MAP kinase-activated protein kinase 2 (MAPKAPK2) is an enzyme that in humans is encoded by the MAPKAPK2 gene.It was discovered that MAPKAP kinase-2 (MK2) phosphorylates glycogen synthase at serine-7 and the serine in a peptide (GS peptide-1) designed to mimic the N-terminus of glycogen synthase.

A novel protein kinase called MAPKAP kinase-2 is triggered by mitogen-activated protein kinase. This MAPKAP kinase-2, also known as MAP kinase activated protein kinase-2, differs from S6 kinase-II (MAPKAP kinase-1) by how it reacts to inhibitors, the fact that it doesn't phosphorylate S6 peptides, and its amino acid sequence.

MK2 related products

Structure Cat No. Product Name CAS No. Product Description
MK2 Inhibitor III V2340 MK2 Inhibitor III 724711-21-1 MK2-IN-3 is a potent and selective MAPKAP-K2 (MK-2) inhibitor with an IC50 value of 8.5 nM.
MK2-IN-1 V4323 MK2-IN-1 1314118-92-7 MK2-IN-1 is a novel, potent,non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM).
MK2-IN-1 HCL V4322 MK2-IN-1 HCL 1314118-94-9 MK2-IN-1 HCl is a novel, potent, non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM).
Peraquinsin V86267 Peraquinsin 35265-50-0
SMU-L11 V83477 SMU-L11
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