5-HT Receptor

5-HT Receptor

5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems.5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, and 5-HT7 are the types. Both excitatory and inhibitory neurotransmission is mediated by them. The neurotransmitter serotonin, which serves as their inherently ligand, stimulates the serotonin receptors. Numerous neurotransmitters and hormones are released in response to stimulation of the serotonin receptors. Numerous biological and neurological functions, including aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation, are influenced by serotonin receptors. Many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens are among the pharmaceuticals that target the serotonin receptors.

5-HT Receptor related products

Structure Cat No. Product Name CAS No. Product Description
V71145 (+)-Norfenfluramine ((S)-1-(3-(trifluoromethyl)phenyl)propan-2-amine) 19036-73-8
V71147 (+)-Norfenfluramine hydrochloride 37936-89-3
V71190 (-)-Eseroline fumarate (Eseroline fumarate) 70310-73-5
V3896 (R,R)-Palonosetron Hydrochloride 135729-75-8 (R,R)-Palonosetron Hydrochloride isthe active R,R-enantiomer of Palonosetron HCl (RS25259, RS-25259 197; trade name: Aloxi and Akynzeo) which is a 5-HT3 antagonist approved in 2018 in the prevention and treatment of chemotherapy-induced nausea and vomiting.
V71157 (Rac)-WAY-161503 hydrochloride 276695-22-8
V71196 (S)-Bexicaserin 2035818-21-2
V77357 (S)-Renzapride ((S)-BRL 24924)
V71200 3,4-DihydroNaratriptan 121679-20-7
V71181 4,4-Diphenylbutylamine hydrochloride 22101-90-2
V71205 4-Butyl-alpha-agarofuran (Buagafuran; Buagarofuran) 272126-07-5
V71151 4F 4PP oxalate 144734-36-1
V71140 5-Carboxamidotryptamine (5-CT) 74885-09-9
V71125 5-Carboxamidotryptamine maleate (5-CT maleate) 74885-72-6
V71178 5-HT1A modulator 2 hydrochloride 3880-76-0
V71194 5-HT2 agonist-1 free base 2708279-77-8
V71225 5-HT2A receptor agonist-1 2698331-34-7
V71198 5-HT2A receptor agonist-3 1391499-52-7
V71218 5-HT2A&5-HT2C agonist-1 1640-02-4
V71186 5-HT2agonist-1 2708279-78-9
V71201 5-HT2C agonist-3 2104810-18-4
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