Microtubule(Tubulin)

Microtubule(Tubulin)

Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.

Microtubule(Tubulin) related products

Structure Cat No. Product Name CAS No. Product Description
V29322 10-Deacetyltaxol 78432-77-6 10-Deacetyltaxol (also called 10-Deacetylpaclitaxel), the 10-deacetylated form of paclitaxel, is a taxane analogue andimpurity of Paclitaxel extracted from Taxus wallichiana Zucc with anticancer activities.
V84553 3,4',5-Trismethoxybenzophenone 94709-12-3
V34036 7-epi-Taxol 105454-04-4 7-epi-Taxol, the epimer of taxol (paclitaxel), is a major and active metabolite of taxol isolated fromTaxus brevifolia with comparable anticancr/antitubulin activityto that of paclitaxek/taxol.
V84913 AM-9022 2446872-46-2
V35084 Amiprofos methyl (BAY-NTN 6867) 36001-88-4 Amiprofos methyl (BAY-NTN 6867) is a phosphate amide herbicide.
V51606 Ansamitocin analog (20-O-Demethyl-AP3) 72902-38-6 Ansamitocin analog (20-O-Demethyl-AP3) is one of ansamitocin P-3's minor metabolites.
V29720 Ansamitocin P-3 (Antibiotic C 15003P3'; Maytansinol butyrate) 66584-72-3 Ansamitocin P-3 (Maytansinol isobutyrate; NSC-292222;Antibiotic C 15003P3) is a potent microtubule/antimitotic inhibitor used as an warhead of ADC (antibody drug conjugate).
V78086 Anti-α-Tubulin Antibody, AF555 conjugate Anti-α-Tubulin Antibody, AF555 conjugate is a conjugate of mouse anti-α-tubulin monoclonal antibody (mAb) and the red fluorescent dye Alexa Fluor 555, which may be utilized to detect tubulin (Ex/Em: 554/567 nm).
V77986 Anticancer agent 139 Anticancer agent 139 (Compound 6h) has potent anti-cancer activity.
V34998 Anticancer agent 98 2857070-72-3 Anticancer agent 98 (compound 12k) is a tubulin polymerization inhibitor (Kd=16.9 μM).
V34829 Antiproliferative agent-14 1885900-35-5 antiproliferation agent-14 (compound 3b) is a potent inhibitor of tubulin polymerization with IC50 of 3.41 μM.
V78056 Antiproliferative agent-23 antiproliferation agent-23 is a microtubule destabilizing agent (MDA) that effectively interferes with the tubulin-microtubule system.
V55250 Antiproliferative agent-30 2713553-88-7 antiproliferation agent-30 (Compound 8g) inhibits tubulin assembly and inhibits FLT3 and Abl1.
V79807 Antitubulin agent 1 Antitubulin agents-1 is an antitubulin agent that induces disruption of microtubules (Microtubule/Tubulin) and increases α-tubulin acetylation.
V83574 Antitumor agent-138 2975168-22-8
V5180 Auristatin E 160800-57-7 Auristatin E,a synthetic analog of dolastatin 10, is a novel and highly cytotoxic tubulin inhibitor with antitumor activity; it is a MMAE analog and cytotoxin used in Antibody-drug conjugates.
V52340 Bis-ANS dipotassium 65664-81-5 Bis-ANS dipotassium is a protein fluorescent probe.
V13004 BNC-105 945771-74-4 BNC105 is a potentbenzofuran-basedtubulin polymerization inhibitor and also avascular disrupting agent (VDA) prodrug with potential anti-vascular and anticancer activities.
V3229 BTB-1 86030-08-2 BTB-1 is a novel, potent and the first small molecule inhibitor of the mitotic motor protein Kif18A.
V52300 Cantuzumab mertansine (mocantuzumab; SB-408075; huC242-DM1) 400010-39-1 Cantuzumab mertansine (SB-408075; huC242-DM1) is an ADC that is an immunoconjugate of a potent maytansine analogue and a humanized monoclonal antibody (mAb) against CanAg (huC242).
Contact Us Back to top