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RSV

RSV

Acute respiratory infections are frequently brought on by RSV (Respiratory syncytial virus). RSV has the ability to take advantage of host immunity and trigger a significant inflammatory response that damages the lungs and spreads the virus. A and B are the two main antigenic subgroups of the one RSV serotype.
RSV is a non-segmented, negative-sense, single-stranded enveloped RNA virus that is a member of the Pneumovirinae subfamily of the Paramyxoviridae family and the Pneumovirus genus. Since two overlapping open reading frames in the M2 mRNA result in two different matrix proteins, M2-1 and M2-2, its 10 genes encode 11 proteins. The G glycoprotein, the F glycoprotein, and the SH protein are the three proteins that make up the viral envelope. The RSV virus has two non-structural proteins (NS1 and NS2) in addition to the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1.

RSV related products

Structure Cat No. Product Name CAS No. Product Description
2-5A V124392 2-5A 65954-93-0 2-5A is an RNase L activator, signaling mediator, and second messenger of innate immunity.
2-5A pentasodium solution (100 mM) V124393 2-5A pentasodium solution (100 mM) 2-5A pentasodium solution (100 mM) is a high-affinity (Ka=0.04 nM) RNase L binder.
2-5A TEA V109403 2-5A TEA 72351-33-8 2-5A (2′,5′-ApApA; 2′,5′-trioligoadenylate; 5′-O-adenosyltriphosphate-(2′→5′)-adenosyl-(2′→5′)-adenosine)TEA is a 5′-triphosphorylated (2′,5′)oligoadenylate.
Antiviral agent 58 V88282 Antiviral agent 58 939655-35-3 Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2.
AR-201 V129334 AR-201 AR-201 is a human IgG1 monoclonal antibody (mAb) that targets the fusion glycoprotein F0.
ASN-500 V129507 ASN-500 ASN-500 is a human monoclonal antibody (mAb) that targets the F/fusion glycoprotein F0.
Asvasiran sodium scrambled negative control V129559 Asvasiran sodium scrambled negative control The Asvasiran sodium scrambled negative control is a negative control for Asvasiran sodium with a scrambled sequence.
AZD4316 V110446 AZD4316 1243324-08-4 AZD-4316 is a respiratory syncytial virus (RSV) L protein inhibitor.
CGR-50 V117554 CGR-50 3098857-57-6 CGR-50 is a respiratory syncytial virus (RSV) fusion glycoprotein (F protein) inhibitor (EC50 value of 19.4 nM against RSV A2 strain in HEp-2 cells).
EVO-46120 V135480 EVO-46120 EVO-46120 is a human monoclonal antibody (mAb) that targets the F fusion glycoprotein F0.
EVO-46135 V135481 EVO-46135 EVO-46135 is a human monoclonal antibody (mAb) that targets the F/fusion glycoprotein F0.
Glarivibart V119545 Glarivibart 3033697-08-1 Glarevat is a humanized IgG1κ monoclonal antibody inhibitor that targets the respiratory syncytial virus (RSV) fusion F protein (RSV-F).
GS-646089 V136946 GS-646089 1770840-57-7 GS-646089 is a broad-spectrum antiviral nucleoside analog that exhibits significant inhibitory activity against respiratory syncytial virus (RSV), human metapneumovirus (hMPV), rhinovirus (enterovirus), and enteroviruses.
GS-7682 V88321 GS-7682 GS-7682 is an antiviral compound.
HRSV/HMPV-IN-1 V93224 HRSV/HMPV-IN-1 2994287-06-6 HRSV/HMPV-IN-1 (Compound 3) is a HRSV/HMPV inhibitor with EC50 values of < 0.2 μM and < 0.5 μM for human RSV-A and human MPV A2 TN/94-49, respectively.
IDB-002 V137811 IDB-002 IDB-002 is a human monoclonal antibody (mAb) that targets the F/fusion glycoprotein F0.
IN-002 V137913 IN-002 IN-002 is a human monoclonal antibody (mAb) that targets the F fusion glycoprotein F0.
JNJ-6231 V109209 JNJ-6231 JNJ-6231 is a long-acting RSV inhibitor.
JNJ-7184 V88325 JNJ-7184 2347368-51-6 JNJ-7184 is a non-nucleoside inhibitor of RSV-Large (L) polymerase with pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively.
JNJ-7950 V138269 JNJ-7950 3051902-04-3 JNJ-7950 (compound 5c) exhibits antiviral activity against respiratory syncytial virus (RSV) with an EC50 value of 0.78 nM.
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