Reverse transcription, also known as cDNA synthesis from an RNA template, is carried out by reverse transcriptases (RTs), an enzyme. To direct the synthesis of the first strand cDNA, reverse transcriptases (RTs) combine an RNA template with a brief primer complementary to the 3' end of the RNA.
Reverse transcriptase, an HIV enzyme, is blocked by nucleoside reverse transcriptase inhibitors (NRTIs). HIV reverse transcriptase is bound to and blocked by non-nucleoside reverse transcriptase inhibitors (NNRTIs). Reverse transcription is the process by which HIV turns RNA into DNA. HIV cannot replicate when reverse transcriptase and reverse transcription are blocked.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V54257 | (+)-Dihydrocalanolide A (DHCal A; NSC 678323) | 183904-53-2 | (+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally bioavailable, non-nucleoside reverse transcriptase inhibitor. |
|
V122307 | (Z)-Rilpivirine | 500287-94-5 | (Z)-Rilpivirine is the (Z)-isomer of rilpivirine. |
|
V122943 | 1,6-Di-O-galloyl-β-D-glucose | 23363-08-8 | 1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. |
|
V30705 | Cyclouridine (2,2'-Anhydrouridine) | 3736-77-4 | 2,2'-Anhydrouridine may be utilized in anti-tumor and anti-viral research. |
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V111563 | 5'-Azido-5'-deoxythymidine | 19316-85-9 | 5'-Azide-5'-deoxythymidine (compound 7) is a nucleoside analog and belongs to the reverse transcriptase inhibitors. |
|
V128415 | Agrocybin | 544-44-5 | Agrocybin is an antifungal peptide that has antifungal activity against a variety of fungi, but no inhibitory activity against bacteria. |
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V117207 | Alizarin complexone dihydrate | 455303-00-1 | Alizarin dihydrate is the dihydrate of alizarin complex. |
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V129467 | Artoheteronin | 2771017-28-6 | Artoheteronin is an isoprenoid coumarin found in jackfruit. |
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V129549 | Asterriquinone | 60696-52-8 | Asterriquinone is an asterriquinone analogue and belongs to the Grb-2 binding inhibitors. |
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V2865 | BMS-538203 | 543730-41-2 | BMS-538203 is a novel and highly efficient HIV integrase inhibitor that is being developed as an antiviral agent. |
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V1833 | BMS-707035 | 729607-74-3 | BMS-707035 is a novel, potent, specific, and reversible inhibitor of HIV-I integrase (IN) with IC50 of 15 nM. |
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V133199 | Dapivirine-d4 | 1309283-15-5 | Dapivirine-d4 is a deuterium-labeled form of dapivirine. |
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V13914 | Depulfavirine (RO-0335) | 867365-76-2 | RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor. |
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V133745 | Didanosine-13C2,15N | Didanosine-13C2,15N is didanosine labeled with 13C and 15N. | |
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V88314 | EFdA-TP tetralithium | EFdA-TP tetralithium is a potent nucleoside reverse transcriptase (RT) inhibitor. | |
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V135059 | Emtricitabine-d2 | Emtricitabine-d2 is the deuterated form of emtricitabine. | |
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V135441 | Etravirine-13C3 | 1189671-48-4 | Etravirine-13C3 is 13C-labeled etravirine. |
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V136906 | Gramine-d2 | 95415-84-2 | Gramine-d2 is a deuterium-labeled Gramine. |
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V137389 | HIV RT-IN-2 | 1909302-89-1 | HIV RT-IN-2 is an HIV reverse transcriptase inhibitor with an IC50 value of 1.2 μM against HIV-1 RT RNA-dependent DNA polymerase. |
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V79792 | HIV-1 inhibitor-49 | HIV-1 inhibitor-49 is an orally bioactive HIV-1 inhibitor and a HEPT analogue. |