The ADIPOQ gene in humans produces the protein adiponectin. Both the breakdown of fatty acids and glucose levels are regulated by it. The hormone helps to suppress the metabolic disturbances that can lead to type 2 diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease, and act as a standalone risk factor for metabolic syndrome. Numerous receptors bind to adiponectin. Adiponectin receptors 1 and 2 have been identified as two receptors with homology to G protein-coupled receptors and one receptor similar to the cadherin family.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V1956 | AdipoRon (SC-396658) | 924416-43-3 | AdipoRon (also known as SC-396658) is a novel, first-in-class, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively. |
|
V5100 | Arctiin (Arctii; NSC 315527; Arctigenin-4-glucoside) | 20362-31-6 | Arctiin (formerly known as NSC 315527), a plant lignan that is isolated from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. |
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