PAFR

PAFR

The platelet-activating factor receptor (PAFR) is a G-protein-coupled receptor involved in a wide variety of pathophysiological processes in addition to normal physiological ones. Platelet-activating factor (PAF), a phospholipid mediator of cell-to-cell communication with a variety of physiological effects, is what causes PAFR to react. Platelet-activating factor (PAF) binding stimulates the PAFR, which results in a variety of powerful biological activities and has a significant impact on anaphylaxis, endotoxic shock, allergic disorders, and acute inflammation. PAF, a strong and adaptable mediator of inflammation, is produced by a variety of cell types and tissues, but leukocytes in particular.

PAFR related products

Structure Cat No. Product Name CAS No. Product Description
V1493 Ginkgolide B (BN-52021) 15291-77-7 Ginkgolide B (Bilobalide B; BN-52051; BN52051) is a naturally occuring compound acting as a PAFR (platelet-activating factor receptor) antagonist with an IC50 of 3.6 μM.
V74452 Homoeriodictyol 7-O-β-D-glucoside 14982-11-7
V74453 Kadsurenin B 145701-13-9
V74451 Kadsurenolone 95851-37-9
V74450 Kadsurin A 99340-07-5
V1494 NVP-TNKS656 1419949-20-4 NVP-TNKS656 (also called TNKS-656; NVP-TNKS-656; TNKS 656; NVP-TNKS 656) is a selective, and orally bioactive tankyrase inhibitor with potential antitumor activity.
V74455 Pinusolidic acid 40433-82-7
V74456 Piperulin A 164268-04-6
V74454 Pregomisin 66280-26-0
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