Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72225 | (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA) | 13382-47-3 | (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the major urinary metabolite of 1,4-Dioxane. |
|
V72236 | (25R)-12α-Hydroxyspirost-4-en-3-one | 50888-50-1 | (25R)-12α-Hydroxyspirost-4-en-3-one is a minor metabolite generated by Nocardia globerula on Hecogenin. |
|
V32701 | (2S,4S)-Sacubitril | 149709-63-7 | 2S,4S-Sacubitril is an impurity of Sacubitril (AHU 377; AHU377;AHU-377), which is a US FDA approved drug used in combination with valsartan (trade name Entrosto for the combo)for the treatment of heart failure. |
|
V72169 | (3,4,5-Trimethoxyphenyl)acetic-2,2 Acid-d2 | 344299-45-2 | (3,4,5-Trimethoxyphenyl)acetic-2,2 Acid-d2 is the deuterium labelled form of 3,4,5-Trimethoxyphenylacetic acid. |
|
V72147 | (E)-10-Hydroxynortriptyline (E-10-OH-NT) | 47132-16-1 | (E)-10-Hydroxynortriptyline (E-10-OH-NT) is the metabolite of Nortriptyline. |
|
V72206 | (R)-(-)-O-Desmethyl Venlafaxine-d6 ((R)-O-Desmethyl Venlafaxine-d6) | 1062609-96-4 | (R)-(-)-O-Desmethyl Venlafaxine-d6 is the deuterated form of (R)-(-)-O-Desmethyl Venlafaxine. |
|
V72217 | (R)-tert-OMe-byakangelicin | 89560-97-4 | (R)-tert-OMe-byakangelicin is a furanocoumarin with inhibitory activity on hepatic drug metabolizing enzyme (DME) activity. |
|
V72293 | (Rac)-Mono(3,5,5-trimethylhexyl) phthalate | 297182-83-3 | (Rac)-Mono(3,5,5-trimethylhexyl) phthalate is an important metabolite of widely used phthalate plasticizers. |
|
V72258 | (rac)-N,O-Didesmethyl Tramadol-d3 | 1261398-22-4 | (rac)-N,O-Didesmethyl Tramadol-d3 is deuterium labeled (rac)-N,O-Didesmethyl Tramadol. |
|
V72221 | (S)-(+)-O-Desmethyl Venlafaxine ((S)-(+)-O-Desmethyl Venlafaxine) | 142761-12-4 | (S)-(+)-O-Desmethyl Venlafaxine is the S-enantiomer of O-Desmethyl Venlafaxine. |
|
V72230 | (S)-(+)-O-Desmethyl Venlafaxine-d6 ((S)-O-Desmethyl Venlafaxine d6) | 1062609-99-7 | (S)-(+)-O-Desmethyl Venlafaxine-d6 is the deuterated form of (S)-(+)-O-Desmethyl Venlafaxine. |
|
V72208 | (S)-Dehydro Venlafaxine | 2742899-98-3 | (S)-Dehydro Venlafaxine is the inactive S-enantiomer of Dehydro Venlafaxine. |
|
V72266 | (S)-O-Desmethyl Venlafaxine N-Oxide (SO-Desmethyl Venlafaxine N-Oxide) | 1021934-03-1 | (S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide of (S)-O-Desmethyl Venlafaxine. |
|
V77348 | (Z)-10-Hydroxynortriptyline-d3 | (Z)-10-Hydroxynortriptyline-d3 is the deuterated form of (Z)-10-Hydroxynortriptyline. | |
|
V77347 | (Z)2S,4R-Sacubitril (Sacubitril-Valsartan Impurity 12) | (Z)2S,4R-Sacubitril is an impurity of Sacubitri. | |
|
V72253 | (±)-11-Nor-9-carboxy-Δ9-THC | 104874-50-2 | (±)-11-Nor-9-carboxy-Δ9-THC is a metabolite of cannabis. |
|
V72141 | (±)-2-Propyl-4-pentenoic acid (4-en-VPA; 2-Allylpentanoic acid) | 1575-72-0 | (±)-2-Propyl-4-pentenoic acid (4-en-VPA) is the main toxic metabolite of Valproic acid. |
|
V72294 | 1'-Hydroxymidazolam-13C3 (Midazolam impurity 1-13C3) | 1189677-14-2 | 1'-Hydroxymidazolam-13C3 is a 13C (carbon 13)-labeled 1'-Hydroxymidazolam. |
|
V72249 | 1'-Hydroxymidazolam-d4 (Midazolam impurity 1-d4) | 1781843-10-4 | 1'-Hydroxymidazolam-d4 is a deuterated marker of 1'-Hydroxymidazolam. |
|
V72133 | 1,1,3-Tribromoacetone | 3475-39-6 | 1,1,3-Tribromoacetone is an impurity in methotrexate. |
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