The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V54276 | (-)-Rabdosiin | 119152-54-4 | (-)-Rabdosiin is a novel phenolic marker discovered from Symphytum officinale L. |
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V54273 | (2RS)-FPMPA | 135295-27-1 | (2RS)-FPMPA may be utilized to prepare antiretroviral reagents against HIV-1 and HIV-2. |
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V77391 | (2S,5S)-Censavudine ((2S,5S)-OBP-601; (2S,5S)-BMS-986001) | (2S,5S)-Censavudine ((2S,5S)-OBP-601) is the (2S,5S)-enantiomer of Censavudine. | |
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V54295 | (Cys47)-HIV-1 tat Protein (47-57) | 627079-23-6 | (Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation capabilities and may be utilized to derivatize the surface of magnetically active molecules and facilitate their uptake into target cells. |
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V40146 | (S)-Tenofovir | 147127-19-3 | (S)-Tenofovir [known also as (S)-GS 1278], the S-enantiomer of Tenofovir and a less active isomer,is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV). |
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V53005 | (Z)-9-Propenyladenine ((Z)-Mutagenic Impurity of Tenofovir Disoproxil) | 1464851-21-5 | (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. |
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V88714 | 2'-Deoxy-2'-fluoroarabinoadenosine | 20227-41-2 | 2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analog with antiviral activity against human immunodeficiency virus (HIV). |
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V91149 | 2-Bromoaldisine | 96562-96-8 | 2-Bromoaldisine is a pyrrole alkaloid isolated from Stylissa carter. |
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V54297 | 2F5 epitope | 470704-11-1 | The 2F5 epitope is a fragment of the peptide gp41 (659-671) that contains the complete epitope of one of three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates, and is the only such contiguous epitope. |
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V2383 | 3-Phenanthrenebutyric acid | 13728-56-8 | HIV-1 Nef-IN-1 is an inhibitor (blocker/antagonist) of HIV-1 Nef protein that effectively competes for the Nef-SH3Hck interaction with Kd of 6.7 μM. |
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V76170 | 4-Deoxy-4α-phorbol | 37415-57-9 | 4-Deoxy-4α-phorbol is a tetracyclic diterpenoid found in E. |
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V54306 | 7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) | 111869-49-9 | 7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2',3'-dideoxynucleoside 5'-triphosphate that can inhibit HIV-1 reverse transcriptase with Ki of 25 nM. |
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V32833 | 9-Propenyladenine | 1446486-33-4 | 9-Propenyladenine is an impurity found in tenofovir disoproxil fumarate with mutagenicity. |
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V54254 | Alvircept sudotox (U 85855) | 137487-62-8 | Alvircept sudotox is a recombinant CD4 derived from Pneumonas aeruginosa exotoxin A. |
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V40231 | Amphotericin B methyl ester | 36148-89-7 | Amphotericin B methyl ester, the methyl ester derivativeof Amphotericin B (A-634250), is a cholesterol-binding compound with potent antifungal activity. |
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V52422 | Amphotericin B methyl ester hydrochloride | 35375-29-2 | Amphotericin B methyl ester HCl is the methyl ester analogue of the polyene antibiotic Amphotericin B (A634250). |
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V77253 | Anti-Mouse CD4 Antibody (YTS 191) | Anti-Mouse CD4 Antibody (YTS 191) is an anti-mouse CD4 IgG2b antibody inhibitor, and the host is Rat. | |
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V85460 | Antiviral agent 45 | ||
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V78085 | Antiviral agent 9 | The EC50 of antiviral compound 9 against HIV-1 reaches picomolar concentration (0.006 nM), and the selectivity index (SI) is nearly 300 times higher than that of tenofovir alafenamide fumarate (TAF). | |
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V54245 | Apelin-36(rat, mouse) | 230299-95-3 | Apelin-36 (rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. |
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