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Opioid Receptor

Opioid Receptor

Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.

Opioid Receptor related products

Structure Cat No. Product Name CAS No. Product Description
(+)-N-Allylnormetazocine hydrochloride ((+)-SKF 10047 hydrochloride; (+)-N-Allyl-N-normetazocine hydrochloride) V69970 (+)-N-Allylnormetazocine hydrochloride ((+)-SKF 10047 hydrochloride; (+)-N-Allyl-N-normetazocine hydrochloride) 133005-41-1 (+)-N-Allylnormetazocine ((+)-SKF 10047) HCl is a benzoma opioid compound with psychotropic properties.
(+)-Norpropoxyphene maleate V121200 (+)-Norpropoxyphene maleate 159208-83-0 (+)-Norpropoxyphene maleate is an opioid metabolite and also a metabolite of propoxyphene.
(+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) V69941 (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) 67198-17-8 (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is an enantiomer of (-)-Trans-(1S,2S)-U-50488.
(+)-U-50488 hydrochloride ((+)-Trans-(1R,2R)-U-50488 hydrochloride) V69931 (+)-U-50488 hydrochloride ((+)-Trans-(1R,2R)-U-50488 hydrochloride) 114528-81-3 (+)-U-50488 (HCl) (+)-Trans-(1R,2R)-U-50488 HCl) is a κ opioid receptor agonist (activator) with lower activity than (-) trans Enantiomeric (-)-Trans-(1S,2S)-U-50488.
(-)-9-Hydroxycorynantheidine V104686 (-)-9-Hydroxycorynantheidine 425623-55-8 (-)-9-Hydroxycoronine (9-O-desmethylmethadone) is a 9-desmethyl analog of methadone and a selective partial agonist at the μ-opioid receptor.
(-)-P7C3-S243 V121154 (-)-P7C3-S243 1597443-57-6 (-)-P7C3-S243 is an orally effective neuroprotective agent that can cross the blood-brain barrier.
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) V69890 (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) 114528-79-9 (-)-U-50488 HCl ((-)-Trans-(1S,2S)-U-50488 HCl) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) with greater selectivity than μ opioid receptor (MOR) (Kd=430 nM).
(1R,2R)-U-50488 hydrochloride V69886 (1R,2R)-U-50488 hydrochloride 109620-49-7 (1R,2R)-U-50488 HCl is the absolute configuration of (±)-U-50488 HCl.
(D-Met2,Pro5)-Enkephalinamide V69932 (D-Met2,Pro5)-Enkephalinamide 63307-63-1 (D-Met2,Pro5)-Enkephalinamide is a potent opioid agonist with antinociceptive activity.
(R,R)-Suntinorexton V93135 (R,R)-Suntinorexton (R,R)-Suntinorexton is an isomer of Suntinorexton.
(Rac)-SNC80 ((Rac)-NIH 10815) V69922 (Rac)-SNC80 ((Rac)-NIH 10815) 1217643-87-2 (Rac)-SNC80 is the racemate of SNC80.
(S)-MCOPPB V122189 (S)-MCOPPB 1108147-70-1 (S)-MCOPPB is the S-isomer of MCOPPB.
(S,S)-J-113397 V69902 (S,S)-J-113397 256640-46-7 (S,S)-J-113397 is an enantiomer of J-113397.
(±)-U-50488 V109003 (±)-U-50488 67198-13-4 (±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective κ opioid receptor agonist.
(±)-U-50488 hydrate hydrochloride ((±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride) V77396 (±)-U-50488 hydrate hydrochloride ((±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride) (±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate HCl is a κ opioid receptor agonist.
1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid V107548 1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid 1535166-43-8 1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid is a structural analog of cannabinoid metabolites.
1-Naphthyl U-47700 V123636 1-Naphthyl U-47700 1-Naphthyl U-47700 is an α-isomer.
2,4-Difluoro U-48800 hydrochloride V104047 2,4-Difluoro U-48800 hydrochloride 2740304-36-1 2,4-Difluoro U-48800 hydrochloride is a compound classified as an opioid.
2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol V107547 2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol 63880-43-3 2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol is a structural analog of opioid compounds.
2-Naphthyl U-47700 V104539 2-Naphthyl U-47700 67579-80-0 2-Naphthyl U-47700 is an opioid compound.
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