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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
(6Z,16Z)-12-((Z)-Dec-4-enyl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate V60066 (6Z,16Z)-12-((Z)-Dec-4-enyl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate 1450888-71-7 Genevant CL1 is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
(R)-Chol-TPP V77379 (R)-Chol-TPP (R)-Chol-TPP is a mitochondria-targeted liposomal ligand for pH-redox reactions.
(Z)-KC02 V73412 (Z)-KC02 1646795-60-9 (Z)-KC02 is an inhibitor (blocker/antagonist) of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS.
1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine V90381 1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine 36314-47-3 1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions and is commonly used to prepare liposomes and artificial membranes to study membrane dynamics.
1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) V84244 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) 5634-86-6
1,2-Diarachidoyl-sn-glycero-3-phosphocholine V90376 1,2-Diarachidoyl-sn-glycero-3-phosphocholine 61596-53-0 1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid with saturated long-chain (20:0) arachidonic acid inserted at the sn-1 and sn-2 positions.
1,2-Dibehenoyl-sn-glycero-3-phosphocholine V87538 1,2-Dibehenoyl-sn-glycero-3-phosphocholine 17688-29-8 1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC) is a phospholipid found in cell membranes.
1,2-Didecanoyl PC V90347 1,2-Didecanoyl PC 3436-44-0 1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine that can be introduced into single-chain mean field theory as a coarse-grained model of saturated phospholipids.
1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine V90352 1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine 253685-27-7 1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that shows very promising P-gp inhibitory effects at 0.3 mM concentration.
1,2-Dilauroyl-sn-glycero-3-phosphate sodium V90380 1,2-Dilauroyl-sn-glycero-3-phosphate sodium 108321-06-8 1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid with medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions and can be used for the preparation of liposomes.
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) V83376 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) 59752-57-7
1,2-Dilinoleoyl-sn-glycero-3-PC V90344 1,2-Dilinoleoyl-sn-glycero-3-PC 6542-05-8 1,2-Dilinoleoyl-sn-glycero-3-PC (Dilinoleoyllecithin) is a phospholipid.
1,2-DImyristoyl-rac-glycero-3-phosphocholine V73459 1,2-DImyristoyl-rac-glycero-3-phosphocholine 18656-38-7 1,2-DImyristoyl-rac-glycero-3-phosphocholine (DMPC) is a zwitterionic phospholipid chosen for simple eukaryotic cell membranes, mimicking the neutral charge of the eukaryotic plasma membrane surface.
1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium V90377 1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium 80724-31-8 1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions and can be used for the preparation of liposomes.
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium V90385 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium 105405-50-3 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with a myristic acid tail (14:0) and contains a carboxylic acid (COOH) and an amine (NH2) in its head group, which can be used in the preparation of liposomes.
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC; Dimyristoyl phosphatidylcholine) V74061 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC; Dimyristoyl phosphatidylcholine) 18194-24-6 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes and lipid bilayers.
1,2-Dioctanoyl-sn-glycero-3-phosphocholine V73466 1,2-Dioctanoyl-sn-glycero-3-phosphocholine 19191-91-4 1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid extensively used as a component of liposome formulations and drug delivery systems.
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) V74058 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) 90693-88-2 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium is a phosphoserine/phosphatidylserine alternative.
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine V89604 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine 3922-61-0 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used to prepare liposomes and monolayers for the study of membrane permeability and monolayer viscosity, respectively.
1,2-Distaroyl-sn-glycero-3-phosphate sodium (distearoylphosphatidic acid) V73451 1,2-Distaroyl-sn-glycero-3-phosphate sodium (distearoylphosphatidic acid) 108321-18-2 1,2-Distaroyl-sn-glycero-3-phosphate, sodium salt is a phospholipid extensively used as a component of liposome formulations and drug delivery systems.
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