
V88749 | 25-Hydroxytachysterol3 | 39932-44-0 | 25-Hydroxytachysterol3 is a metabolite of Vitamin D3. |
|
V88754 | 3-Thiatetradecanoic acid | 116296-31-2 | 3-Thiatetradecanoic acid is a substrate for N-myristoyltransferase (NMT), which is involved in the metabolism of thia-fatty acids. |
|
V84134 | 4,5-DiHDPA lactone | 845673-68-9 | |
|
V84426 | 5-Aminosalicylic acid-13C6 hydrochloride (Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride) | 1261398-47-3 | |
|
V104343 | 9(10)-Nitrooleate | 1092676-99-7 | 9(10)-Nitrooleate (9(10)-nitrooleic acid) is a nitro derivative of oleic acid. |
|
V84137 | 9-HEPE | 286390-03-2 | |
|
V107063 | 9-Octadecynoic acid | 506-24-1 | 9-Octadecynoic acid is a DNA binding agent with a dissociation constant of 1.8 mM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
