GSNOR

GSNOR

S-Nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO).

Nitric oxide (NO) adduct S-nitrosoglutathione (GSNO), a crucial reservoir for NO bioactivity, is reduced by GSNOR. It has been discovered that GSNOR plays a key role in plant resistance to bacterial and fungal pathogens. The expression of GSNOR is widespread, and it catalyzes the denitrosylation of GSNO, which reduces protein S-nitrosylation in beta-cells.

GSNOR related products

Structure Cat No. Product Name CAS No. Product Description
V1914 N6022 1208315-24-5 N6022 is a selective, first-in-class and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with IC50 of 8 nM and Ki of 2.5 nM.
Contact Us