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Fungal

Fungal

A drug known as an antifungal agent selectively removes fungal pathogens from a host with little harm to the host. Classes: 1. Polyene antifungal medications: Amphotericin, nystatin, and pimaricin interact with the cell membrane's sterols (ergosterol in fungi, cholesterol in people) to create channels that allow small molecules to escape the inside of the fungal cell and enter the surrounding environment. 2. Azole antifungal medications: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes, particularly C14-demethylase, which are involved in the biosynthesis of ergosterol, a substance necessary for the structure and operation of fungal cell membranes. 3. Morpholine and allylamine antifungal medications: Squalene epoxidase is the enzyme that lylamines (naftifine, terbinafine) inhibit. At a later stage, the morpholine drug amorolfine inhibits the same pathway. 4. Antifungal Antimetabolite Drugs: Because 5-fluorocytosine is converted to 5-fluorouracil intracytoplasmically, it inhibits the synthesis of both DNA and RNA.

Fungal related products

Structure Cat No. Product Name CAS No. Product Description
(+)-Pinoresinol diacetate V76266 (+)-Pinoresinol diacetate 32971-25-8 (+)-Pinoresinol diacetate is a naturally occurring compound extracted from Sambucus williamsii and has antifungal activity.
(-)-Bornyl acetate ((-)-乙酸龙脑酯; L-(-)-Bornyl acetate) V35082 (-)-Bornyl acetate ((-)-bornyl acetate; L-(-)-Bornyl acetate) 5655-61-8 (-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active isomer of (+)-Bornyl acetate found in hyssop oil.
(2R,4S)-Hydroxy Itraconazole-d5 ((2R,4S)-R-63373-d5) V56258 (2R,4S)-Hydroxy Itraconazole-d5 ((2R,4S)-R-63373-d5) 1217524-77-0 (2R,4S)-Hydroxy Itraconazole-d5 is the deuterium labelled form of (2R,4S)-Hydroxy Itraconazole.
(2R,4S)-Hydroxy Itraconazole-d8 ((2R,4S)-R-63373-d8) V56366 (2R,4S)-Hydroxy Itraconazole-d8 ((2R,4S)-R-63373-d8) 1217516-26-1 (2R,4S)-Hydroxy Itraconazole-d8 is the deuterium labelled form of (2R,4S)-Hydroxy Itraconazole.
(E)-β-Farnesene (trans-β-Farnesene) V76259 (E)-β-Farnesene (trans-β-Farnesene) 18794-84-8 (E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon present in Phlomis aurea Decne essential oil.
(Rac)-Paclobutrazol-15N3 V56367 (Rac)-Paclobutrazol-15N3 2642083-16-5 (Rac)-Paclobutrazol-15N3 is 15N labeled Rac-Paclobutrazol.
(S,S)-Valifenalate ((S,S)-IR5885; (S,S)-Valiphenal) V52916 (S,S)-Valifenalate ((S,S)-IR5885; (S,S)-Valiphenal) 283159-94-4 (S,S)-Valifenalate ((S,S)-IR5885) is an amic acid fungicide used to inhibit various fungi of the class Oomycetes.
(Z)-Fluoxastrobin V53979 (Z)-Fluoxastrobin 887973-21-9 (Z)-Fluoxastrobin is a fungicide.
(Z)-Lanoconazole V53060 (Z)-Lanoconazole 101529-65-1 (Z)-Lanoconazole is the Z configuration form of Lanoconazole.
(±)-Pinoresinol V52841 (±)-Pinoresinol 4263-88-1 (±)-Pinoresinol is a potent antifungal compound/agent.
1,3,6-Trihydroxy-5-methoxyxanthone V53960 1,3,6-Trihydroxy-5-methoxyxanthone 41357-84-0 1,3,6-Trihydroxy-5-methoxyxanthone is a naturally occurring compound that can be extracted from the root bark of Tovomita krukovii.
1-Dodecylimidazole (N-Dodecylimidazole) V41079 1-Dodecylimidazole (N-Dodecylimidazole) 4303-67-7 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomally active detergent and cytotoxic agent.
1-O-Methylemodin V53927 1-O-Methylemodin 3775-08-4 1-O-Mmethylemodin is a naturally occurring compound extracted from Zopfiella longicaudata.
1-Phenylsemicarbazide (2-phenylhydrazinecarboxamide) V53928 1-Phenylsemicarbazide (2-phenylhydrazinecarboxamide) 103-03-7 1-Phenylsemicarbazide is an antifungal compound/agent.
1-Undecanoylglycerol V84008 1-Undecanoylglycerol 64633-19-8
16,17-Dihydroheronamide C V54011 16,17-Dihydroheronamide C 2698333-36-5 16,17-Dihydroheronamide C has antifungal activity and was designed as a probe for analysis of the mode of action of heronamide C.
2,2-Dibromopropanoic acid V53975 2,2-Dibromopropanoic acid 594-48-9 2,2-Dibromopropanoic acid is a dibromoproduct based on propanoic acid.
2,4′-Dichloroacetanilide (2,4′-二氯乙酰苯胺) V53906 2,4′-Dichloroacetanilide 3289-75-6 2,4′-Dichloroacetanilide is a fungus inhibitor.
2,6-Dihydroxy-4-methoxyacetophenone V52519 2,6-Dihydroxy-4-methoxyacetophenone 7507-89-3 2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin that can be extracted from the root tissue of Sanguisorba minor.
2-Dodecanol (2-十二醇 标准品) V54019 2-Dodecanol (2-Dodecanol standard) 10203-28-8 2-Dodecanol inhibits hyphal formation and SIR2 expression in C. albicans.
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