Dehydrogenase

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Dehydrogenase

Dehydrogenase related products

Cat No.	Product Name	CAS No.	Product Description
V3885	Ivosidenib (AG-120) racemate	1448346-63-1	Ivosidenib racemate (AG120; RG120; AG-120; RG-120;Tibsovo), the racemic mixture ofIvosidenib, is an orally bioavailable andsmall moleculeIDH1 inhibitor that inhibits mutated cytosolic isocitrate dehydrogenase 1 (IDH1).
V0856	MK-8245	1030612-90-8	MK-8245 (MK8245; MK 8245) is a novel and potentliver-targeted inhibitor of stearoyl-CoA desaturase (SCD) with anti-diabetic and anti-dyslipidemic activities.
V3151	3-Methylpyrazole	1453-58-3	3-Methylpyrazole (also known as 3-MP) is a weak inhibitor ofalcohol dehydrogenase,which are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH).
V0855	AGI-5198	1355326-35-0	AGI-5198 (also know as IDH-C35; IDHC35; AGI-5198; AGI 5198) is a novel, highly potent and selective inhibitor of IDH1 (isocitrate dehydrogenase 1) R132H/R132C mutants with potential anticancer activity.
V0862	AGI-6780	1432660-47-3	AGI-6780 (AGI6780; AGI 6780) is a potent and selective inhibitor oftumor-associated mutant IDH2 (isocitrate dehydrogenases 2) R140Q with potential anti-inflammatory activity.
V11730	ASP9521	1126084-37-4	ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).
V4174	BAY-1436032	1803274-65-8	BAY-1436032 is a novel and potent pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor both in vitro and in vivo.
V16006	BVT-2733	376640-41-4	BVT-2733 is a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, which attenuates obesity and inflammation in diet-induced obese mice.
V18887	CVT-10216	1005334-57-5	CVT-10216, an isoflavone compound, is a novel, highly potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50s of 29 and 1300 nM for ALDH2 and ALDH1, respectively.
V39998	DHODH-IN-11	1263303-95-2	DHODH-IN-11 (Compound 14b) is a Leflunomide analogue and a weak inhibitor of dihydroorotate dehydrogenase (DHODH) with a pKa of 5.03.
V0858	NCT-501	1802088-50-1	NCT-501 (NCT501; NCT 501), a theophylline-based compound, is a novel, highly potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with potential anticancer activity.
V26321	NCT-503	1916571-90-8	NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 of 2.5 µM.
V4546	R-GNE-140	2003234-63-5	(R)-GNE-140, the S-enantiomer ofGNE-140, is a novel and potent lactate dehydrogenase (LDHA) inhibitor with potential anticancer activity.
V100440	Succinate dehydrogenase-IN-2	3023681-83-3	Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor of succinate dehydrogenase (SDH) with IC50 of 1.22 mg/L.
V104901	Succinate dehydrogenase-IN-4
V104906	Succinate dehydrogenase-IN-5
V0857	SW-033291	459147-39-8	SW033291 (SW-033291; SW 033291) is a selective and high affinity inhibitor of the prostaglandin-degrading enzyme 15-PGD (15-hydroxyprostaglandin dehydrogenase) with potential kidney and liver protective effects.
V2766	Vorasidenib	1644545-52-7	Vorasidenib (formerly known as AG-881; AG881) is a selective and orally bioavailable inhibitor of mutated forms of both isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) with potential anticancer activity.
V0859	Disulfiram	97-77-8	Disulfiram (Disulfan; NSC 190940;Dicupral; Disetil;NSC190940; Tetraethylthiuram disulfide; TETD)is a potent andspecific inhibitor of aldehyde-dehydrogenase (ALDH1) that is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
V0866	Gimeracil	103766-25-2	Gimeracil (chlorodihydroxypyridine; CDHP; Gimestat), a pyridine/pyridone analog and an approved anticancer drug, is a potent inhibitor of the dihydropyrimidine dehydrogenase (DPYD) enzyme with potential anti-neoplastic activity.