The platelet-activating factor receptor (PAFR) is a G-protein-coupled receptor involved in a wide variety of pathophysiological processes in addition to normal physiological ones. Platelet-activating factor (PAF), a phospholipid mediator of cell-to-cell communication with a variety of physiological effects, is what causes PAFR to react. Platelet-activating factor (PAF) binding stimulates the PAFR, which results in a variety of powerful biological activities and has a significant impact on anaphylaxis, endotoxic shock, allergic disorders, and acute inflammation. PAF, a strong and adaptable mediator of inflammation, is produced by a variety of cell types and tissues, but leukocytes in particular.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V84253 | 2-O-Ethyl PAF C-16 | 78858-42-1 | |
|
V128403 | Aggreceride A | 19207-26-2 | Aggreceride A is a platelet aggregation inhibitor. |
|
V128404 | Aggreceride B | 104700-85-8 | Aggreceride B is a platelet aggregation inhibitor. |
|
V128405 | Aggreceride C | 104700-86-9 | Aggreceride C is a platelet aggregation inhibitor. |
|
V129216 | Apafant-d8 | 1185101-22-7 | Apafant-d8 is a deuterated Apafant. |
|
V114666 | BN-50726 | 127279-06-5 | BN-50726 is a potent platelet-activating factor (PAF) receptor antagonist. |
|
V84332 | Carbamyl-PAF (C-PAF) | 91575-58-5 | |
|
V131954 | Clotizolam | 54123-06-7 | Clotizolam is a thienobenzodiazepine derivative that antagonizes platelet-activating factor (PAF). |
|
V86649 | CP-96021 | 139401-43-7 | CP-96021 is a highly effective, orally available leukotriene D4 (LTD4 Ki=34 μM) / platelet activating factor (PAF Ki=37 μM) receptor antagonist. |
|
V136945 | GS-1160-180 | 111878-47-8 | GS-1160-180 is a PAF receptor antagonist. |
|
V84196 | Hexanolamino PAF C-16 (1-O-Hexa-decyl-2-acetyl-sn-glycero-3-phospho(N,N,N-trimethyl)-hexanolamine) | 137566-83-7 | |
|
V74452 | Homoeriodictyol 7-O-β-D-glucoside | 14982-11-7 | Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. |
|
V74453 | Kadsurenin B | 145701-13-9 | Kadsurenin B is a PAF (platelet-activating factor) antagonist (inhibitor) with neuro-protection activity. |
|
V74451 | Kadsurenolone | 95851-37-9 | Kadsurenone is a lignan with specific antagonistic activity of platelet-activating factor. |
|
V74450 | Kadsurin A | 99340-07-5 | Kadsurin A is a new lignan extracted from Piper futokadsura. |
|
V112194 | Minopafant | 128420-61-1 | Minopafen (E 5880) is a platelet-activating factor receptor antagonist. |
|
V114532 | MKC-963 | 149549-14-4 | MKC-963 is an orally effective and potent platelet aggregation inhibitor that targets platelet aggregation-related pathways. |
|
V1494 | NVP-TNKS656 | 1419949-20-4 | NVP-TNKS656 (also called TNKS-656; NVP-TNKS-656; TNKS 656; NVP-TNKS 656) is a selective, and orally bioactive tankyrase inhibitor with potential antitumor activity. |
|
V106033 | Oxopurpureine | 32845-27-5 | Oxypurpurin is an oxo-aporphyrin with antiplatelet aggregation activity. |
|
V84288 | PAF (C18) | 74389-69-8 |
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