Mitophagy is the selective degradation of mitochondria by autophagy.

The vital organelles known as mitochondria control the homeostasis of cellular energy and cell death. Therefore, it is essential for preserving healthy cellular processes that damaged mitochondria are eliminated through autophagy, also known as mitophagy. In fact, it has recently been suggested that mitophagy is essential for neurodegenerative diseases, ischemia- or drug-induced tissue injury, paternal mitochondrial degradation, red blood cell terminal differentiation, and other processes.

Mitophagy and autophagy are crucial cellular processes that break down the contents of cells, conserve energy, and prevent the buildup of broken and aggregated biomolecules.

Mitophagy related products

Structure Cat No. Product Name CAS No. Product Description
V25573 Mitochonic Acid 5 1354707-41-7 Mitochonic acid 5 binds to mitochondria and improves renal tubular and cardiomyocyte damage.
V75785 MTX115325 2750895-97-5 MTX115325 (Example 1) is an orally bioavailable, brain-penetrating USP30 inhibitor (IC50=12 nM) with neuro-protection activity.
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