| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V3885 | (R,S)-Ivosidenib (AG-120) | 1448346-63-1 | (R,S)-Ivosidenib(AG120; RG120; AG-120; RG-120;Tibsovo), the racemic mixture ofIvosidenib, is an orally bioavailable andsmall moleculeIDH1 inhibitor that inhibits mutated cytosolic isocitrate dehydrogenase 1 (IDH1). |
|
V3151 | 3-Methylpyrazole | 1453-58-3 | 3-Methylpyrazole (also known as 3-MP) is a weak inhibitor ofalcohol dehydrogenase,which are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). |
|
V0855 | AGI-5198 | 1355326-35-0 | AGI-5198 (also know as IDH-C35; IDHC35; AGI-5198; AGI 5198) is a novel, highly potent and selective inhibitor of IDH1 (isocitrate dehydrogenase 1) R132H/R132C mutants with potential anticancer activity. |
|
V0862 | AGI-6780 | 1432660-47-3 | AGI-6780 (AGI6780; AGI 6780) is a potent and selective inhibitor oftumor-associated mutant IDH2 (isocitrate dehydrogenases 2) R140Q with potential anti-inflammatory activity. |
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V0865 | Ammonium Glycyrrhizinate | 1407-03-0 | Ammonium Glycyrrhizinate (AMGZ, Glycyram;Monoammonium glycyrrhizinate), a triterpenoid saponin analog, is responsible for thesweet-tasting of Glycyrrhiza glabra root. |
|
V11730 | ASP9521 | 1126084-37-4 | ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). |
|
V4174 | BAY-1436032 | 1803274-65-8 | BAY-1436032 is a novel and potent pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor both in vitro and in vivo. |
|
V5125 | Brequinar (DUP785; NSC 368390) | 96187-53-0 | Brequinar (formerly DUP-785; NSC-368390),a synthetic quinolinecarboxylic acid analog, is a novel and potent inhibitor ofdihydroorotate dehydrogenasewith potent activities against a broad spectrum of viruses andantineoplastic properties. |
|
V17016 | Brequinar Sodium (DUP-785; NSC368390) | 96201-88-6 | Brequinar sodium (also known as DUP785;NSC-368390),a synthetic quinolinecarboxylic acid analog, is a novel and potent inhibitor ofdihydroorotate dehydrogenasewith potent activities against a broad spectrum of viruses andantineoplastic properties. |
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V16006 | BVT-2733 | 376640-41-4 | BVT-2733 is a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, which attenuates obesity and inflammation in diet-induced obese mice. |
|
V18887 | CVT-10216 | 1005334-57-5 | CVT-10216, an isoflavone compound, is a novel, highly potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50s of 29 and 1300 nM for ALDH2 and ALDH1, respectively. |
|
V0853 | Devimistat (CPI-613) | 95809-78-2 | Devimistat (formerly also known as CPI613; CPI 613; CPI-613), a synthetic lipoate analog, is a novel and potent inhibitor ofpyruvate dehydrogenase (PDH)andα-ketoglutarate dehydrogenase with potential chemopreventive and antineoplastic activities. |
|
V39998 | DHODH-IN-11 | 1263303-95-2 | DHODH-IN-11 (Compound 14b) is a Leflunomide analogue and a weak inhibitor of dihydroorotate dehydrogenase (DHODH) with a pKa of 5.03. |
|
V0859 | Disulfiram | 97-77-8 | Disulfiram (Disulfan; NSC 190940;Dicupral; Disetil;NSC190940; Tetraethylthiuram disulfide; TETD)is a potent andspecific inhibitor of aldehyde-dehydrogenase (ALDH1) that is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. |
|
V2851 | Enasidenib (AG-221) | 1446502-11-9 | Enasidenib (formerly AG221; CC90007; AG-221; CC-90007; Idhifa) is an orally bioactive, first-in-class, and selective inhibitor of IDH2 (Isocitrate dehydrogenase 2) with potential anticancer activity. |
|
V0864 | Enoxolone | 471-53-4 | Enoxolone (Glycyrrhetin; NSC 35347;Enoxolone; Glycyrrhetic acid; BRN-2229654; NSC-35347) is a novel, potent,pentacyclic triterpenoid derivative of the beta-amyrin type with potential liver-protecting effects. |
|
V0866 | Gimeracil | 103766-25-2 | Gimeracil (chlorodihydroxypyridine; CDHP; Gimestat), a pyridine/pyridone analog and an approved anticancer drug, is a potent inhibitor of the dihydropyrimidine dehydrogenase (DPYD) enzyme with potential anti-neoplastic activity. |
|
V0870 | Glycyrrhizin (Glycyrrhizic Acid) | 1405-86-3 | Glycyrrhizic Acid (also known as Glizigen; Liquorice; Glycyrrhizin), a naturally occurring triterpenoid saponin analog found in the licorice root, is a widely used anti-inflammatory agent but also has anticancer activities. |
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V0871 | Gossypol Acetate | 12542-36-8 | Gossypol Acetate (Pogosin, AT101; BL-193; AT-101)is a naturally occuring polyphenolic aldehyde with potential anticancer activity. |
|
V0869 | Isovaleramide | 541-46-8 | Isovaleramide (NPS-1776; NPS 1776; NPS1776; 3-Methylbutanamide), a natural product found in Valeriana pavonii, is a potent anticonvulsant agent that acts as an inhibitor of alcohol dehydrogenases. |
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