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Drug Metabolite

Drug Metabolite

Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite. 

Drug Metabolite related products

Structure Cat No. Product Name CAS No. Product Description
(-)-Verrucarol V103485 (-)-Verrucarol 2198-92-7 (-)-verrucarol is a trichothecene sesquiterpenoid, which is a hydrolysis product of natural Verrucarin A.
(2'S)-Nicotine 1-oxide V107256 (2'S)-Nicotine 1-oxide 2820-55-5 (2'S)-Nicotine 1-oxide ((2S)-Nicotine 1-N-oxide) is an alkaloid N-oxide found in the leaves, stems and roots of tobacco (Nicotiana tabacum).
(2-Amino-5-bromophenyl)(pyridin-2-yl)methanone V106502 (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone 1563-56-0 (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone is a precursor for the synthesis of benzodiazepines and a hydrolysis product of clonazepam.
(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA) V72225 (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA) 13382-47-3 (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the major urinary metabolite of 1,4-Dioxane.
(25R)-12α-Hydroxyspirost-4-en-3-one V72236 (25R)-12α-Hydroxyspirost-4-en-3-one 50888-50-1 (25R)-12α-Hydroxyspirost-4-en-3-one is a minor metabolite generated by Nocardia globerula on Hecogenin.
(2S,4S)-沙库比曲 V32701 (2S,4S)-Sacubitril 149709-63-7 2S,4S-Sacubitril is an impurity of Sacubitril (AHU 377; AHU377;AHU-377), which is a US FDA approved drug used in combination with valsartan (trade name Entrosto for the combo)for the treatment of heart failure.
(3,4,5-Trimethoxyphenyl)acetic-2,2 Acid-d2 V72169 (3,4,5-Trimethoxyphenyl)acetic-2,2 Acid-d2 344299-45-2 (3,4,5-Trimethoxyphenyl)acetic-2,2 Acid-d2 is the deuterium labelled form of 3,4,5-Trimethoxyphenylacetic acid.
(3R)-Hydroxyquinidine V102935 (3R)-Hydroxyquinidine 60761-51-5 (3R)-Hydroxyquinidine is the major metabolite of quinidine.
(3R,5R)-Octahydrocurcumin V105906 (3R,5R)-Octahydrocurcumin 408324-14-1 (3R,5R)-Octahydrocurcumin (Compound 7) is a metabolite of curcumin by intestinal flora.
(3R,6S)-Bassiatin V119613 (3R,6S)-Bassiatin 172721-96-9 (3R,6S)-Brazilian (compound 5) is an enantiomer of the fungal metabolite brazilianin.
(3S,17S)-FD-895 V102621 (3S,17S)-FD-895 2598242-04-5 (3S,17S)-FD-895 is an analog of FD-895.
(3S,5S)-Octahydrocurcumin V105907 (3S,5S)-Octahydrocurcumin 112494-41-4 (3S,5S)-Octahydrocurcumin ((3S,5S)-hexahydrobisdemethoxycurcumin) is a fungal metabolite that can be isolated from turmeric.
(9Z)-16-Hydroxy-9-hexadecenoic acid V118562 (9Z)-16-Hydroxy-9-hexadecenoic acid 1619-68-7 (9Z)-16-hydroxy-9-hexadecenoic acid is an unsaturated hydroxy fatty acid.
(E)-10-Hydroxynortriptyline (E-10-OH-NT) V72147 (E)-10-Hydroxynortriptyline (E-10-OH-NT) 47132-16-1 (E)-10-Hydroxynortriptyline (E-10-OH-NT) is the metabolite of Nortriptyline.
(E/Z)-Etherolenic acid V104772 (E/Z)-Etherolenic acid 2247927-22-4 (E/Z)-Ethylene oleic acid is a divinyl ether oxidized lipid and a metabolite of linolenic acid.
(R)-(-)-O-Desmethyl Venlafaxine-d6 ((R)-O-Desmethyl Venlafaxine-d6) V72206 (R)-(-)-O-Desmethyl Venlafaxine-d6 ((R)-O-Desmethyl Venlafaxine-d6) 1062609-96-4 (R)-(-)-O-Desmethyl Venlafaxine-d6 is the deuterated form of (R)-(-)-O-Desmethyl Venlafaxine.
(R)-Amino-N-benzyl-3-methoxypropionamide V105889 (R)-Amino-N-benzyl-3-methoxypropionamide 196601-69-1 (R)-Amino-N-benzyl-3-methoxypropionamide is a stable intermediate of the antiepileptic drug lacosamide.
(R)-Desmethylcitalopram oxalate V116547 (R)-Desmethylcitalopram oxalate 852172-07-7 (R)-Demethylcitalopram oxalate is a metabolite of citalopram.
(R)-tert-OMe-byakangelicin V72217 (R)-tert-OMe-byakangelicin 89560-97-4 (R)-tert-OMe-byakangelicin is a furanocoumarin with inhibitory activity on hepatic drug metabolizing enzyme (DME) activity.
(R)-γ-Valerolactone V102628 (R)-γ-Valerolactone 58917-25-2 (R)-γ-Valerolactone is a precursor of antihypertensive compounds.
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