ACE

ACE

By making blood vessels tighten, the angiotensin-converting enzyme (ACE) indirectly raises blood pressure. Angiotensin I is changed by ACE into angiotensin II, which tightens the blood vessels. The renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body, is made up of ACE, angiotensin I, and angiotensin II. Cells in the endothelium (inner layer) of blood vessels secrete ACE in the lungs and kidneys. It serves two main purposes: In a substrate concentration-dependent manner, ACE catalyzes the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor.Bradykinin, a potent vasodilator, and other vasoactive peptides are broken down by ACE. In order to treat conditions like high blood pressure, heart failure, diabetic nephropathy, and type 2 diabetes mellitus, ACE inhibition is a goal. Angiotensin II production and bradykinin metabolism are both reduced when ACE is inhibited (by ACE inhibitors), which results in a general dilation of the arteries and veins and a reduction in arterial blood pressure.

ACE related products

Structure Cat No. Product Name CAS No. Product Description
V72996 (R)-MLN-4760 305335-29-9
V73020 [Tyr6]-Angiotensin II 52634-95-4
V73001 Abz-Ser-Pro-3-nitro-Tyr 553644-01-2
V2463 Acetyl tetrapeptide-5 820959-17-9 Acetyl Tetrapeptide-5(also known asEyeseryl),Inhibits skin glycosylation, reduces skin edema, removes dark circles and reduce bags under the eyes
V72998 Bradykinin potentiator B (Bradykinin potentiating peptide B) 30892-86-5
V73012 Camellianin B (Camellia flavonoid glycoside B) 109232-76-0
V73006 Delapril-d3 hydrochloride (delapril hydrochloride d3 (hydrochloride)) 2714473-25-1
V72992 DX600 478188-26-0
V72997 Enalaprilat-d5 (Enalaprilat D5; MK-422 d5) 349554-00-3
V73005 FA-Phe-Phe 83661-95-4
V73016 Ganoderic acid K 104700-95-0
V72993 H-Ile-Pro-Pro-OH hydrochloride 1208862-61-6
V73011 H-Lys-Trp-OH 50674-18-5
V73017 H-Pro-Phe-OH 13589-02-1
V73009 H-Trp-Phe-OH 6686-02-8
V73015 H-Tyr-Lys-OH 54925-88-1
V73004 Imidapril-d3 hydrochloride (Imidapril d3 hydrochloride) 1356017-30-5
V73014 Isocrenatoside 221895-09-6
V73013 Isomartynoside 94410-22-7
V72990 L-Isoleucyl-L-arginine 55715-01-0
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