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Glucagon Receptor

Glucagon Receptor

The G protein-coupled receptor family, which includes the glucagon receptor (GCGR), is crucial for regulating blood sugar levels. The class B G-protein coupled family of receptors includes the glucagon receptor, a 62 kDa protein that is activated by glucagon and coupled to G alpha i, Gs, and to a lesser extent G alpha q. Adenylate cyclase is activated and intracellular cAMP levels are raised when the receptor is stimulated. The GCGR gene in humans is responsible for encoding the glucagon receptor. The liver and kidneys are the primary sites of glucagon receptor expression, with smaller amounts of these receptors also present in the heart, adipose tissue, spleen, thymus, adrenal glands, pancreas, cerebral cortex, and gastrointestinal tract.

Glucagon Receptor related products

Structure Cat No. Product Name CAS No. Product Description
Albiglutide Fragment V3127 Albiglutide Fragment 782500-75-8 Albiglutide Fragment (GLP-1 fragment 7-36)is one copy of the 30-amino-acid sequence of modified human glucagon-like peptide-1 (GLP-1, fragment 7-36).
Danuglipron (PF-06882961) V37568 Danuglipron (PF-06882961) 2230198-02-2 Danuglipron (PF-06882961; PF06882961) is a novel, non-peptide, allosteric and orally bioavailable agonist of the glucagon-like peptide-1 receptor (GLP-1R).
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