|
V77719
|
AB-680 ammonium |
|
AB-680 ammonium is a potent, reversible, and selective CD73 (ectonucleotidase) inhibitor (antagonist) with a Ki of 4.9 pM for hCD73 and selectivity for the related extracellular nucleotidase CD39. |
|
V51270
|
BK-50164 |
2204291-78-9 |
BK50164 is a potent CD73 with IC50 of 13.089 µM. |
|
V74772
|
CD73-IN-12 |
2773502-79-5 |
CD73-IN-12 is a potent inhibitor of CD73, which is linked to tumor growth, angiogenesis, and metastasis. |
|
V74771
|
CD73-IN-13 |
2773423-69-9 |
CD73-IN-13 is a potent inhibitor of CD73, which is linked to tumor growth, angiogenesis, and metastasis. |
|
V51264
|
CD73-IN-14 |
2407356-67-4 |
CD73-IN-14 is a specific, and orally bioactive CD73-fold with IC50 of 0.17 nM. |
|
V74773
|
CD73-IN-2 |
2452209-05-9 |
CD73-IN-2 is a potent CD73 inhibitor (antagonist) with IC50 of 0.09 nM. |
|
V51265
|
CD73-IN-4 |
2216764-29-1 |
CD73-IN-4 is a selective, highly effective methylene phosphate CD73 with IC50 of 2.6 nM for human CD73. |
|
V51266
|
CD73-IN-5 |
2412019-99-7 |
CD73-IN-5 is a potent and specific non-nucleotide small molecule CD73 inhibitor (IC50 = 19 nM). |
|
V74770
|
Dresbuxelimab (AK-119) |
2550560-20-6 |
Dresbuxelimab (AK-119) is an IgG-κ monoclonal antibody (mAb) targeting CD73. |
|
V76773
|
MethADP triammonium (Adenosine 5'-(α,β-methylene)diphosphate triammonium) |
|
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. |
|
V51267
|
Mupadolimab (CPI-006) |
2451856-97-4 |
Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 mAb that activates/agonizes CD73POS B cells. |
|
V76679
|
OP-5244 sodium |
|
OP-5244 sodium is a potent and orally bioactive CD73 inhibitor (antagonist) with IC50 of 0.25 nM. |
|
V51268
|
Uliledlimab (TJ-004309) |
2378407-27-1 |
Uliledlimab is a potent anti-CD73 human monoclonal antibody (mAb). |