The cell-surface serine protease known as fibroblast activation protein (FAP) affects different hormones and elements of the extracellular matrix. FAP is frequently used as a marker for pro-tumorigenic stroma and is highly upregulated in a variety of cancers.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V125308 | 3BP-3580 | 2374782-82-6 | 3BP-3580 is a fibroblast activating protein (FAP) inhibitor (pIC50: 8.6) that can be used in cancer research. |
|
V86175 | 3BP-3940 | 2803421-14-7 | |
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V125309 | 3BP-4089 | 2581199-35-9 | 3BP-4089 is a highly effective fibroblast activating protein (FAP) targeting peptide. |
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V125310 | 3BP-4089 TFA | 3BP-4089 TFA is a highly effective fibroblast activation protein (FAP) targeting peptide. | |
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V86846 | [99mTc]Tc-6–1 | [99m Tc]Tc-6-1 is a 99mTc-labeled FAPI-46 derivative and a specific fibroblast activation protein (FAP) targeted radiotracer. | |
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V85878 | AlF-PD-FAPI | ||
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V129722 | AZD2389 | 2791472-12-1 | AZD2389 is a potent and orally effective FAP inhibitor. |
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V131858 | CL 118326 | 97012-61-8 | CL 118326 is a potent, selective competitive inhibitor of mammalian pancreatic phospholipase A2 (PLA2) and a weak antagonist of platelet-activating factor receptor (PAF receptor). |
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V133086 | Cys-FAP targeting peptide for FXX489 | Cys-FAP targeting peptide for FXX489 is the unlabeled peptide portion of FXX489. | |
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V133087 | Cys-FAP targeting peptide for FXX489 TFA | Cys-FAP targeting peptide for FXX489 TFA is the unlabeled peptide moiety of FXX489. | |
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V118440 | DOTA-2P (FAPI)2 | DOTA-2P(FAPI)2 is a dimeric FAP (fibroblast activating protein) targeting radioactive probe that can be used as a tracer for PET imaging and tumor targeting. | |
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V119240 | DOTA-ALB-01 | DOTA-ALB-01 is an albumin-bound FAP inhibitor (FAPI) ligand. | |
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V119214 | DOTA-ALB-02 | DOTA-ALB-02 is an albumin-bound FAP inhibitor (FAPI) ligand. | |
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V134275 | DOTA-C1-FAP-2286 | 3107530-08-2 | DOTA-C1-FAP-2286 is a cysteine-modified fibroblast activating protein (FAP) targeting radioligand. |
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V134281 | DOTA-NI-FAPI-04 | 3078291-78-5 | DOTA-NI-FAPI-04 is an FAP inhibitor (IC50 = 7.44 nM). |
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V93849 | DOTAGA.(SA.FAPi)2 analogue TFA | DOTAGA.(SA.FAPi)2 analog TFA is an analog of DOTAGA.(SA.FAPi)2 TFA, wherein the ligand and chelator moieties are the same as DOTAGA.(SA.FAPi)2 TFA. | |
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V94503 | DOTAGA.(SA.FAPi)2 TFA | DOTAGA.(SA.FAPi)2 TFA is a potent inhibitor of dimeric fibroblast activation protein (FAPi). | |
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V134277 | DOTAGA.Glu.(FAPi)2 | 2882922-68-9 | DOTAGA.Glu.(FAPi)2 is a FAPI homodimer in which a glutamic acid (Glu) linker connects FAPI and a chelating agent. |
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V135755 | FAP Ligand 2 | FAP Ligand 2 is a derivative of FAPI-46 and a tracer that specifically targets fibroblast activation protein (FAP). | |
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V135756 | FAP Ligand 3 | FAP Ligand 3 is a reagent that can bind to FAP, with a Ki value of 0.092 nM for human targets. |