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FAP

FAP

The cell-surface serine protease known as fibroblast activation protein (FAP) affects different hormones and elements of the extracellular matrix. FAP is frequently used as a marker for pro-tumorigenic stroma and is highly upregulated in a variety of cancers.

FAP related products

Structure Cat No. Product Name CAS No. Product Description
3BP-3940 V86175 3BP-3940 2803421-14-7
[99mTc]Tc-6–1 V86846 [99mTc]Tc-6–1 [99m Tc]Tc-6-1 is a 99mTc-labeled FAPI-46 derivative and a specific fibroblast activation protein (FAP) targeted radiotracer.
AlF-PD-FAPI V85878 AlF-PD-FAPI
DOTAGA.(SA.FAPi)2 analogue TFA V93849 DOTAGA.(SA.FAPi)2 analogue TFA DOTAGA.(SA.FAPi)2 analog TFA is an analog of DOTAGA.(SA.FAPi)2 TFA, wherein the ligand and chelator moieties are the same as DOTAGA.(SA.FAPi)2 TFA.
DOTAGA.(SA.FAPi)2 TFA V94503 DOTAGA.(SA.FAPi)2 TFA DOTAGA.(SA.FAPi)2 TFA is a potent inhibitor of dimeric fibroblast activation protein (FAPi).
FAP-IN-1 V79388 FAP-IN-1 2956858-96-9 FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor (antagonist) with IC50 of 3.3 nM.
FAP-IN-2 V74897 FAP-IN-2 2471983-20-5 FAP-IN-2 is an analogue of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor that can be used for tumor imaging.
FAP-IN-2 TFA V77022 FAP-IN-2 TFA FAP-IN-2 TFA is an analogue of 99mTc-labeled isonitrile-containing FAP inhibitor that can be used for tumor imaging.
FAP-IN-4 V86845 FAP-IN-4 FAP-IN-4 (Comp 10) is a fibroblast activation protein (FAP) inhibitor and a 18F-labeled PET tracer targeting FAP.
FAPI-2 V74893 FAPI-2 2370952-98-8 FAPI-2 is a fibroblast activation protein (FAP) inhibitor that has applications in cancer-related research.
FAPI-2 TFA V77023 FAPI-2 TFA FAPI-2 TFA is a fibroblast activation protein (FAP) inhibitor (antagonist) with potential use in cancer-related research.
FAPI-34 V74894 FAPI-34 2374782-07-5 FAPI-34 is a fibroblast activating protein (FAP) inhibitor (antagonist) with good pharmacokinetic and biochemical properties, disclosed in patent WO2019154886A1.
FAPI-46 V51734 FAPI-46 2374782-04-2 FAPI-46 is a quinoline-based activator of fibroblast-activated protein (FAP).
FAPI-74 V74898 FAPI-74 2374782-76-8 FAPI-74 is a PET (positron emission tomography) tracer for fibroblast activating protein.
FAPI-mFS V94533 FAPI-mFS 3023869-94-2 FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor that enhances its uptake and retention time in cancer cells through its covalent binding properties to FAP.
Fluorogen binding modulator-1 V74895 Fluorogen binding modulator-1 510716-65-1 Fluorogen binding modulator-1 (PubChem SID 125240934) is a fluorescein-activated protein (FAP)-fluorogen binding modulator with a -log EC50 of 6.61 for AM2.2-β2AR and AM2.2-gpr32 respectively.
FT-FAPI-12_9 V100354 FT-FAPI-12_9 2883407-81-4 FT-FAPI-12_9 is a FAP conjugate that can be used to synthesize the FAP-targeted radiotracer FAPI-46.
FT-FAPI-12_9 TFA V97374 FT-FAPI-12_9 TFA FT-FAPI-12_9 (TFA) is a FAP conjugate that can be used to synthesize the FAP-targeted radiotracer FAPI-46.
NH2-UAMC1110 TFA V76701 NH2-UAMC1110 TFA 2990021-73-1 NH2-UAMC1110 TFA is a UAMC1110 analogue that may be utilized in the synthesis/preparation of FAPI-QS.
PNT6555 V85436 PNT6555
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