Microtubule(Tubulin)

Microtubule(Tubulin)

Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.

Microtubule(Tubulin) related products

Structure Cat No. Product Name CAS No. Product Description
V29322 10-Deacetyltaxol 78432-77-6 10-Deacetyltaxol (also called 10-Deacetylpaclitaxel), the 10-deacetylated form of paclitaxel, is a taxane analogue andimpurity of Paclitaxel extracted from Taxus wallichiana Zucc with anticancer activities.
V34036 7-epi-Taxol 105454-04-4 7-epi-Taxol, the epimer of taxol (paclitaxel), is a major and active metabolite of taxol isolated fromTaxus brevifolia with comparable anticancr/antitubulin activityto that of paclitaxek/taxol.
V35084 Amiprofos methyl (BAY-NTN 6867) 36001-88-4
V51606 Ansamitocin analog (20-O-Demethyl-AP3) 72902-38-6 Ansamitocin analog (20-O-Demethyl-AP3) is one of ansamitocin P-3's minor metabolites.
V29720 Ansamitocin P-3 (Antibiotic C 15003P3'; Maytansinol butyrate) 66584-72-3 Ansamitocin P-3 (Maytansinol isobutyrate; NSC-292222;Antibiotic C 15003P3) is a potent microtubule/antimitotic inhibitor used as an warhead of ADC (antibody drug conjugate).
V78086 Anti-α-Tubulin Antibody, AF555 conjugate
V77986 Anticancer agent 139
V34998 Anticancer agent 98 2857070-72-3
V34829 Antiproliferative agent-14 1885900-35-5
V78056 Antiproliferative agent-23
V55250 Antiproliferative agent-30 2713553-88-7
V79807 Antitubulin agent 1
V5180 Auristatin E 160800-57-7 Auristatin E,a synthetic analog of dolastatin 10, is a novel and highly cytotoxic tubulin inhibitor with antitumor activity; it is a MMAE analog and cytotoxin used in Antibody-drug conjugates.
V52340 Bis-ANS dipotassium 65664-81-5
V13004 BNC-105 945771-74-4 BNC105 is a potentbenzofuran-basedtubulin polymerization inhibitor and also avascular disrupting agent (VDA) prodrug with potential anti-vascular and anticancer activities.
V3229 BTB-1 86030-08-2 BTB-1 is a novel, potent and the first small molecule inhibitor of the mitotic motor protein Kif18A.
V52300 Cantuzumab mertansine (mocantuzumab; SB-408075; huC242-DM1) 400010-39-1
V52299 Cantuzumab ravtansine (IMGN242; huC242-DM4) 868747-45-9
V17952 Cevipabulin 849550-05-6 Cevipabulin (formerly D-06576;TTI-237) is a triazolopyrimidine based microtubule targeting agent/tubulin inhibitor with potential antitumor activity.
V55261 cis-Trismethoxy resveratrol ((Z)-3,5,4'-Trimethoxystilbene) 94608-23-8
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