A group of enzymes known as ATPases catalyze the breakdown of ATP into ADP and a free phosphate ion. Dephosphorylation releases energy, which the enzyme (typically) uses to fuel additional chemical reactions that would not otherwise take place. Some of these enzymes move solutes across the membrane against their concentration gradient because they are essential membrane proteins. Transmembrane ATPases are what these are. Many of the metabolites required for cell metabolism are imported by transmembrane ATPases, while toxins, waste products, and other solutes that may obstruct cellular processes are exported. For instance, the hydrogen potassium ATPase (also known as the gastric proton pump) and the sodium-potassium exchanger (also known as the Na+/K+ ATPase) are responsible for acidifying the stomach's contents.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V74156 | 3′-Acetate-ATP | 90290-58-7 | 3'-Acetate-ATP is an ATP analogue, a product of ATP acetylation, with maximum UV absorption at 259 nm (neutral pH water). |
|
V119398 | 6-Bn-ADP sodium | Sodium 6-Bn-ADP (N6-benzylADP) is a derivative of adenosine 5'-bisphosphate (ADP) that can inhibit ATP hydrolysis. | |
|
V112359 | Aloracetam | 119610-26-3 | Alloraceran is a cyclic derivative of γ-aminobutyric acid (GABA) that can cross the blood-brain barrier and has a good nootropic effect. |
|
V74155 | ATP synthase inhibitor 2 | 2814540-76-4 | ATP synthase inhibitor 2 is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL), which can completely inhibit the ATP synthesis activity of Pseudomonas aeruginosa (PA) at 128 μg/mL. |
|
V78152 | ATP Synthesis-IN-1 | ATP Synthesis-IN-1 (Compound 4) is a quinoline analogue and an effective inhibitor of PA ATP synthesis activity. | |
|
V108474 | Aurovertin B | 55350-03-3 | Aurovertin B is a natural product with anticancer activity. |
|
V130396 | BMS-199264 | 675833-20-2 | BMS-199264 is an F1F0 ATP hydrolase inhibitor (IC50=0.5 μM) with no inhibitory effect on F1F0 ATP synthase. |
|
V133002 | Cyclocreatine-13C3 | Cyclocreatine-13C3 is a 13C-labeled cyclic creatine. | |
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V138029 | IPH5201 | IPH5201 is a selective CD39 inhibitor and belongs to the humanized IgG1 monoclonal antibody family. | |
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V120112 | isoGDP trisodium | isoGDP (trisodium) is an isomer of GDP. | |
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V138439 | KI-DX-014 | 1309288-83-2 | KI-DX-014 is a DDX21 inhibitor with high RNA binding inhibitory activity (IC50 of 3.31 μM). |
|
V138703 | LC-MF-4 | LC-MF-4 is a selective FGFR3 PROTAC degrader with a DC50 of 30.89 nM in KMS-11 cells. | |
|
V112299 | Methyl pyruvate | 600-22-6 | Methyl pyruvate is a methyl ester derivative of pyruvate. |
|
V140926 | NAMPT activator-10 | 2237269-22-4 | NAMPT activator-10 is an orally effective NAMPT activator with a target Kd value of 0.64 μM. |
|
V141084 | ND-011458 | 1648720-01-7 | ND-011458 is an antibacterial agent, belonging to the QcrB inhibitor class, and is also an inhibitor of cytochrome bcc:aa3 oxidase function. |
|
V142010 | Ovothiol A disulfide | 73491-33-5 | Ovothiol A disulfide is an inhibitor of phototriggered CF1 ATPase activity. |
|
V142047 | P259 | P259 is a Drp1-Mff inhibitor. | |
|
V110778 | PRP020 | PRP020 is a potent and specific inhibitor of mycobacterial ATP synthase that does not inhibit succinate-driven acidification. | |
|
V85097 | Triciribine phosphate sodium (TCN-P sodium) | ||
|
V53259 | Venturicidin B (Aabomycin A2) | 33538-72-6 | Venturicidin B (Aabomycin A2) is a macrolide antibiotic extracted from Streptomyces and could be utilized as an antifungal agent and an effective inhibitor of the mitochondrial F0-ATP synthase (ATP synthase) complex. |
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