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Influenza Virus

Influenza Virus

The influenza virus is a member of the Orthomyxoviridae family of segmented, single-stranded, negatively charged RNA viruses. Three different influenza virus types—A, B, and C—are included in this group. While type B and C viruses only affect humans, type A viruses affect both domesticated and wild birds, horses, swine, other mammals, and humans.In the United States, seasonal epidemics of disease are brought on by human influenza A and B viruses almost every winter. An influenza pandemic can be brought on by the spread of a brand-new, radically different influenza virus. Infections with influenza type C are thought to only cause a mild respiratory illness and not epidemics. Each virus subtype has undergone mutation, resulting in a variety of strains with various levels of pathogenicity; some are pathogenic to one species but not to others, and some are pathogenic to several.

Influenza Virus related products

Structure Cat No. Product Name CAS No. Product Description
Anti-Influenza agent 6 V101734 Anti-Influenza agent 6 2917502-08-8 Anti-influenza agent 6 (compound 19b) exhibited inhibitory activity against A/WSN/33/H1N1 (EC50 = 0.015 μM) and influenza B viruses Yamagata/16/88 (EC50 = 0.073 μM) and Victotis/2/87 (EC50 = 0.067 μM).
ATV03 V94408 ATV03 ATV03 is an anti-influenza virus drug with excellent activity against influenza A and B viruses.
AV-5080 V93070 AV-5080 1448435-38-8 AV-5080 is an oral neuraminidase inhibitor for use in influenza A and B virus research.
Bonaphthone V88289 Bonaphthone 6954-48-9 Bonaphthone is an antiviral agent with activity against DNA and RNA viruses.
Cap-dependent endonuclease-IN-28 V102232 Cap-dependent endonuclease-IN-28 Cap-dependent endonuclease-IN-28 (compound 11) is a potent cap-dependent endonuclease (CEN) inhibitor.
Chelidonine hydrochloride V89524 Chelidonine hydrochloride 4312-31-6 Chelidonine (hydrochloride) is the hydrochloride form of Chelidonine.
F0045(S) V101560 F0045(S) 2716077-17-5 F0045(S) is a potent influenza hemagglutinin inhibitor with a KD of 6.1 µM.
IAV-IN-3 V89688 IAV-IN-3 IAV-IN-3 (Compound (R,S)-16s) is an anti-influenza A virus (IAV) compound (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM against MDCK cells).
Influenza A virus-IN-14 V101860 Influenza A virus-IN-14 Influenza A virus-IN-14 (Compound 37) is an inhibitor of influenza A virus (IAV) and can inhibit H1N1 with EC50 of 23 nM.
KIN1148 V3003 KIN1148 1428729-56-9 KIN1148 isa small-molecule agonist of the IRF3 (RIG-I-like receptor) pathway and a novel adjuvant therapy of influenza vaccine that is able to enhance the efficacy of flu vaccine.
Methyl isoferulate V96960 Methyl isoferulate 16980-82-8 Methyl isoferulate (methyl isoferulate) is an anti-H1N1 swine flu compound.
MI-1904 V100322 MI-1904 3033379-90-4 MI-1904 is an inhibitor of matriptase/TMPRSS2 with antiviral activity against influenza viruses H1N1 and H9N2.
Neuraminidase-IN-17 V88291 Neuraminidase-IN-17 2935407-34-2 Neuraminidase-IN-17 (compound N10) is a neuraminidase inhibitor with EC50 of 0.11 μM.
Neuraminidase-IN-18 V89670 Neuraminidase-IN-18 2935407-32-0 Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor.
Neuraminidase-IN-21 V99708 Neuraminidase-IN-21 Neuraminidase-IN-21 (Compound 6d) is an influenza H1N1 virus neuraminidase inhibitor with IC50 of 0.30 µM for neuraminidase and 30.01 µM for influenza H1N1 virus strains.
Neuraminidase-IN-22 V97261 Neuraminidase-IN-22 Neuraminidase-IN-22 (compound 3e) is a potent, selective and orally active neuraminidase inhibitor with IC50 of 0.03 µM.
OSC-GCDI(P) V101352 OSC-GCDI(P) OSC-GCDI(P) is an oral broad-spectrum anti-influenza virus drug that has significant inhibitory effects on both wild-type and oseltamivir-resistant strains (H275Y) in a mouse infection model.
PAN endonuclease-IN-2 V88290 PAN endonuclease-IN-2 PAN endonuclease-IN-2 (compound T-31) is a PAN endonuclease inhibitor (IC50: 0.15 μM) and antiviral agent with broad-spectrum anti-influenza activity.
Pimodivir hydrochlorid hemihydrate V95267 Pimodivir hydrochlorid hemihydrate 1777721-70-6 Pimodivir hydrochloride hemihydrate (VX-787) is an oral influenza A virus polymerase inhibitor that works by inhibiting the PB2 subunit.
RdRP-IN-8 V99114 RdRP-IN-8 RdRP-IN-8 (Compound 45) is an anti-influenza virus compound.
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