AMPK

AMPK

AMPK (AMP-activated protein kinase) is an enzyme that plays a role in cellular energy homeostasis.It is made up of three proteins (subunits), which when combined form a useful enzyme. The overall result of AMPK activation is stimulation of skeletal muscle fatty acid oxidation and muscle glucose uptake by pancreatic beta-cells. This is offset by inhibition of cholesterol, lipogenesis, and triglyceride synthesis, inhibition of adipocyte lipolysis, and stimulation of hepatic fatty acid oxidation and ketogenesis. As a metabolic master switch, AMPK controls a number of intracellular processes, such as the uptake of glucose by cells, the -oxidation of fatty acids, and the GLUT4 and mitochondrial biogenesis.

AMPK related products

Structure Cat No. Product Name CAS No. Product Description
V9698 6-Gingerol 23513-14-6 6-Gingerol is a novel and potent active constituent of fresh ginger.
V0244 A-769662 844499-71-4 A-769662 (A769662;A 769662), a thienopyridone analog, is a potent, alloesteric and reversible activator of AMPK (AMP-activated protein kinase)with antidiabetic activity.
V0245 Acadesine (AICAR; NSC-105823) 2627-69-2 Acadesine (also known as NSC105823,AICA-riboside, and AICAR) is a novel and potent AMPK (AMP-activated protein kinase) activatorwith potential antitumor and antidiabetic activity.
V51085 Aldometanib (LXY-05-029) aldolase inhibitor
V52430 Aldometanib (LXY-05-029) 2904601-67-6
V77269 AMARA peptide TFA
V55721 AMPK activator 10 1914176-03-6
V52421 AMPK activator 11 2948304-00-3
V55742 AMPK activator 12 431920-24-0
V77939 AMPK activator 13
V77267 AMPK activator 2 hydrochloride
V52420 AMPKactivator 4 2493239-46-4
V55743 AMPKactivator 9 1858204-23-5
V52419 AMPK-IN-1 1219739-95-3
V70222 AMPK-α1β1γ1 activator 1 1943510-86-8
V2166 ASP4132 tosylate 1640294-30-9 ASP4132 tosylate (ASP-4132) is an oral bioavailable AMPK activator (EC50 = 18 nM) with potential anticancer activity.
V2440 BC1618 2222094-18-8 BC-1618 is a potent and orally active Fbxo48 inhibitor.
V6440 Bempedoic acid (ESP55016; ETC1002) 738606-46-7 Bempedoic acid (formerly ESP-55016; ETC-1002; ESP55016; ETC1002;Nexletol;Bempedoate) is an ATP-citrate lyase (ACL) inhibitor as well as an activator of hepatic AMP-activated protein kinase (AMPK).
V52531 Bempedoic acid-d4 (ETC-1002-d4; ESP-55016-d4) 2408131-70-2
V56183 Bempedoic acid-d5 (ETC-1002-d5; ESP-55016-d5) 2408131-71-3
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