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Opioid Receptor

Opioid Receptor

Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.

Opioid Receptor related products

Structure Cat No. Product Name CAS No. Product Description
(+)-N-Allylnormetazocine hydrochloride ((+)-SKF 10047 hydrochloride; (+)-N-Allyl-N-normetazocine hydrochloride) V69970 (+)-N-Allylnormetazocine hydrochloride ((+)-SKF 10047 hydrochloride; (+)-N-Allyl-N-normetazocine hydrochloride) 133005-41-1 (+)-N-Allylnormetazocine ((+)-SKF 10047) HCl is a benzoma opioid compound with psychotropic properties.
(+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) V69941 (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) 67198-17-8 (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is an enantiomer of (-)-Trans-(1S,2S)-U-50488.
(+)-U-50488 hydrochloride ((+)-Trans-(1R,2R)-U-50488 hydrochloride) V69931 (+)-U-50488 hydrochloride ((+)-Trans-(1R,2R)-U-50488 hydrochloride) 114528-81-3 (+)-U-50488 (HCl) (+)-Trans-(1R,2R)-U-50488 HCl) is a κ opioid receptor agonist (activator) with lower activity than (-) trans Enantiomeric (-)-Trans-(1S,2S)-U-50488.
(-)-9-Hydroxycorynantheidine V104686 (-)-9-Hydroxycorynantheidine 425623-55-8 (-)-9-Hydroxycoronine (9-O-desmethylmethadone) is a 9-desmethyl analog of methadone and a selective partial agonist at the μ-opioid receptor.
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) V69890 (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) 114528-79-9 (-)-U-50488 HCl ((-)-Trans-(1S,2S)-U-50488 HCl) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) with greater selectivity than μ opioid receptor (MOR) (Kd=430 nM).
(1R,2R)-U-50488 hydrochloride V69886 (1R,2R)-U-50488 hydrochloride 109620-49-7 (1R,2R)-U-50488 HCl is the absolute configuration of (±)-U-50488 HCl.
(D-Met2,Pro5)-Enkephalinamide V69932 (D-Met2,Pro5)-Enkephalinamide 63307-63-1 (D-Met2,Pro5)-Enkephalinamide is a potent opioid agonist with antinociceptive activity.
(R,R)-Suntinorexton V93135 (R,R)-Suntinorexton (R,R)-Suntinorexton is an isomer of Suntinorexton.
(Rac)-SNC80 ((Rac)-NIH 10815) V69922 (Rac)-SNC80 ((Rac)-NIH 10815) 1217643-87-2 (Rac)-SNC80 is the racemate of SNC80.
(S,S)-J-113397 V69902 (S,S)-J-113397 256640-46-7 (S,S)-J-113397 is an enantiomer of J-113397.
(±)-U-50488 hydrate hydrochloride ((±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride) V77396 (±)-U-50488 hydrate hydrochloride ((±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride) (±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate HCl is a κ opioid receptor agonist.
1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid V107548 1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid 1535166-43-8 1-(5-Fluoropentyl)-1H-indazole-3-carboxylic acid is a structural analog of cannabinoid metabolites.
2,4-Difluoro U-48800 hydrochloride V104047 2,4-Difluoro U-48800 hydrochloride 2740304-36-1 2,4-Difluoro U-48800 hydrochloride is a compound classified as an opioid.
2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol V107547 2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol 63880-43-3 2-(Di-sec-butylamino)-1-(1-(2-fluorobenzyl)-1H-pyrrol-2-yl)ethan-1-ol is a structural analog of opioid compounds.
2-Naphthyl U-47700 V104539 2-Naphthyl U-47700 67579-80-0 2-Naphthyl U-47700 is an opioid compound.
22-Thiocyanatosalvinorin A V104215 22-Thiocyanatosalvinorin A 1174223-49-4 Salvinoline 22-thiocyanate A (RB-64) is a potent and selective kappa opioid receptor agonist with EC50 of 0.077 nM.
3,4-Difluoro isopropyl U-47700 V104046 3,4-Difluoro isopropyl U-47700 2752265-46-4 3,4-Difluoroisopropyl U-47700 is a compound classified as an opioid.
3,4-Difluoro U-49900 hydrochloride V107546 3,4-Difluoro U-49900 hydrochloride 2743078-88-6 3,4-Difluoro-U-49900 hydrochloride is an opioid compound.
3,4-Difluoro U-50488 hydrochloride V103253 3,4-Difluoro U-50488 hydrochloride 1339332-99-8 3,4-Difluoro-U-50488 hydrochloride is a compound classified as an opioid.
3,4-Difluoro-N,N-didesmethyl U-47700 TFA V107545 3,4-Difluoro-N,N-didesmethyl U-47700 TFA 2751977-98-5 3,4-Difluoro-N,N-didemethyl U-47700 TFA is a compound classified as Utopian.
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