|
V83537
|
(R)-MrgprX2 antagonist-3
|
2642174-20-5 |
|
|
V4494
|
(S)-ZINC-3573
|
2095596-11-3 |
(S)-ZINC-3573 is the inactive enantiomer of ZINC-3573. |
|
V78342
|
BAM(8-22) TFA
|
|
BAM(8-22) TFA, a proteolytic cleavage product of proenkephalin A, is a potent activator of Mas-related G protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces in mice a Mrgpr-dependent manner. |
|
V2517
|
MRGPRX1 agonist 1
|
2377379-39-8 |
MRGPRX1 agonist 1 is a novel and highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1) (EC50 = 50 nM) with analgesic effects. |
|
V75464
|
MrgprX2 antagonist-1
|
2642162-06-7 |
MrgprX2 antagonist-1 is an antagonist of MrgprX2. |
|
V75469
|
MrgprX2 antagonist-2
|
2642346-30-1 |
MrgprX2 antagonist-2 is an antagonist of MrgprX2. |
|
V75470
|
MrgprX2 antagonist-3
|
2642174-19-2 |
MrgprX2 antagonist-3 is an antagonist of MrgprX2. |
|
V75468
|
MrgprX2 antagonist-4
|
2641398-04-9 |
MrgprX2 antagonist-4 is an antagonist of MrgprX2. |
|
V75465
|
MrgprX2 antagonist-5
|
2527815-74-1 |
MrgprX2 antagonist-5 is an antagonist of MrgprX2. |
|
V86662
|
MRGPRX2 modulator-1
|
|
MRGPRX2 modulator-1 (example 17) is a mas-related g protein receptor x2 (MRGPRX2) modulator. |
|
V75467
|
Mrgx2 antagonist-2
|
2767111-67-9 |
Mrgx2 antagonist-2 is a Mrgx2 antagonist (refer to Example 123 in the patent) with pIC50 of 8.6. |
|
V81036
|
PAMP-12 (unmodified) (TFA)
|
|
PAMP-12 (unmodified) TFA is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM). |
|
V75466
|
ZINC49534341
|
1274013-03-4 |
ZINC49534341 is an MRGPRX2 antagonist (inhibitor) with Ki of 32 nM. |