|
V1800
|
Exemestane (FCE 24304; EXE)
|
107868-30-4 |
Exemestane (formerly also known as FCE24304, PNU155971; FCE 24304; EXE), a drug usedin ER-positive breast cancer,is a synthetic and potent aromatase inhibitor, which inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively. |
|
V1798
|
Letrozole (CGS 20267)
|
112809-51-5 |
Letrozole (formerly known as CGS-20267; trade name: Femara; Letoval) is a third generation, nonsteroidal inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays and has anticancer activities. |
|
V1802
|
Aminoglutethimide (BA-16038)
|
125-84-8 |
Aminoglutethimide (also known as BA-16038, NSC-330915)is anananticancer drug that acts as a nonsteroidal aromatase inhibitor with IC50 of 10 μM. |
|
V20899
|
Fadrozole (CGS 16949A)
|
102676-47-1 |
Fadrozole(CGS 16949A) is a highly potent and selective nonsteroidal aromatase inhibitor (IC50 of 6.4 nM) with potential antineoplastic activity. |
|
V1801
|
Formestane (CGP-32349)
|
566-48-3 |
Formestane (formerly also known as CGP-32349, NSC 282175)is a second generation, selective, orally bioactive and synthetic steroidal aromatase inhibitor with an IC50 of 80 nM. |
|
V1799
|
Anastrozole (ZD1033)
|
120511-73-1 |
Anastrozole (formerly known as ZD-1033)is a potent, third-generation nonsteroidal and selective inhibitor of aromatase with anIC50of 15 nM for inhibiting human placental aromatase. |