ATP-citrate lyase (ACLY) is a crucial metabolic enzyme that catalyzes the ATP-dependent conversion of citrate and coenzyme A (CoA) to oxaloacetate and acetyl-CoA. The biosynthesis of cholesterol, the metabolism of fatty acids, and the acetylation and prenylation of proteins all depend on the acetyl-CoA product. Additionally, acetylation reactions that alter proteins, like the acetylation of histones, require acetyl CoA.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V9382 | 2-Furoic acid | 88-14-2 | 2-Furoic acid is an orally bioactive heterocyclic carboxylic acid acting as a human cathepsin K inhibitor and is effective in lowering both serum cholesterol and serum triglyceride levels significantly in rats with an elevation of HDL cholesterol level at 20 mg/kg/day orally. |