It has been established that the Ca2+/calmodulin-dependent kinase (CaMK) family is an important mediator in living things and numerous biological processes.
CaMK II is a multifunctional protein kinase that phosphorylates and modifies the function of a wide range of substrates in the cytoplasm in response to calcium and calmodulin. It has been discovered that the cAMP-response element binding protein (CREB) pathway controls the RANKL-induced osteoclast formation through the CaMK II pathway.
Intracellular calciumol/L has been repeatedly shown to be crucial among the many signaling pathways of proliferation. Calciumol/L activates the CaMKs, a family of structurally related serine/threonine protein kinases, including CaMKI-IV, in the cytoplasm by binding to calmodulin. Cell cycle, apoptosis, gene expression, and neurotransmission are just a few of the physiological processes that CaMKII, a multifunctional protein kinase, is constantly involved in.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V32904 | A-484954 | 142557-61-7 | A-484954 (A484954; A 484954) is a highly selective,cell-permeable andATP-competitive eukaryotic elongation factor-2 (eEF2) inhibitor with potential antitumor activity. |
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V77730 | AC3-I, myristoylated (Autocamtide-3 Derived Inhibitory Peptide) | AC3-I, myristoylated is a biologically active peptide. | |
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V71550 | Autocamtide-3 | 142828-10-2 | Autocamtide-3 is a 13 amino acid (AA) peptide containing Thr287 and is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. |
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V77224 | Autocamtide-3 acetate | Autocamtide-3 acetate is a 13 amino acid (AA) peptide containing Thr287 and is a selective CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK) substrate. | |
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V119016 | Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase | CAMK2 is involved in the regulation of cellular processes in various tissues. | |
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V52993 | Cabamiquine succinate (DDD107498 succinate; DDD-498 succinate; M5717 succinate) | 2444781-71-7 | Cabamiquine (DDD107498) succinate is a potent, orally bioavailable antimalarial agent that can inhibit multiple stages of the parasite life cycle, with EC50 of 1 nM against P. falciparum 3D7. |
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V71545 | Calmodulin Dependent Protein Kinase Substrate | 82801-68-1 | Calmodulin Dependent Protein Kinase Substrate is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
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V71549 | Calmodulin Dependent Protein Kinase Substrate Analog | 123067-01-6 | Calmodulin Dependent Protein Kinase Substrate Analog is a Ca2+- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. |
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V78611 | Calmodulin Kinase IINtide, Myristoylated (Myr-CaMKIINtide) | Calmodulin Kinase IINtide, Myristoylated (Myr-CaMKIINtide) is a selective and noncompetitive CaMKII inhibitor. | |
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V118862 | CaMK1β Recombinant Human Active Protein Kinase | CaMK1 is present in multiple cell types and may be involved in a variety of cellular processes. | |
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V118921 | CaMK2α Recombinant Human Active Protein Kinase | CAMK2 is involved in the regulation of cellular processes in various tissues. | |
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V118897 | CaMK2β Recombinant Human Active Protein Kinase | CAMK2 is involved in the regulation of cellular processes in various tissues. | |
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V87788 | CaMKI(299-320) | 205598-38-5 | CaMKI (299-320) refers to a peptide consisting of amino acid residues 299 to 320 of calcium/calmodulin-dependent protein kinase I (CaMKI). |
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V71547 | CaMKII inhibitory peptide KIIN (Calmodulin Kinase IINtide; CaM-KIIN; CaM-KIINβ) | 508181-45-1 | CaMKII inhibitory peptide KIIN is a potent inhibitor of CaMKII. |
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V3429 | CaMKII-IN-1 | 1208123-85-6 | CaMKII-IN-1, a5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine analog, is a novel, potent and highly selective inhibitor of CaMKII (Ca2+/calmodulin-dependent protein kinase II) inhibitor with IC50 of 63 nM. |
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V108965 | CaMKII-IN-3 | 2765717-63-1 | CaMKII-IN-3 (Example 321) is a CaMKII inhibitor with an IC50 < 10 nM. |
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V119442 | CaMKIIδ-IN-1 | 1026029-18-4 | CaMKIIδ-IN-1 (compound 15e) is a pyrimidine-based CaMKIIδ inhibitor with an IC50 value of 12 nM. |
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V113830 | CaMKIIδ-IN-1 hydrochloride | CaMKIIδ-IN-1 (compound 15e) hydrochloride is a pyrimidine CaMKIIδ inhibitor with an IC50 value of 12 nM. | |
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V118927 | CAMKK2 Recombinant Human Active Protein Kinase | CaMKK2 is a serine/threonine protein kinase and a core component of the Ca2+-calmodulin activation signaling pathway. | |
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V71544 | CS587 | 2388506-69-0 | CS587 is a specific inhibitor of CaMK1D and is neurotoxic at 10 μM. |
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