RAAS

RAAS

RAAS related products

Structure Cat No. Product Name CAS No. Product Description
V1771 Aliskiren Hemifumarate (CGP 60536) 173334-58-2 Aliskiren hemifumarate (CGP-60536; CGP60536; Rasilez; SPP100; SPP-100;Tekturna), the hemifumarate salt form of Aliskiren, is a potent and direct renin inhibitor with antihypertensive activity.
V1790 Azilsartan (TAK-536) 147403-03-0 Azilsartan(TAK-536; TAK536;Edarbi;Ipreziv) is a potent andorally bioavailable angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effects.
V1793 Azilsartan Medoxomil (TAK 491) 863031-21-4 Azilsartan Medoxomil (formerly also known as TAK-491), the ester prodrugof Azilsartan (TAK-536),is a potent andorally bioavailable angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM.
V1787 Benazepril HCl (CGS14824A) 86541-74-4 Benazepril HCl (formerly CGS 14824A;CGS-14824-A;Briem; Cibacène; Cibacen; Labopal; Lotensin), the hydrochloride salt of Benazepril which is a prodrug that can bemetabolized to its active formbenazeprilat,is a potent angiotensin I converting enzyme (ACE) inhibitor that has beenwidelyused primarily in treatment of hypertension.
V1772 Candesartan (CV 11974) 139481-59-7 Candesartan (also known as CV-11974; Blopress, Atacand, Amias, Ratacand)is an approved antihypertensive drug acting as an AT II/angiotensin II receptor antagonist with IC50 of 0.26 nM.
V1784 Candesartan Cilexetil (CV 11974) 145040-37-5 Candesartan Cilexetil (formerly TCV-116;CV11974; CV-11974; Atacand), an ester prodrug ofCandesartan,is an antihypertensive drug acting as an AT II/angiotensin II receptor antagonistwith anti-hypertensive effects.
V1792 Captopril (SQ-14534; SA333) 62571-86-2 Captopril (SQ 14225; SA333)is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.
V1794 Cilazapril Monohydrate (Ro 31-2848) 92077-78-6 Cilazapril Monohydrate (Ro 31-2848) is a potent angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
V1788 Enalapril Maleate (MK-421) 76095-16-4 Enalapril maleate (formerly MK-421; MK421; Glioten; Vasotec; Baripril; Renitec; Renitek), the maleate salt of enalapril, is a potent nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor widely used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
V1774 Enalaprilat Dihydrate (MK-422) 84680-54-6 EnalaprilatDihydrate(also known as MK422; MK 422; MK-422; Epaned, Vasotec, Vasotec IV), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor approved for the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
V1797 Eprosartan Mesylate (SKF-108566J) 144143-96-4 Eprosartan Mesylate(SKF-108566J) is a potent and nonpeptide angiotensin II receptor antagonist with IC50 of 9.2 and 3.9 nM in rat and human adrenal cortical membranes, respectively.
V1796 Fosinopril Sodium (SQ28555) 88889-14-9 Fosinopril Sodium (also known as SQ28555), the ester prodrug offosinoprilat, is a potent angiotensin-converting enzyme (ACE) inhibitor that is used for the treatment of hypertension and some types of chronic heart failure.
V1789 Imidapril HCl (TA-6366) 89396-94-1 Imidapril HCl (TA-6366; TA-6366; Tanatril), the hydrochloride salt of imidapril,is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, approved in 1993 for use as an antihypertensive drug and for the treatment of chronic heart failure.
V1776 Irbesartan (SR-47436; BMS-186295) 138402-11-6 Irbesartan (formerly known as SR47436; BMS186295;SR-47436; BMS-186295; Avapro, Aprovel, Karvea) is a highly potent and specific angiotensin II type 1 (AT II-1) receptor antagonist/ARB approved as an antihypertension drug.
V1778 LCZ696 (Sacubitril-Valsartan) 936623-90-4 LCZ696 (LCZ-696; LCZ 696; Entresto; Sacubitril mixture with Valsartan), the combination of valsartan with sacubitril in 1:1 molar ratio, is an orally bioavailable and dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) approved in 2015 for the treatment of hypertension and heart failure.
V1786 Lisinopril (MK-521) 76547-98-3
V1773 Losartan Potassium (DuP 753) 124750-99-8 Losartan Potassium (formerly DuP-753; MK-954; DuP753;MK954;Cozaar; Lorzaar; Losaprex), thepotassium salt of losartan, is an oral, selective, and non-peptide angiotensin II receptor antagonist approved as an antihypertensive drug.
V1795 Moexipril HCl (RS-10085) 82586-52-5 Moexipril HCl (RS-10085) is a potent and orally bioactive nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.
V1781 Olmesartan Medoxomil (CS 866) 144689-63-4 Olmesartan Medoxomil (formerly CS-866;Olmetec; Azor; Benicar;Olsertain), the medoxomil ester prodrug form of Olmesartan, is a potent and selective angiotensin II type 1/AT1 receptor antagonist with anti-hypertensive effects.
V1779 PD123319 130663-39-7 PD 123319 [PD-123319; PD123319; (S)-(+)-PD 123319] is a novel, potent, and selective AT2 (angiotensin II) receptor antagonist with anti-hypertensive effects.
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