Acute respiratory infections are frequently brought on by RSV (Respiratory syncytial virus). RSV has the ability to take advantage of host immunity and trigger a significant inflammatory response that damages the lungs and spreads the virus. A and B are the two main antigenic subgroups of the one RSV serotype.
RSV is a non-segmented, negative-sense, single-stranded enveloped RNA virus that is a member of the Pneumovirinae subfamily of the Paramyxoviridae family and the Pneumovirus genus. Since two overlapping open reading frames in the M2 mRNA result in two different matrix proteins, M2-1 and M2-2, its 10 genes encode 11 proteins. The G glycoprotein, the F glycoprotein, and the SH protein are the three proteins that make up the viral envelope. The RSV virus has two non-structural proteins (NS1 and NS2) in addition to the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V109403 | 2-5A TEA | 72351-33-8 | 2-5A (2′,5′-ApApA; 2′,5′-trioligoadenylate; 5′-O-adenosyltriphosphate-(2′→5′)-adenosyl-(2′→5′)-adenosine)TEA is a 5′-triphosphorylated (2′,5′)oligoadenylate. |
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V88282 | Antiviral agent 58 | 939655-35-3 | Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2. |
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V110446 | AZD4316 | 1243324-08-4 | AZD-4316 is a respiratory syncytial virus (RSV) L protein inhibitor. |
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V117554 | CGR-50 | 3098857-57-6 | CGR-50 is a respiratory syncytial virus (RSV) fusion glycoprotein (F protein) inhibitor (EC50 value of 19.4 nM against RSV A2 strain in HEp-2 cells). |
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V119545 | Glarivibart | 3033697-08-1 | Glarevat is a humanized IgG1κ monoclonal antibody inhibitor that targets the respiratory syncytial virus (RSV) fusion F protein (RSV-F). |
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V88321 | GS-7682 | GS-7682 is an antiviral compound. | |
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V93224 | HRSV/HMPV-IN-1 | 2994287-06-6 | HRSV/HMPV-IN-1 (Compound 3) is a HRSV/HMPV inhibitor with EC50 values of < 0.2 μM and < 0.5 μM for human RSV-A and human MPV A2 TN/94-49, respectively. |
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V109209 | JNJ-6231 | JNJ-6231 is a long-acting RSV inhibitor. | |
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V88325 | JNJ-7184 | 2347368-51-6 | JNJ-7184 is a non-nucleoside inhibitor of RSV-Large (L) polymerase with pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. |
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V115434 | Oleoside dimethylester | 30164-95-5 | Dimethyl oleoside is a sericin compound found in the fruit of Ligustrum lucidum. |
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V6399 | RSV 604 | 676128-63-5 | RSV604 (A-60444) is an inhibitor (blocker/antagonist) of respiratory syncytial virus (RSV) replication. |
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V88324 | RSV-IN-10 | RSV-IN-10 (compound 6a) has antiviral activity against RSV with an IC50 value of 4 μM. | |
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V88322 | RSV-IN-11 | RSV-IN-11 (compound 10b) has antiviral activity against RSV with an IC50 value of 4 μM. | |
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V88326 | RSV-IN-13 | RSV-IN-13 (compound 5c) has antiviral activity against RSV with an EC50 value of 0.78 nM. |
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