Adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine and epinephrine.These receptors are found on numerous cells, and when a catecholamine binds to one of these receptors, the sympathetic nervous system is typically stimulated. The fight-or-flight response, which entails dilating the pupils of the eyes, mobilizing energy, and rerouting blood flow away from skeletal muscle to non-essential organs, is controlled by the sympathetic nervous system.There are numerous subtypes of the two main groups of adrenergic receptors, and. The receptor subtypes 1 and 2 exist. There are three subtypes of receptors: 1, 2, and 3. They are all associated with Gs proteins, which are associated with adenylate cyclase. Thus, antagonist binding increases the level of the second messenger cAMP inside of the cell. The cAMP-dependent protein kinase (PKA), one of cAMP's downstream effectors, mediates some intracellular processes after hormone binding.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V71347 | (+)-Sotalol ((S)-Sotalol) | 30236-32-9 | (+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol. |
|
V101112 | (-)-Isoproterenol hydrochloride | 5984-95-2 | (-)-Isoproterenol (L-isoproterenol; Proternol L) hydrochloride is a β-adrenergic receptor agonist. |
|
V71260 | (-)-Scopolamine (Atroscine) | 138-12-5 | (-)-Scopolamine (Atroscine) is an isomer of Scopolamine. |
|
V116575 | (1R,2S)-Dihydrobupropion | 292055-72-2 | (1R,2S)-dihydrobupropion is a norepinephrine-dopamine reuptake inhibitor and one of the active metabolites of bupropion. |
|
V112149 | (2S,3S)-Zenidolol hydrochloride | 1236034-74-4 | (2S,3S)-Zenidolol ((2S,3S)-ICI-118551) hydrochloride is a β2-adrenergic receptor (β2AR) antagonist with a pKi value of 7.51 for β1AR and 9.27 for β2AR. |
|
V71318 | (Des-His6)-ACTH (1-24) (human, bovine, rat) | 1926163-11-2 | (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analog of adrenocorticotropic hormone (ACTH). |
|
V121757 | (E)-8-Dodecenyl acetate | 38363-29-0 | (E)-8-Dodecenyl acetate is a sex pheromone that targets olfactory receptors in male golden moths and acts as an agonist. |
|
V71238 | (R)-(+)-Atenolol | 56715-13-0 | (R)-(+)-Atenolol is the less active enantiomer of (R,S)-atenolol. |
|
V79234 | (R)-9-Hydroxy Risperidone-d4 | (R)-9-Hydroxy Risperidone-d4 is the deuterium labelled form of (R)-9-Hydroxy Risperidone. | |
|
V121921 | (R)-Doxazosin | 70918-17-1 | (R)-Doxazosin is an isomer of doxazosin, a selective orally active α1-adrenergic receptor agonist. |
|
V71303 | (R)-Metoprolol-d7 (Metoprolol d7) | 1292907-84-6 | (R)-Metoprolol-d7 is the deuterium labelled form of Metoprolol. |
|
V40138 | (R)-Carvedilol | 95093-99-5 | (R)-Carvedilol is an optically active and R-enantiomer of Carvedilol, which is a nonselective ß-adrenergic blocker with a1-blocking activity. |
|
V70516 | (R,R)-Reboxetine mesylate ((R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate) | 105017-39-8 | (R,R)-Reboxetine mesylate is an antidepressant with good bioavailability. |
|
V71297 | (rac)-Dobutamine-d4 hydrochloride | 1246815-74-6 | (rac)-Dobutamine-d4 ( HCl) is the deuterated racemate of Dobutamine HCl. |
|
V71323 | (rac)-Dobutamine-d6 hydrochloride | 1246818-96-1 | (rac)-Dobutamine-d6 ( HCl) is the deuterated racemate of Dobutamine HCl. |
|
V87631 | (Rac)-Nebivolol-d2,15N | (Rac)-Nebivolol-d2,15N is 15N and deuterium labeled (Rac)-Nebivolol. | |
|
V71355 | (rac)-Nebivolol-d4 (Nebivolol-d4) | 1219407-55-2 | (rac)-Nebivolol-d4 is the deuterated racemate of Nebivolol. |
|
V84080 | (Rac)-Nebivolol-d4 hydrochloride ((Rac)-R 065824-d4 hydrochloride) | 2701283-32-9 | |
|
V122030 | (Rac)-Norepinephrine-d3 formate | (Rac)-Norepinephrine-d3 formate is a deuterium-labeled norepinephrine. | |
|
V122040 | (Rac)-Silodosin | 160970-64-9 | (Rac)-Silodosin is the racemic form of silodosin. |
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