CMV

CMV

The common herpesvirus family includes the double-stranded DNA virus known as cytomegalovirus (CMV). Cytomegaloviruses evade immune clearance and endure for the entirety of the infected host's life. However, the balance of this virus-host interaction is unstable and depends on the cellular immune response, which typically necessitates the activity of particular CD8 T lymphocytes.

The herpesvirus family, also known as the herpesviridae or human herpesvirus-5 (HHV-5), includes the human cytomegalovirus. Salivary glands and human cytomegalovirus infections are frequently linked. While CMV infection may not cause any symptoms in healthy individuals, it can be fatal in an immunocompromised patient. Congenital cytomegalovirus infection can be fatal or cause serious illness. CMV frequently remains dormant after infection, but it could reactivate at any time. It eventually results in mucoepidermoid carcinoma and is thought to be the cause of prostate cancer.

CMV related products

Structure Cat No. Product Name CAS No. Product Description
V35042 Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 207226-35-5
V52093 Fiztasovimab (NPC-21; EV2038) 2467411-25-0
V54158 Fomivirsen (ISIS-2922 free base) 144245-52-3
V3910 LETERMOVIR 917389-32-3 Letermovir (formerly MK-8828;MK8828; AIC-246; AIC246;trade name:Prevymis) is a potent anti-cytomegalovirus (CMV) / antiviral drug approved on 11/8/2017 by FDA to prevent infection after bone marrow transplant.
V4957 Maribavir 176161-24-3 Maribavir (1263W94;BW-1263W94;GW-1263; SHP-620;GW-257406X; VP-41263; Livtencity),an experimental oral antiviral (anti-CMV) drug candidate, is a novel and potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro with an IC50of 3 nM.
V54159 Regavirumab (MCA C23; TI-23) 153101-26-9
V54160 SB-734117 607368-97-8
V36809 Sevirumab (MSL-109) 138660-96-5
V4218 Tomeglovir 233254-24-5 Tomeglovir (also known as BAY-38-4766) is a novel, potent andnon-nucleoside anti-CMV (cytomegalovirus) agent which inhibits processing of viral DNA-concatemers withIC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
V81615 Tricin-d6
V52560 Valganciclovir-d5 TFA (Valganciclovir-d5) 1402924-31-5
V52550 Valganciclovir-d8 hydrochloride (Valganciclovir-d8 hydrochloride) 1132088-63-1
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