MAP kinase-activated protein kinase 2 (MAPKAPK2) is an enzyme that in humans is encoded by the MAPKAPK2 gene.It was discovered that MAPKAP kinase-2 (MK2) phosphorylates glycogen synthase at serine-7 and the serine in a peptide (GS peptide-1) designed to mimic the N-terminus of glycogen synthase.
A novel protein kinase called MAPKAP kinase-2 is triggered by mitogen-activated protein kinase. This MAPKAP kinase-2, also known as MAP kinase activated protein kinase-2, differs from S6 kinase-II (MAPKAP kinase-1) by how it reacts to inhibitors, the fact that it doesn't phosphorylate S6 peptides, and its amino acid sequence.
|MK2 Inhibitor III
|MK2 Inhibitor III is a potent cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) .
|MK2-IN-1 is a novel, potent,non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM).
|MK2-IN-1 HCl is a novel, potent, non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM).