It has been established that the Ca2+/calmodulin-dependent kinase (CaMK) family is an important mediator in living things and numerous biological processes.
CaMK II is a multifunctional protein kinase that phosphorylates and modifies the function of a wide range of substrates in the cytoplasm in response to calcium and calmodulin. It has been discovered that the cAMP-response element binding protein (CREB) pathway controls the RANKL-induced osteoclast formation through the CaMK II pathway.
Intracellular calciumol/L has been repeatedly shown to be crucial among the many signaling pathways of proliferation. Calciumol/L activates the CaMKs, a family of structurally related serine/threonine protein kinases, including CaMKI-IV, in the cytoplasm by binding to calmodulin. Cell cycle, apoptosis, gene expression, and neurotransmission are just a few of the physiological processes that CaMKII, a multifunctional protein kinase, is constantly involved in.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V32904 | A-484954 | 142557-61-7 | A-484954 (A484954; A 484954) is a highly selective,cell-permeable andATP-competitive eukaryotic elongation factor-2 (eEF2) inhibitor with potential antitumor activity. |
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V77730 | AC3-I, myristoylated (Autocamtide-3 Derived Inhibitory Peptide) | AC3-I, myristoylated is a biologically active peptide. | |
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V71550 | Autocamtide-3 | 142828-10-2 | Autocamtide-3 is a 13 amino acid (AA) peptide containing Thr287 and is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. |
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V77224 | Autocamtide-3 acetate | Autocamtide-3 acetate is a 13 amino acid (AA) peptide containing Thr287 and is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. | |
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V52993 | Cabamiquine succinate (DDD107498 succinate; DDD-498 succinate; M5717 succinate) | 2444781-71-7 | Cabamiquine (DDD107498) succinate is a potent, orally bioavailable antimalarial agent that can inhibit multiple stages of the parasite life cycle, with EC50 of 1 nM against P. falciparum 3D7. |
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V71545 | Calmodulin Dependent Protein Kinase Substrate | 82801-68-1 | Calmodulin Dependent Protein Kinase Substrate is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
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V71549 | Calmodulin Dependent Protein Kinase Substrate Analog | 123067-01-6 | Calmodulin Dependent Protein Kinase Substrate Analog is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
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V78611 | Calmodulin Kinase IINtide, Myristoylated (Myr-CaMKIINtide) | Calmodulin Kinase IINtide, Myristoylated (Myr-CaMKIINtide) is a selective and noncompetitive CaMKII inhibitor. | |
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V87788 | CaMKI(299-320) | CaMKI (299-320) refers to a peptide consisting of amino acid residues 299 to 320 of calcium/calmodulin-dependent protein kinase I (CaMKI). | |
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V71547 | CaMKII inhibitory peptide KIIN (Calmodulin Kinase IINtide; CaM-KIIN; CaM-KIINβ) | 508181-45-1 | CaMKII inhibitory peptide KIIN is a potent inhibitor of CaMKII. |
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V3429 | CaMKII-IN-1 | 1208123-85-6 | CaMKII-IN-1, a5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine analog, is a novel, potent and highly selective inhibitor of CaMKII (Ca2+/calmodulin-dependent protein kinase II) inhibitor with IC50 of 63 nM. |
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V71544 | CS587 | 2388506-69-0 | CS587 is a specific inhibitor of CaMK1D and is neurotoxic at 10 μM. |
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V1298 | KN-62 | 127191-97-3 | KN-62 (KN62; KN 62) is a potent, selective, cell-permeable and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with potential anticancer activity. |
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V2578 | KN-92 | 176708-42-2 | KN-92 is an inactive derivative of KN-93. |
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V2803 | KN-92 Hydrochloride | 1431698-47-3 | KN-92 Hydrochloride, the hydrochloride salt of KN-92, is an inactive derivative of KN-93. |
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V2802 | KN-92 Phosphate | 1135280-28-2 | KN-92 Phosphate, the phosphate salt of KN-92, is an inactive derivative of KN-93. |
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V2580 | KN-93 | 139298-40-1 | KN-93 is a potent,cell-permeable, reversible and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, and withno remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities. |
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V2579 | KN-93 HCl | 1956426-56-4 | KN-93 HClis a potent,cell-permeable, reversible and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, and withno remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities. |
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V1299 | KN-93 Phosphate | 1188890-41-6 | KN-93 Phosphate (KN 93; KN93), the phosphate salt of KN-93, is a potent, cell-permeable and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with potential anti-Parkinsons disease and anticancer activity. |
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V13777 | Lavendustin C | 125697-93-0 | Lavendustin C, formerly known as HDBA and NSC 666251, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 of 0.012 µM. |
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