The platelet-activating factor receptor (PAFR) is a G-protein-coupled receptor involved in a wide variety of pathophysiological processes in addition to normal physiological ones. Platelet-activating factor (PAF), a phospholipid mediator of cell-to-cell communication with a variety of physiological effects, is what causes PAFR to react. Platelet-activating factor (PAF) binding stimulates the PAFR, which results in a variety of powerful biological activities and has a significant impact on anaphylaxis, endotoxic shock, allergic disorders, and acute inflammation. PAF, a strong and adaptable mediator of inflammation, is produced by a variety of cell types and tissues, but leukocytes in particular.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V1493 | Ginkgolide B (BN-52021) | 15291-77-7 | Ginkgolide B (Bilobalide B; BN-52051; BN52051) is a naturally occuring compound acting as a PAFR (platelet-activating factor receptor) antagonist with an IC50 of 3.6 μM. |
|
V74452 | Homoeriodictyol 7-O-β-D-glucoside | 14982-11-7 | Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. |
|
V74453 | Kadsurenin B | 145701-13-9 | Kadsurenin B is a PAF (platelet-activating factor) antagonist (inhibitor) with neuro-protection activity. |
|
V74451 | Kadsurenolone | 95851-37-9 | Kadsurenone is a lignan with specific antagonistic activity of platelet-activating factor. |
|
V74450 | Kadsurin A | 99340-07-5 | Kadsurin A is a new lignan extracted from Piper futokadsura. |
|
V1494 | NVP-TNKS656 | 1419949-20-4 | NVP-TNKS656 (also called TNKS-656; NVP-TNKS-656; TNKS 656; NVP-TNKS 656) is a selective, and orally bioactive tankyrase inhibitor with potential antitumor activity. |
|
V74455 | Pinusolidic acid | 40433-82-7 | Pinusolidic Acid is a platelet activating factor (PAF) inhibitor (antagonist) with IC50 of 23 μM. |
|
V74456 | Piperulin A | 164268-04-6 | Piperulin A is a potent PAFR inhibitor. |
|
V74454 | Pregomisin | 66280-26-0 | Pregomisin is a natural compound extracted from the fruit of Schisandra chinensis. |
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