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Dopamine Receptor

Dopamine Receptor

In the central nervous system (CNS) of vertebrates, dopamine receptors are a class of G protein-coupled receptors that are widely distributed. The main endogenous ligand for dopamine receptors is the neurotransmitter dopamine. Numerous neurological functions, including motivation, pleasure, cognition, memory, learning, and fine motor control, as well as the modulation of neuroendocrine signaling, are associated with dopamine receptors. Numerous neuropsychiatric disorders have abnormal dopamine receptor signaling and dopaminergic nerve function at their core.Dopamine receptors are therefore typical neurologic drug targets; psychostimulants are typically indirect agonists of dopamine receptors, whereas antipsychotics are frequently dopamine receptor antagonists. Dopamine receptors come in at least five different subtypes: D1, D2, D3, D4, and D5. The D2, D3, and D4 dopamine receptors are members of the D2-like family, whereas the D1 and D5 receptors belong to the D1-like family.

Dopamine Receptor related products

Structure Cat No. Product Name CAS No. Product Description
6-羟基多巴胺氢溴酸盐 V7444 6-OHDA HBr (Oxidopamine hydrobromide) 636-00-0 Oxidopamine (6-OHDA) HBr is an antagonist of the neurotransmitter dopamine.
L-多巴乙基酯盐酸盐 V20820 Etilevodopa HCl 39740-30-2 Etilevodopa HCl (TV-1203; Levodopa ethyl ester;L-Dopa ethyl ester; O-Ethyl-DOPA), the hydrochloride salt ofEtilevodopa, is a dopaminergic agent used for the treatment for Parkinsons disease.
ONC206 V14823 ONC206 1638178-87-6 ONC206 (ONC-206; ONC 206), an analogue of ONC201 (TRAIL inducer) and benzyl-flurobenzyl imipridone, is a novel, potent and selective antagonist of the D2-like dopamine receptors (DRD2/3/4) with a broad-spectrum of anticancer activity.
依匹唑哌 V17025 Brexpiprazole 913611-97-9 Brexpiprazole (formerlyOPC-34712;OPC34712; Rexulti)is a novel D2 dopamine partial agonist [also called serotonin-dopamine activity modulator (SDAM)] approved asanatypical antipsychotic drug.
依替左旋多巴 V20819 Etilevodopa 37178-37-3 Etilevodopa (TV-1203; Levodopa ethyl ester;L-Dopa ethyl ester; O-Ethyl-DOPA) is a dopaminergic agent used for the treatment for Parkinsons disease.
双氯芬酸盐酸盐 V3672 Diclofensine HCl 34041-84-4 Diclofensine HCl salt (also known as Ro-8-4650 HCl) is a novel and potent inhibitor of monoamine reuptake which blocks the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
盐酸泰必利 V14049 Tiapride HCl (Tiapridal) 51012-33-0 Tiapride HCl (Tiapridal),a benzamide derivative and an atypical neuroleptic agent, is a drug that selectively blocks D2 and D3 dopamine receptors in the brain.
盐酸舒托必利 V5703 Sultopride Hydrochloride 23694-17-9 Sultopride HCl (LIN-1418 HCl) is a selective antagonist of dopamine D2 receptors.
胃复安 V14604 Metoclopramide 364-62-5 Metoclopramide HCl is a potent and selective dopamine D2 receptor antagonist.
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