Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V60066 | (6Z,16Z)-12-((Z)-Dec-4-enyl)docosa-6,16-dien-11-yl 5-(dimethylamino)pentanoate | 1450888-71-7 | Genevant CL1 is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2]. | |
V77379 | (R)-Chol-TPP | (R)-Chol-TPP is a mitochondria-targeted liposomal ligand for pH-redox reactions. | ||
V73412 | (Z)-KC02 | 1646795-60-9 | (Z)-KC02 is an inhibitor (blocker/antagonist) of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. | |
V90381 | 1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine | 36314-47-3 | 1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions and is commonly used to prepare liposomes and artificial membranes to study membrane dynamics. | |
V84244 | 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) | 5634-86-6 | ||
V90376 | 1,2-Diarachidoyl-sn-glycero-3-phosphocholine | 61596-53-0 | 1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid with saturated long-chain (20:0) arachidonic acid inserted at the sn-1 and sn-2 positions. | |
V87538 | 1,2-Dibehenoyl-sn-glycero-3-phosphocholine | 17688-29-8 | 1,2-Dibehenoyl-sn-glycero-3-phosphocholine (DBPC) is a phospholipid found in cell membranes. | |
V90347 | 1,2-Didecanoyl PC | 3436-44-0 | 1,2-Didecanoyl PC (1,2-Didecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine that can be introduced into single-chain mean field theory as a coarse-grained model of saturated phospholipids. | |
V90352 | 1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine | 253685-27-7 | 1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that shows very promising P-gp inhibitory effects at 0.3 mM concentration. | |
V90380 | 1,2-Dilauroyl-sn-glycero-3-phosphate sodium | 108321-06-8 | 1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid with medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions and can be used for the preparation of liposomes. | |
V83376 | 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE; 1,2-Dilauroyl-sn-glycero-3-PE) | 59752-57-7 | ||
V90344 | 1,2-Dilinoleoyl-sn-glycero-3-PC | 6542-05-8 | 1,2-Dilinoleoyl-sn-glycero-3-PC (Dilinoleoyllecithin) is a phospholipid. | |
V73459 | 1,2-DImyristoyl-rac-glycero-3-phosphocholine | 18656-38-7 | 1,2-DImyristoyl-rac-glycero-3-phosphocholine (DMPC) is a zwitterionic phospholipid chosen for simple eukaryotic cell membranes, mimicking the neutral charge of the eukaryotic plasma membrane surface. | |
V90377 | 1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium | 80724-31-8 | 1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions and can be used for the preparation of liposomes. | |
V90385 | 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium | 105405-50-3 | 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with a myristic acid tail (14:0) and contains a carboxylic acid (COOH) and an amine (NH2) in its head group, which can be used in the preparation of liposomes. | |
V74061 | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC; Dimyristoyl phosphatidylcholine) | 18194-24-6 | 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes and lipid bilayers. | |
V73466 | 1,2-Dioctanoyl-sn-glycero-3-phosphocholine | 19191-91-4 | 1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid extensively used as a component of liposome formulations and drug delivery systems. | |
V74058 | 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) | 90693-88-2 | 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium is a phosphoserine/phosphatidylserine alternative. | |
V89604 | 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine | 3922-61-0 | 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used to prepare liposomes and monolayers for the study of membrane permeability and monolayer viscosity, respectively. | |
V73451 | 1,2-Distaroyl-sn-glycero-3-phosphate sodium (distearoylphosphatidic acid) | 108321-18-2 | 1,2-Distaroyl-sn-glycero-3-phosphate, sodium salt is a phospholipid extensively used as a component of liposome formulations and drug delivery systems. |