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FAP

FAP

The cell-surface serine protease known as fibroblast activation protein (FAP) affects different hormones and elements of the extracellular matrix. FAP is frequently used as a marker for pro-tumorigenic stroma and is highly upregulated in a variety of cancers.

FAP related products

Structure Cat No. Product Name CAS No. Product Description
3BP-3940 V86175 3BP-3940 2803421-14-7
AlF-PD-FAPI V85878 AlF-PD-FAPI
FAP-IN-1 V79388 FAP-IN-1 FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor (antagonist) with IC50 of 3.3 nM.
FAP-IN-2 V74897 FAP-IN-2 2471983-20-5 FAP-IN-2 is an analogue of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor that can be used for tumor imaging.
FAP-IN-2 TFA V77022 FAP-IN-2 TFA FAP-IN-2 TFA is an analogue of 99mTc-labeled isonitrile-containing FAP inhibitor that can be used for tumor imaging.
FAPI-2 V74893 FAPI-2 2370952-98-8 FAPI-2 is a fibroblast activation protein (FAP) inhibitor that has applications in cancer-related research.
FAPI-2 TFA V77023 FAPI-2 TFA FAPI-2 TFA is a fibroblast activation protein (FAP) inhibitor (antagonist) with potential use in cancer-related research.
FAPI-34 V74894 FAPI-34 2374782-07-5 FAPI-34 is a fibroblast activating protein (FAP) inhibitor (antagonist) with good pharmacokinetic and biochemical properties, disclosed in patent WO2019154886A1.
FAPI-46 V51734 FAPI-46 2374782-04-2 FAPI-46 is a quinoline-based activator of fibroblast-activated protein (FAP).
FAPI-74 V74898 FAPI-74 2374782-76-8 FAPI-74 is a PET (positron emission tomography) tracer for fibroblast activating protein.
Fluorogen binding modulator-1 V74895 Fluorogen binding modulator-1 510716-65-1 Fluorogen binding modulator-1 (PubChem SID 125240934) is a fluorescein-activated protein (FAP)-fluorogen binding modulator with a -log EC50 of 6.61 for AM2.2-β2AR and AM2.2-gpr32 respectively.
NH2-UAMC1110 TFA V76701 NH2-UAMC1110 TFA NH2-UAMC1110 TFA is a UAMC1110 analogue that may be utilized in the synthesis/preparation of FAPI-QS.
PNT6555 V85436 PNT6555
SB03178 V83509 SB03178 2952588-12-2
Sibrotuzumab (BIBH 1; Anti-Human FAP Recombinant Antibody) V74891 Sibrotuzumab (BIBH 1; Anti-Human FAP Recombinant Antibody) 216669-97-5 Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody (mAb) targeting fibroblast activating protein (FAP).
Zilganersen (ION373) V74896 Zilganersen (ION373) 2305355-56-8 Zilganersen (ION373) is an inhibitor (blocker/antagonist) of glial fibrillary acidic protein (GFAP) and is an antisense oligonucleotide.
Zilganersen sodium (ION373 sodium) V74892 Zilganersen sodium (ION373 sodium) 2305355-64-8 Zilganersen sodium is an inhibitor (blocker/antagonist) of glial fibrillary acidic protein (GFAP) and may be utilized in the study of Alexander disease (AxD).
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