Na+Ca2+ Exchanger

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Na+Ca2+ Exchanger

Calcium is removed from cells by the antiporter membrane protein called Na+/Ca2+ exchanger (also known as sodium-calcium exchanger, or NCX). In exchange for the countertransport of calcium ions (Ca2+), it allows sodium (Na+) to flow across the plasma membrane along its electrochemical gradient, utilizing the energy that is stored there. A single calcium ion is removed by a Na+/Ca2+ exchanger in exchange for the import of three sodium ions.Animal species and a wide variety of cell types contain Na+/Ca2+ exchangers. One of the most significant cellular mechanisms for removing Ca2+ is the Na+/Ca2+ exchanger. The Na+/Ca2+ exchanger has a low affinity for Ca2+ but a high capacity, allowing it to move up to 5,000 Ca2+ ions per second while still transporting the ions quickly. After an excitotoxic insult, the Na+/Ca2+ exchanger probably has a significant impact on how quickly the cell's calcium concentrations return to normal.

Na+Ca2+ Exchanger related products

Cat No.	Product Name	CAS No.	Product Description
V100305	2-Oxo-zoniporide hydrochloride	372078-42-7	2-Oxo-zoniporide hydrochloride is an orally active sodium hydrogen exchanger type 1 (NHE-1) inhibitor that can be used to study myocardial ischemic injury.
V101023	KB-R7943	182004-64-4	KB-R7943 (Compound 1) is an inhibitor of the sodium-calcium exchanger with an IC50 of 5.1 μM.
V2918	SEA0400	223104-29-8	SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor.
V87179	UTX-143		UTX-143 is a Na+/H+ exchanger protein (NHE5) inhibitor.
V74206	YM-244769 dihydrochloride	1780390-65-9	YM-244769 di-HCl is a specific, orally bioactive Na+/Ca2+ exchanger (NCX) inhibitor.
V98862	Zoniporide	241800-98-6	Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity.
V32490	Benzamil hydrochloride	161804-20-2	Benzamil HCl, the hydrochloride salt of Benzamil which isan amiloride analog, is aNa+/Ca2+ exchanger (NCX) inhibitor(IC50~100 nM) with the potential totreat cystic fibrosis.