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Microtubule(Tubulin)

Microtubule(Tubulin)

Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.

Microtubule(Tubulin) related products

Structure Cat No. Product Name CAS No. Product Description
(E)-2-Hexadecenal V102777 (E)-2-Hexadecenal 22644-96-8 (E)-2-Hexadecenal (trans-2-hexadecenal), a MLK3 activator, induces cytoskeletal reorganization in human and mouse cells, leading to cell rounding, shedding, and ultimately apoptosis.
(R)-Colchicine V112184 (R)-Colchicine 75520-89-7 (R)-Colchicine is the R-isomer of colchicine.
(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran V105895 (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran 915095-94-2 (S)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)tetrahydrofuran (compound 2d) is a halogenated benadryl analog and a microtubule destabilizing agent.
(S)-Alyssin V94644 (S)-Alyssin 167963-04-4 (S)-Alyssin is an isomer of alyssin.
(S)-AM-9022 V103849 (S)-AM-9022 2446872-47-3 (S)-AM-9022 is the S-enantiomer of AM-9022.
10-去乙酰紫杉醇 V29322 10-Deacetyltaxol 78432-77-6 10-Deacetyltaxol (also called 10-Deacetylpaclitaxel), the 10-deacetylated form of paclitaxel, is a taxane analogue andimpurity of Paclitaxel extracted from Taxus wallichiana Zucc with anticancer activities.
17S-FD-895 V104791 17S-FD-895 2803326-64-7 17S-FD-895 is a tubulin aggregation inhibitor with anticancer activity.
2'-O-TBDMS-Paclitaxel V100448 2'-O-TBDMS-Paclitaxel 114655-02-6 2'-O-TBDMS-Paclitaxel is a paclitaxel derivative in which the 2'-OH group is substituted and protected with tert-butyldimethylsilane (TBDMS) ether.
3,4',5-Trismethoxybenzophenone V84553 3,4',5-Trismethoxybenzophenone 94709-12-3
3,4,3'-Tri-O-methylflavellagic acid V109630 3,4,3'-Tri-O-methylflavellagic acid 13756-49-5 3,4,3'-Tri-O-methylbaicaleic acid is a flavonoid inhibitor that targets αβ-tubulin (colchicine binding site) and polo-like kinase-1 (PLK-1), and can be isolated from the roots of *Anogeissus leiocarpus*.
3-Demethylthiocolchicine V96697 3-Demethylthiocolchicine 87424-25-7 3-Demethylthiocolchicine is a colchicine analog with broad-spectrum antitumor activity.
6-MOMIPP V116024 6-MOMIPP 1961272-45-6 6-MOMIPP is a microtubule disruptor that can cross the blood-brain barrier and target the colchicine binding site on β-tubulin.
7,10-o-ditroc 多西他赛，7,10-o-ditroc 多烯紫杉醇 V92647 7,10-o-ditroc docetaxel 114915-14-9 7,10-o-ditroc docetaxel is a taxol analog and a microtubule depolymerization inhibitor that works by binding to stabilized microtubules.
7-Acetyl paclitaxel V103184 7-Acetyl paclitaxel 92950-39-5 7-Acetylpaclitaxel is a microtubule depolymerization inhibitor that inhibits calcium-induced microtubule depolymerization.
7-Benzoyloxindole V112406 7-Benzoyloxindole 51135-38-7 7-Benzoylindole (compound 4a) is a microtubule destabilizer.
7-表紫杉醇 V34036 7-epi-Taxol 105454-04-4 7-epi-Taxol, the epimer of taxol (paclitaxel), is a major and active metabolite of taxol isolated fromTaxus brevifolia with comparable anticancr/antitubulin activityto that of paclitaxek/taxol.
A-259745 V117153 A-259745 256934-83-5 A-259745 is an orally effective antimitotic agent that binds to the colchicine binding site of tubulin.
ABJ-879 V115875 ABJ-879 252981-48-9 ABJ-879 is a derivative of epothilone.
ABT-751 hydrochloride V88427 ABT-751 hydrochloride 141450-48-8 ABT-751 (E7010) hydrochloride is a novel, highly orally bioavailable sulfonamide antimitotic compound and tubulin binding agent.
ADC Control Human IgG1-vcMMAE V88374 ADC Control Human IgG1-vcMMAE ADC Control Human IgG1-vcMMAE is a human monoclonal antibody, which is the isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization.
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