| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V1369 | DMH1 | 1206711-16-1 | DMH1 (DMH-1; DMH 1) is a selective and 2nd-generation small molecule inhibitor of BMP (bone morphogenetic protein) receptor inhibitor with potential antitumor activity. |
|
V1360 | Galunisertib (LY2157299) | 700874-72-2 | Galunisertib (formerly known as LY2157299; LY-2157299) is a selective, ATP-mimetic, and orally bioavailable small molecule inhibitor of the TGFβ receptor I (TβRI) with potential anticancer activity. |
|
V1376 | GW788388 | 452342-67-5 | GW788388 (GW-788388; GW 788388) is an inhibitor of ALK5/TGF-β type II receptor with potential antifibrotic activity. |
|
V1375 | Hesperetin | 520-33-2 | Hesperetin (YSO-2; YSO 2;Hesperitin; Hesperin; Prestwick_908) is a naturally occuring flavonoid with a vareity of biological properties such as antioxidant,neuroprotective and anti-inflammatory activity. |
|
V1374 | K02288 | 1431985-92-0 | K02288 (K-02288; K 02288) is a potent,2-aminopyridine-based and selective small molecule inhibitor of the BMP (bone morphogenetic protein) signaling pathway with the potential to treat the progressively debilitating musculoskeletal disease fibrodysplasia ossificans progressiva (FOP). |
|
V1368 | Kartogenin (KGN) | 4727-31-5 | Kartogenin (abbreviated as KGN) is a small heterocyclic compound acting as an activator/inducer of the smad4/smad5 pathway. |
|
V1359 | LDN-193189 (DM-3189) | 1062368-24-4 | LDN-193189 (also called LDN193189;DM-3189;DM3189) is a highly potent andselective small molecule inhibitor of the BMP (bone morphogenetic protein) signaling pathway with potential antineoplastic activity. |
|
V1372 | LDN-193189 4HCl | 1062368-62-0 | LDN193189 4HCl (LDN-193189;DM-3189;LDN 193189;DM 3189), the tetrahydrochloride salt ofLDN193189, is a highly potent andselective inhibitor of the BMP (bone morphogenetic protein) signaling pathway with potential anticancer activity. |
|
V1370 | LDN-212854 | 1432597-26-6 | LDN-212854 (LDN 212854; LDN212854) is a potent and selective inhibitor of BMP (bone morphogenetic protein) receptor with potential antineoplastic activity. |
|
V1365 | LDN-214117 | 1627503-67-6 | LDN-214117 (LDN 214117; LDN214117) is a novel, potent and selective ALK2 (BMP type I receptor kinase) inhibitor with potential anticancer activity. |
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V1361 | LY2109761 | 700874-71-1 | LY2109761 (LY-2109761; LY 2109761) is a novel, orally bioavailable and selective dual inhibitor of transforming growth factor beta receptor I/II (TGF-β receptor type I/II: TβRI/II) with potential antitumor activity. |
|
V1377 | LY364947 (HTS466284) | 396129-53-6 | LY364947 (also known as HTS-466284;LY 364947;HTS466284;LY-364947) is a potent, selective and ATP-competitive inhibitor of TGFβR-I with potential antineoplastic activity. |
|
V1371 | ML347 | 1062368-49-3 | ML347 (formerly known as ML-347; LDN193719; ML 347; LDN-193719) is a novel, highly potent and selective inhibitor of BMP (bone morphogenetic protein) receptor with potential anticancer activity. |
|
V1367 | OICR-0547 | 1801873-49-3 | OICR-0547 (OICR 0547;OICR0547), an OICR-9429 analog, is an antagonist of the protein protein interaction between WDR5 and the peptide regions of MLL and Histone 3 with potential antineoplastic activity. |
|
V1364 | Pirfenidone (AMR69) | 53179-13-8 | Pirfenidone (formerly AMR69;S7701, AMR-69; S-7701; trade name: Pirespa; Pirfenex; Deskar, Esbriet) is a potentinhibitor for TGF-β production and TGF-β stimulated collagen production with anti-fibrotic and anti-inflammatory properties. |
|
V1373 | RepSox (SJN 2511) | 446859-33-2 | RepSox (also called E-616452, SJN-2511; E 616452; SJN 2511, and ALK5 Inhibitor II) is a potent, cell permeable, and selective inhibitor of the TGFβR-1/ALK5 (transforming growth factor-beta type I receptor, ALK5) with important biological activity. |
|
V1358 | SB431542 | 301836-41-9 | SB431542 (SB-431542; SB 431542) is a novel and selective inhibitor of ALK5/TGF-β type I Receptor with potential antitumor activity. |
|
V1363 | SB505124 | 694433-59-5 | SB505124 (SB-505124; SB 505124) is a novel, potent and selective inhibitor of TGFβR (TGF-β Receptor type I receptor) for ALK4, ALK5 (activin receptor-like kinase) with potential antineoplastic activity. |
|
V1362 | SB525334 | 356559-20-1 | SB525334 (SB-525334; SB 525334) is a potent and selective inhibitor of TGF-β (transforming growth factor-β) receptor I, ALK5 (activin receptor-like kinase) with potential anti-fibrotic activity. |
|
V1366 | SD-208 | 627536-09-8 | SD-208 (SD208; SD 208;TGF-β RI Kinase Inhibitor V) is an orally bioavailable and selective TGF-βRI (ALK5) inhibitor with potential antitumor activity. |
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