News

Cancer immunotherapy has expanded beyond T cells to include innate immune cells such as NK cells, which can kill tumor cells without prior antigen sensitization.

Realizing the therapeutic potential of antibodies requires simultaneously optimizing multiple properties, such as antigen-binding specificity, viscosity, clearance and immunogenicity

The Spt-Ada-Gcn5 acetyltransferase (SAGA) complex regulates gene expression through histone acetylation at promoters, mediated by its histone acetyl transferase (HAT), KAT2A.

Mechanical cues from the extracellular matrix (ECM) regulate various cellular processes.

Prostate cancer (PCa) represents a leading cause of cancer-related mortality in men.

Background: Resistance to immune checkpoint inhibitors (ICIs) in prostate cancer (PCa) is driven by a "cold" tumor immune microenvironment.

The widespread occurrence of antimicrobial-resistance-associated contaminants in natural and engineered water systems poses a major threat to environmental and public health.

Parkinson disease (PD) is closely linked to disruptions in mitochondrial quality control, a process regulated by the ubiquitin kinase PINK1 and the E3 ubiquitin ligase PRKN/parkin.

Circulating polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) and gut probiotics are crucial for alleviating experimental necrotizing enterocolitis (NEC) in mice, yet the mechanisms linking intestinal PMN-MDSCs (iPMN-MDSCs) to specific microbiota remain unclear.

Lymph nodes serve as strategic targets for cancer vaccines by enhancing interactions with antigen-presenting cells (APCs) and promoting immune activation.