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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine V77436 (R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine (R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine is an analogue of purine nucleoside.
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl) benzoyl-L-ribofuranose V80063 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl) benzoyl-L-ribofuranose 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl) benzoyl-L-ribofuranose is an analogue of purine nucleoside.
1-(bD-Xylofuranosyl)-5-fluorouracil V77437 1-(bD-Xylofuranosyl)-5-fluorouracil 1-(bD-Xylofuranosyl)-5-fluorouracil is an analogue of purine nucleoside.
1-(bD-Xylofuranosyl)-5-methoxyuracil V77494 1-(bD-Xylofuranosyl)-5-methoxyuracil 1-(bD-Xylofuranosyl)-5-methoxyuracil is an analogue of purine nucleoside.
1-(bD-Xylofuranosyl)-5-trifluoromethyluracil V77495 1-(bD-Xylofuranosyl)-5-trifluoromethyluracil 1-(bD-Xylofuranosyl)-5-trifluoromethyluracil is an analogue of purine nucleoside.
1-(bD-Xylofuranosyl)-N6-(p-methoxybenzyl) adenine V80122 1-(bD-Xylofuranosyl)-N6-(p-methoxybenzyl) adenine 1-(bD-Xylofuranosyl)-N6-(p-methoxybenzyl) adenine is an analogue of purine nucleoside.
1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine V80123 1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine 1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenine nucleoside analogue.
1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine V77496 1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine 1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenine nucleoside analogue.
1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine V80343 1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine 1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenine nucleoside analog.
1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil V77504 1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil 1-[6-(Diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hexofuranosyl]uracil is a uridine nucleoside analogue.
2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine V77542 2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine 2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine is an analogue of purine nucleoside.
2'-beta-C-Ethynyl-5-methyluridine V80628 2'-beta-C-Ethynyl-5-methyluridine 2'-beta-C-Ethynyl-5-methyluridine is an analogue of purine nucleoside.
2'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine V77543 2'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine 2'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine V77544 2'-Deoxy-2'-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine 2'-Deoxy-2'-fluoro- N3-(2S)-(2-amino-3-carbonyl)-propyluridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-4'-thio-aD-arabinouridine V77545 2'-Deoxy-2'-fluoro-4'-thio-aD-arabinouridine 2'-Deoxy-2'-fluoro-4'-thio-aD-arabinouridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-ara-uridine V81072 2'-Deoxy-2'-fluoro-ara-uridine 2'-Deoxy-2'-fluoro-ara-uridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N1-methyladensoine V80752 2'-Deoxy-2'-fluoro-N1-methyladensoine 2'-Deoxy-2'-fluoro-N1-methyladensoine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N1-methyluridine V81073 2'-Deoxy-2'-fluoro-N1-methyluridine 2'-Deoxy-2'-fluoro-N1-methyluridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine V79988 2'-Deoxy-2'-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine 2'-Deoxy-2'-fluoro-N3-(2S)-[2-(tert-butoxy-carbonyl)-amino-3-carbonyl]propyluridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-(3-aminopropyl)uridine V80262 2'-Deoxy-2'-fluoro-N3-(3-aminopropyl)uridine 2'-Deoxy-2'-fluoro-N3-(3-aminopropyl)uridine is an analogue of purine nucleoside.
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