A group of enzymes known as ATPases catalyze the breakdown of ATP into ADP and a free phosphate ion. Dephosphorylation releases energy, which the enzyme (typically) uses to fuel additional chemical reactions that would not otherwise take place. Some of these enzymes move solutes across the membrane against their concentration gradient because they are essential membrane proteins. Transmembrane ATPases are what these are. Many of the metabolites required for cell metabolism are imported by transmembrane ATPases, while toxins, waste products, and other solutes that may obstruct cellular processes are exported. For instance, the hydrogen potassium ATPase (also known as the gastric proton pump) and the sodium-potassium exchanger (also known as the Na+/K+ ATPase) are responsible for acidifying the stomach's contents.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V74156 | 3′-Acetate-ATP | 90290-58-7 | 3'-Acetate-ATP is an ATP analogue, a product of ATP acetylation, with maximum UV absorption at 259 nm (neutral pH water). |
|
V74155 | ATP synthase inhibitor 2 | 2814540-76-4 | ATP synthase inhibitor 2 is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL), which can completely inhibit the ATP synthesis activity of Pseudomonas aeruginosa (PA) at 128 μg/mL. |
|
V78152 | ATP Synthesis-IN-1 | ATP Synthesis-IN-1 (Compound 4) is a quinoline analogue and an effective inhibitor of PA ATP synthesis activity. | |
|
V85097 | Triciribine phosphate sodium (TCN-P sodium) | ||
|
V53259 | Venturicidin B (Aabomycin A2) | 33538-72-6 | Venturicidin B (Aabomycin A2) is a macrolide antibiotic extracted from Streptomyces and could be utilized as an antifungal agent and an effective inhibitor of the mitochondrial F0-ATP synthase (ATP synthase) complex. |
|
V74154 | ZW290 | 2411852-67-8 | ZW290 is a compound that activates the thermogenic function of brown adipose tissue (BAT). |
|
V51633 | Oligomycins | 1404-19-9 | Oligomycin is an antifungal antibiotic and an inhibitor (blocker/antagonist) of H+-ATP synthase. |
|
V0064 | Oligomycin A (MCH-32) | 579-13-5 | Oligomycin A (also known as MCH 32)is a naturally occuring macrolide produced by Streptomyces. |
|
V51192 | Bongkrekic acid (BA) | 11076-19-0 | Bongkrekic Acid is a mitochondrial toxin produced by Pseudomonas sp. |
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