| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V1771 | Aliskiren Hemifumarate (CGP 60536) | 173334-58-2 | Aliskiren hemifumarate (CGP-60536; CGP60536; Rasilez; SPP100; SPP-100;Tekturna), the hemifumarate salt form of Aliskiren, is a potent and direct renin inhibitor with antihypertensive activity. |
|
V1790 | Azilsartan (TAK-536) | 147403-03-0 | Azilsartan(TAK-536; TAK536;Edarbi;Ipreziv) is a potent andorally bioavailable angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effects. |
|
V1793 | Azilsartan Medoxomil (TAK 491) | 863031-21-4 | Azilsartan Medoxomil (formerly also known as TAK-491), the ester prodrugof Azilsartan (TAK-536),is a potent andorally bioavailable angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM. |
|
V1787 | Benazepril HCl (CGS14824A) | 86541-74-4 | Benazepril HCl (formerly CGS 14824A;CGS-14824-A;Briem; Cibacène; Cibacen; Labopal; Lotensin), the hydrochloride salt of Benazepril which is a prodrug that can bemetabolized to its active formbenazeprilat,is a potent angiotensin I converting enzyme (ACE) inhibitor that has beenwidelyused primarily in treatment of hypertension. |
|
V1772 | Candesartan (CV 11974) | 139481-59-7 | Candesartan (also known as CV-11974; Blopress, Atacand, Amias, Ratacand)is an approved antihypertensive drug acting as an AT II/angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
V1784 | Candesartan Cilexetil (CV 11974) | 145040-37-5 | Candesartan Cilexetil (formerly TCV-116;CV11974; CV-11974; Atacand), an ester prodrug ofCandesartan,is an antihypertensive drug acting as an AT II/angiotensin II receptor antagonistwith anti-hypertensive effects. |
|
V1792 | Captopril (SQ-14534; SA333) | 62571-86-2 | Captopril (SQ 14225; SA333)is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. |
|
V1794 | Cilazapril Monohydrate (Ro 31-2848) | 92077-78-6 | Cilazapril Monohydrate (Ro 31-2848) is a potent angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. |
|
V1788 | Enalapril Maleate (MK-421) | 76095-16-4 | Enalapril maleate (formerly MK-421; MK421; Glioten; Vasotec; Baripril; Renitec; Renitek), the maleate salt of enalapril, is a potent nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor widely used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
|
V1774 | Enalaprilat Dihydrate (MK-422) | 84680-54-6 | EnalaprilatDihydrate(also known as MK422; MK 422; MK-422; Epaned, Vasotec, Vasotec IV), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor approved for the treatment of hypertension, diabetic nephropathy, and chronic heart failure. |
|
V1797 | Eprosartan Mesylate (SKF-108566J) | 144143-96-4 | Eprosartan Mesylate(SKF-108566J) is a potent and nonpeptide angiotensin II receptor antagonist with IC50 of 9.2 and 3.9 nM in rat and human adrenal cortical membranes, respectively. |
|
V1796 | Fosinopril Sodium (SQ28555) | 88889-14-9 | Fosinopril Sodium (also known as SQ28555), the ester prodrug offosinoprilat, is a potent angiotensin-converting enzyme (ACE) inhibitor that is used for the treatment of hypertension and some types of chronic heart failure. |
|
V1789 | Imidapril HCl (TA-6366) | 89396-94-1 | Imidapril HCl (TA-6366; TA-6366; Tanatril), the hydrochloride salt of imidapril,is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, approved in 1993 for use as an antihypertensive drug and for the treatment of chronic heart failure. |
|
V1776 | Irbesartan (SR-47436; BMS-186295) | 138402-11-6 | Irbesartan (formerly known as SR47436; BMS186295;SR-47436; BMS-186295; Avapro, Aprovel, Karvea) is a highly potent and specific angiotensin II type 1 (AT II-1) receptor antagonist/ARB approved as an antihypertension drug. |
|
V1778 | LCZ696 (Sacubitril-Valsartan) | 936623-90-4 | LCZ696 (LCZ-696; LCZ 696; Entresto; Sacubitril mixture with Valsartan), the combination of valsartan with sacubitril in 1:1 molar ratio, is an orally bioavailable and dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) approved in 2015 for the treatment of hypertension and heart failure. |
|
V1786 | Lisinopril (MK-521) | 76547-98-3 | Lisinopril (MK-521; MK521; Zestril; Linopril; Lisipril) is a potent angiotensin-converting enzyme (ACE) inhibitor approved for use in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes. |
|
V1773 | Losartan Potassium (DuP 753) | 124750-99-8 | Losartan Potassium (formerly DuP-753; MK-954; DuP753;MK954;Cozaar; Lorzaar; Losaprex), thepotassium salt of losartan, is an oral, selective, and non-peptide angiotensin II receptor antagonist approved as an antihypertensive drug. |
|
V1795 | Moexipril HCl (RS-10085) | 82586-52-5 | Moexipril HCl (RS-10085) is a potent and orally bioactive nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure. |
|
V1781 | Olmesartan Medoxomil (CS 866) | 144689-63-4 | Olmesartan Medoxomil (formerly CS-866;Olmetec; Azor; Benicar;Olsertain), the medoxomil ester prodrug form of Olmesartan, is a potent and selective angiotensin II type 1/AT1 receptor antagonist with anti-hypertensive effects. |
|
V1779 | PD123319 | 130663-39-7 | PD 123319 [PD-123319; PD123319; (S)-(+)-PD 123319] is a novel, potent, and selective AT2 (angiotensin II) receptor antagonist with anti-hypertensive effects. |
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