ATP-citrate lyase

ATP-citrate lyase

ATP-citrate lyase (ACLY) is a crucial metabolic enzyme that catalyzes the ATP-dependent conversion of citrate and coenzyme A (CoA) to oxaloacetate and acetyl-CoA. The biosynthesis of cholesterol, the metabolism of fatty acids, and the acetylation and prenylation of proteins all depend on the acetyl-CoA product. Additionally, acetylation reactions that alter proteins, like the acetylation of histones, require acetyl CoA.

ATP-citrate lyase related products

Structure Cat No. Product Name CAS No. Product Description
V9382 2-Furoic acid 88-14-2 2-Furoic acid is an orally bioactive heterocyclic carboxylic acid acting as a human cathepsin K inhibitor and is effective in lowering both serum cholesterol and serum triglyceride levels significantly in rats with an elevation of HDL cholesterol level at 20 mg/kg/day orally.
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